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Submissions from 2015

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Cortical alpha activity predicts the confidence in an impending action, Jan Kubanek, N. Jeremy Hill, Lawrence H. Snyder, and Gerwin Schalk

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Cognitive and action-based aspects of developing decisions in parietal cortex, Jan Kubanek and Eric Mooshagian

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Reward-based decision signals in parietal cortex are partially embodied, Jan Kubanek and Lawrence H. Snyder

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Agitation down-regulates immunoglobulin binding protein EibG expression in Shiga toxin-producing Escherichia coli (STEC), Thorsten Kuczius, Wenlan Zhang, Viktor Merkel, Alexander Mellmann, Phillip I. Tarr, and Helge Karch

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Human DNA ligase III bridges two DNA ends to promote specific intermolecular DNA end joining, Vandna Kukshal, In-Kwon Kim, Gregory L. Hura, Alan E. Tomkinson, John A. Tainer, and Tom Ellenberger

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Trade-offs in the effects of the apolipoprotein E polymorphism on risks of diseases of the heart, cancer, and neurodegenerative disorders: Insights on mechanisms from the long life family study, Alexander M. Kulminski, Konstantin G. Arbeev, Irina Culminskaya, Svetlana V. Ukraintseva, Eric Stallard, Michael A. Province, and Anatoli I. Yashin

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Correlation between psychological stress levels and the severity of overactive bladder symptoms, Henry Lai, Vivien Gardner, Joel Vetter, and Gerald L. Andriole

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Nonmodifiable factors and complications contribute to length of stay in robot-assisted partial nephrectomy, Jeffrey A. Larson, Jihad H. Kaouk, Michael D. Stifelman, Craig G. Rogers, Mohamad E. Allaf, Aaron Potretzke, Susan Marshall, Homayoun Zargar, Mark W. Ball, and Sam B. Bhayani

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The Relevance of the Colon to Zinc Nutrition, Geetha Lavaniya Gopalsamy, David H. Alpers, Henry J. Binder, Cuong D. Tran, B. S. Ramakrishna, Ian Brown, Mark Manary, Elissa Mortimer, and Graeme P. Young

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IgG4-associated orbital and ocular inflammation, Cecilia S. Lee, George J. Harocopos, Courtney L. Kraus, Aaron Y. Lee, Gregory P. Van Stavern, Steven M. Couch, and P. Kumar Rao

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IgG4-associated orbital and ocular inflammation, Cecilia S. Lee, George J. Harocopos, Courtney L. Kraus, Aaron Y. Lee, Gregory P. Van Stavern, Steven M. Couch, and P. Kumar Rao

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Pulmonary Function Following Adult Spinal Deformity Surgery: Minimum Two-Year Follow-up, Ronald A. Lehman Jr., Daniel G. Kang, Lawrence G. Lenke, Jeremy J. Stallbaumer, and Brenda A. Sides

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Long-term safety and efficacy of antithymocyte globulin induction: Use of integrated national registry data to achieve ten-year follow-up of 10-10 Study participants, Krista L. Lentine, Mark A. Schnitzler, Huiling Xiao, and Daniel C. Brennan

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Effects of CD2-associated protein deficiency on amyloid-β in neuroblastoma cells and in an APP transgenic mouse model, Fan Liao, Hong Jiang, Subhashini Srivatsan, Qingli Xiao, Katheryn B. Lefton, Kaoru Yamada, Thomas E. Mahan, Jin-Moo Lee, Andrey S. Shaw, and David M. Holtzman

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Expression of five acetylcholine receptor subunit genes in Brugia malayi adult worms, Ben-Wen Li, Amy C. Rush, and Gary J. Weil

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Genetic heterogeneity of induced pluripotent stem cells: Results from 24 clones derived from a single C57BL/6 mouse, Cheng Li, Jeffrey M. Klco, Nichole M. Helton, Daniel R. George, Jacqueline L. Mudd, Christopher A. Miller, Charles Lu, Robert Fulton, Michelle O'Laughlin, Catrina Fronick, Richard K. Wilson, and Timothy J. Ley

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Role of hypoxia inducible factor-1α (HIF-1α) in innate defense against uropathogenic Escherichia coli infection, Ann E. Lin, Federico C. Beasley, Joshua Olson, Nadia Keller, Robert A. Shalwitz, Thomas J. Hannan, Scott J. Hultgren, and Victor Nizet

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Novel APC promoter and exon 1B deletion and allelic silencing in three mutation-negative classic familial adenomatous polyposis families, Yiing Lin, Shin Lin, Melanie D. Baxter, Lawrence Lin, Susan M. Kennedy, Zhengyan Zhang, Paul J. Goodfellow, William C. Chapman, and Nicholas O. Davidson

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Complement regulator CD46: Genetic variants and disease associations, M. Kathryn Liszewski and John P. Atkinson

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Influence of model boundary conditions on blood flow patterns in a patient specific stenotic right coronary artery, Biyue Liu, Jie Zheng, Richard Bach, and Dalin Tang

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Vasohibin-1 suppresses colon cancer, Shuai Liu, Bing Han, Qunyuan Zhang, Jie Dou, Fang Wang, Wenli Lin, Yuping Sun, and Guangyong Peng

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A first-in-human study of AMG 208, an oral MET inhibitor, in adult patients with advanced solid tumors, A. Craig Lockhart and et al

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A cost-effective junior resident training and assessment simulator for orthopaedic surgical skills via Fundamentals of Orthopaedic Surgery, Gregory Lopez, Rick Wright, David Martin, James Jung, Daniel Bracey, and Ranjan Gupta

A Cost-Effective Junior Resident Training and Assessment Simulator for Orthopaedic Surgical Skills via Fundamentals of Orthopaedic Surgery, Gregory Lopez, Rick Wright, David Martin, James Jung, Daniel Bracey, and Ranjan Gupta

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Model-driven mapping of transcriptional networks reveals the circuitry and dynamics of virulence regulation, Ezekiel J. Maier, Brian C. Haynes, Stacey R. Gish, Zhuo A. Wang, Michael L. Skowyra, Alyssa L. Marulli, Tamara L. Doering, and Michael R. Brent

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Adipose-derived mesenchymal stromal cells modulate tendon fibroblast responses to macrophage-induced inflammation in vitro, Cionne N. Manning, Catherine Martel, Shelly E. Sakiyama-Elbert, Matthew J. Silva, Shivam Shah, Richard H. Gelberman, and Stavros Thomopoulous

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A CDC20-APC/SOX2 signaling axis regulates human glioblastoma stem-like cells, Diane D. Mao, Amit D. Gujar, Tatenda Mahlokozera, Ishita Chen, Yanchun Pan, Jingqin Luo, Tayler Brost, Elizabeth A. Thompson, Alice Turski, Eric C. Leuthardt, Gavin P. Dunn, Michael R. Chicoine, Keith M. Rich, Joshua L. Dowling, Gregory J. Zipfel, Ralph G. Dacey, Samuel Achilefu, David D. Tran, Hiroko Yano, and Albert H. Kim

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Inherited coding variants at the CDKN2A locus influence susceptibility to acute lymphoblastic leukaemia in children, Elaine Mardis, Robert Fulton, and et al.

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Metastatic melanoma – A review of current and future treatment options, Emanual Maverakis, Lynn A. Cornelius, Glen M. Bowen, Tiffany Phan, Falin B. Patel, Sarah Fitzmaurice, Young He, Barbara Burrall, Christopher Duong, April M. Kloxin, Hawa Sultani, Reason Wilken, Steve R. Martinez, and Forum Patel

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Brown-pigmented Mycobacterium mageritense as a cause of prosthetic valve endocarditis and bloodstream infection, Allison R. McMullen, Caline Mattar, Nigar Kirmani, and Carey-Ann D. Burnham

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Association of lower fractional flow reserve values with higher risk of adverse cardiac events for lesions deferred revascularization among patients with acute coronary syndrome, Shriti Masrani Mehta, Jeremiah P. Depta, Eric Novak, Jayendrakumar S. Patel, Yogesh Patel, David Raymer, Gabrielle Facey, Alan Zajarias, John M. Lasala, Jasvindar Singh, Richard G. Bach, and Howard I. Kurz

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Global analyses revealed age-related alterations in innate immune responses after stimulation of pathogen recognition receptors, Talibah U. Metcalf, Rafael A. Cubas, Khader Ghneim, Michael J. Cartwright, Julien Van Grevenynghe, Justin M. Richner, David P. Olagnier, Peter A. Wilkinson, Mark J. Cameron, Byung S. Park, John B. Hiscott, Michael S. Diamond, Anne M. Wertheimer, Janko Nikolich-Zugich, and Elias K. Haddad

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Prevalence of classic, MLB-clade and VA-clade Astroviruses in Kenya and The Gambia, Caroline T. Meyer, Irma K. Bauer, Martin Antonio, Mitchell Adeyemi, Debasish Saha, Joseph O. Oundo, John B. Ochieng, Richard Omore, O. Colin Stine, David Wang, and Lori R. Holtz

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HIF-1α mediates isoflurane-induced vascular protection in subarachnoid hemorrhage, Eric Milner, Andrew W. Johnson, James W. Nelson, Michael D. Harries, Jeffrey M. Gidday, Byung Hee Han, and Gregory J. Zipfel

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Neurocognitive outcomes and school performance in solid tumor cancer survivors lacking therapy to the central nervous system, Caroline Mohrmann, Jennifer Henry, Marnie Hauff, and Robert J. Hayashi

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Revised American Thyroid Association guidelines for the management of medullary thyroid carcinoma, Jeffrey F. Moley and et al

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Binocular Goggle Augmented Imaging and Navigation System provides real-time fluorescence image guidance for tumor resection and sentinel lymph node mapping, Suman B. Mondal, Shengkui Gao, Nan Zhu, Gail P. Sudlow, Kexian Liang, Avik Som, Walter J. Akers, Ryan C. Fields, Julie Margenthaler, Rongguang Liang, Viktor Gruev, and Samuel Achilefu

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Gut resistome development in healthy twin pairs in the first year of life, Aimee M. Moore, Sara Ahmadi, Sanket Patel, Molly K. Gibson, Bin Wang, Malick I. Ndao, Elena Deych, William Shannon, Phillip I. Tarr, Barbara B. Warner, and Gautam Dantas

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Cerebrospinal fluid levels of amyloid precursor protein are associated with ventricular size in post-hemorrhagic hydrocephalus of prematurity, Diego M. Morales, Richard Holubkov, Terri E. Inder, Haejun C. Ahn, Deanna Mercer, Rakesh Rao, James P. McAllister II, David M. Holtzman, and David D. Limbrick Jr.

Large-scale genomics unveil polygenic architecture of human cortical surface area, John Morris, Marc Raichle, Davie Holtzman, Nigel J. Cairns, Erin Householder, Lisa Taylor-Reinwald, and et al.

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Multi-platform profiling of over 2000 sarcomas: Identification of biomarkers and novel therapeutic targets, Sujana Movva, Wenhsiang Wen, Wangjuh Chen, Sherri Z. Millis, Zoran Gatalica, Sandeep Reddy, Margaret von Mehren, and Brian A. Van Tine

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Sleep, circadian rhythms, and the pathogenesis of Alzheimer Disease., Erik S. Musiek, David D. Xiong, and David M. Holtzman

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Using whole-genome sequences of the LG/J and SM/J inbred mouse strains to prioritize quantitative trait genes and nucleotides, Igor Nikolskiy, Donald F. Conrad, Sung Chun, Justin C. Fay, James M. Cheverud, and Heather A. Lawson

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ERK2 alone drives inflammatory pain but cooperates with ERK1 in sensory neuron survival, Daniel E. O'Brien, Benedict J. Alter, Maiko Satomoto, Clinton D. Morgan, Steve Davidson, Sherri K. Vogt, Megan E. Norman, Graydon B. Gereau, Joseph A. Demaro III, Gary E. Landreth, Judith P. Golden, and Robert W. Gereau IV

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Deletion of macrophage vitamin D receptor promotes insulin resistance and monocyte cholesterol transport to accelerate atherosclerosis in mice, Jisu Oh, Amy E. Riek, Isra Darwech, Katsuhiko Funai, JianSu Shao, Kathleen Chin, Oscar L. Sierra, Geert Carmeliet, Richard E. Ostlund Jr., and Carlos Bernal-Mizrachi

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Full thickness macular hole case after intravitreal aflibercept treatment, Yuji Oshima, Rajendra S. Apte, Shintaro Nakao, Shigeo Yoshida, and Tatsuro Ishibashi

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Fmrp targets or not: Long, highly brain-expressed genes tend to be implicated in autism and brain disorders, Rebecca L. Ouwenga and Joseph Dougherty

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Developing educational competencies for dissemination and implementation research training programs: An exploratory analysis using card sorts, Margaret Padek, Graham Colditz, Maureen Dobbins, Nikolas Koscielniak, Enola K. Proctor, Anne E. Sales, and Ross C. Brownson

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Streptococcus pyogenes malate degradation pathway links pH regulation and virulence, Elyse Paluscio and Michael G. Caparon

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Detailed phenotypic and molecular analyses of genetically modified mice generated by CRISPR-Cas9-mediated editing, Bijal A. Parikh, Diana L. Beckman, Swapneel J. Patel, J. Michael White, and Wayne M. Yokoyama

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Delayed surgical intervention in central cord syndrome with cervical stenosis, Moon S. Park, Seong-Hwan Moon, Hwan-Mo Lee, Tae-Hwan Kim, Jae K. Oh, Bo-Kyung Suh, Seung J. Lee, and K. D. Riew

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The nutrition transition in Colombia over a decade: A novel household classification system of anthropometric measures, Diana C. Parra, Lora Iannotti, Luis F. Gomez, Helena Pachon, Debra Haire-Joshu, Olga L. Sarmiento, Anne Sebert Kuhlmann, and Ross C. Brownson

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Travel advice for the immunocompromised traveler: prophylaxis, vaccination, and other preventive measures, Rupa R. Patel, Stephen Y. Liang, Pooja Koolwal, and Frederick Matthew Kuhlmann

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Comparison of chromogenic media for recovery of carbapenemase-producing enterobacteriaceae (CPE) and evaluation of CPE prevalence at a tertiary care academic medical center, Morgan A. Pence, Tiffany Hink, and Carey-Ann D. Burnham

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Perilesional edema in radiation necrosis reflects axonal degeneration, Carlos J. Perez-Torres, Liya Yuan, Robert E. Schmidt, Keith M. Rich, Joseph JH Ackerman, and Joel R. Garbow

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Functional characterization of bacteria isolated from ancient Arctic soil exposes diverse resistance mechanisms to modern antibiotics, Gabriel G. Perron, Lyle Whyte, Peter J. Turnbaugh, Jacqueline Goordial, William P. Hanage, Gautam Dantas, and Michael M. Desai

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Active displacement of RecA filaments by UvrD translocase activity, Vessela Petrova, Stefanie H. Chen, Eileen T. Molzberger, Eric Tomko, Sindhu Chitteni-Pattu, Haifeng Jia, Yerdos Ordabayev, Timothy M. Lohman, and Michael M. Cox

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Peptide-siRNA nanotherapeutics in arthritis, Christine T N Pham, Hua Pan, and Samuel A. Wickline

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The number of discharge medications predicts thirty-day hospital readmission: A cohort study, David Picker, Kevin Heard, Thomas C. Bailey, Nathan R. Martin, Gina N. LaRossa, and Marin H. Kollef

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Adrenocortical zonation, renewal, and remodeling, Marjut Pihlajoki, Julia Dorner, Rebecca S. Cochran, Markku Heikinheimo, and David B. Wilson

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Therapeutic hypothermia after out-of-hospital cardiac arrest in children, Jose A. Pineda and et al

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A cost-effectiveness analysis of a chemoresponse assay for treatment of patients with recurrent epithelial ovarian cancer, Victoria Plamadeala, Joseph L. Kelley, John K. Chan, Thomas C. Krivak, Michael J. Gabrin, Stacey L. Brower, Matthew A. Powell, Thomas J. Rutherford, and Robert L. Coleman

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Complete genome sequences of emm6 Streptococcus pyogenes JRS4 and parental strain D471, Gary C. Port, Elyse Paluscio, and Michael G. Caparon

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A murine Niemann-Pick C1 I1061T knock-In model recapitulates the pathological features of the most prevalent human disease allele, Maria Praggastis, Brett Tortelli, Jessie Zhang, Hideji Fujiwara, Rohini Sidhu, Anita Chacko, Zhouji Chen, Jean E. Schaffer, Daniel S. Ory, and et al

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Converging evidence for the neuroanatomic basis of combinatorial semantics in the angular gyrus, Amy R. Price, Michael F. Bonner, Jonathan E. Peelle, and Murray Grossman

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Identification of hematomas in mild traumatic brain injury using an index of quantitative brain electrical activity, Leslie S. Prichep, Rosanne Naunheim, Jeffrey Bazarian, W. Andrew Mould, and Daniel Hanley

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Sustainability of evidence-based healthcare: Research agenda, methodological advances, and infrastructure support, Enola Proctor, Douglas Luke, Annaliese Calhoun, Curtis McMillen, Ross Brownson, Stacey McCrary, and Margaret Padek

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Oropouche virus infection and pathogenesis are restricted by MAVs, IRF-3, IRF-7, and type I interferon signaling pathways in nonmyeloid cells, Jose Luiz Proenca-Modena, Renata Sesti-Costa, Amelia K. Pinto, Justin M. Richner, Helen M. Lazear, Tiffany Lucas, Jennifer L. Hyde, and Michael S. Diamond

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Accurate age classification of 6 and 12 month-old infants based on resting-state functional connectivity magnetic resonance imaging data, John R. Pruett Jr., Sridhar Kandala, Sarah Hoertel, Abraham Z. Snyder, Tomoyuki Nishino, Nico U.F. Dosenbach, Binyam Nardos, Babatunde Adeyemo, Kelly N. Botteron, Robert C. McKinstry, John N. Constantino, Steven E. Petersen, Bradley L. Schlaggar, and et al

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Real-Time PCR assay for detection and differentiation of Shiga toxin-producing Escherichia coli from clinical samples, Xuan Qin, Eileen J. Klein, Emmanouil Galanakis, Anita A. Thomas, Jennifer R. Stapp, Shannon Rich, Anne Marie Buccat, and Phillip I. Tarr

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Influence of physical education on moderate-to-vigorous physical activity of urban public school children in St. Louis, Missouri, 2011–2014, Susan B. Racette, Tiffany C. Dill, M. Leanne White, Jacqueline C. Castillo, Mary L. Uhrich, Cindi L. Inman, Nicholas C. DuPont, and B. Ruth Clark

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CarD stabilizes mycobacterial open complexes via a two-tiered kinetic mechanism, Jayan Rammohan, Ana Ruiz Manzano, Ashley L. Garner, Christina L. Stallings, and Eric A. Galburt

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Using segmented regression analysis of interrupted time series data to assess colonoscopy quality outcomes of a web-enhanced implementation toolkit to support evidence-based practices for bowel preparation: A study protocol, Alex T. Ramsey, Julia Maki, Beth Prusaczyk, Yan Yan, Jean Wang, and Rebecca Lobb

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Provider-agency fit in substance abuse treatment organizations: Implications for learning climate, morale, and evidence-based practice implementation, Alex T. Ramsey, Carissa van den Berk-Clark, and David A. Patterson Silver Wolf (Adelvunegv Waya)

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Seminoma presenting as renal mass, inferior vena caval thrombus, and regressed testicular mass, Valary T. Raup, Michael H. Johnson, Jonathan R. Weese, Ian S. Hagemann, Stephen D. Marshall, and Steven B. Brandes

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Association of functional polymorphisms from brain-derived neurotrophic factor and serotonin-related genes with depressive symptoms after a medical stressor in older adults, Kerri S. Rawson, David Dixon, Petra Nowotny, William M. Ricci, Ellen F. Binder, Thomas Rodebaugh, Leah Wendleton, Peter Dore, and Eric J. Lenze

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Correlation of foraminal area and response to cervical nerve root injections, Wilson Z. Ray, Syed Akbari, Lubdha M. Shah, and Erica Bisson

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Fetal-to-maternal signaling to initiate parturition, Erin L. Reinl and Sarah K. England

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IFIT1 differentially interferes with translation and replication of alphavirus genomes and promotes induction of type I interferon, Josephine M. Reynaud, Dal Young Kim, Svetlana Atasheva, Aliaksandra Rasalouskaya, James P. White, Michael S. Diamond, Scott C. Weaver, Elena I. Frolova, and Ilya Frolov

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Variability in the practice of fertility preservation for patients with cancer, Kasey A. Reynolds, Natalia M. Grindler, Julie S. Rhee, Amber R. Cooper, Valerie S. Ratts, Kenneth R. Carson, and Emily S. Jungheim

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What's new in Orthopaedic Trauma, William M. Ricci, James C. Black, Christopher M. McAndrew, and Michael J. Gardner

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A genetic risk score combining 32 SNPs is associated with body mass index and improves obesity prediction in people with major depressive disorder, John Rice and et al

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Familiality and SNP heritability of age at onset and episodicity in major depressive disorder, J. P. Rice and et al

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Sexual selection and cancer biology, Joshua B. Rubin

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Graded gene expression changes determine phenotype severity in mouse models of CRX-associated retinopathies, Philip A. Ruzycki, Nicholas M. Tran, Vladimir J. Kefalov, Alexander V. Kolesnikov, and Shiming Chen

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Novel genetic locus implicated for HIV-1 acquisition with putative regulatory links to HIV replication and infectivity: A genome-wide association study, Nancy L. Saccone, John P. Rice, Laura J. Bierut, and et al

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Examination of the enterotoxigenic Escherichia coli population structure during human infection, Jason W. Sahl, Jeticia R. Sistrunk, Claire M. Fraser, Erin Hine, Nabilah Baby, Yasmin Begum, Qingwei Luo, Alaullah Sheikh, Firdausi Qadri, James M. Fleckenstein, and David A. Rasko

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Secreted CLCA1 modulates TMEM16A to activate Ca2+-dependent chloride currents in human cells, Monica Sala-Rabanal, Zeynep Yurtsever, Colin G. Nichols, and Tom J. Brett

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Use of culturally focused theoretical frameworks for adapting diabetes prevention programs: A qualitative review, Vetta L. Sanders Thompson, Michelle Johnson-Jennings, Ana A. Baumann, and Enola Proctor

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Are movement disorders and sensorimotor injuries pathologic synergies? When normal multi-joint movement synergies become pathologic, Marco Santello and Catherine E. Lang

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Sensitivity and kinetics of signal transmission at the first visual synapse differentially impact visually-guided behavior, Ignacio Sarria, Johan Pahlberg, Yan Cao, Alexander V. Kolesnikov, Vladimir J. Kefalov, Alapakkam P. Sampath, and Kirill A. Martemyanov

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Architectural and biochemical adaptations in skeletal muscle and bone following rotator cuff injury in a rat model, Eugene J. Sato, Megan L. Killian, Anthony J. Choi, Evie Lin, Alexander D. Choo, Ana E. Rodriguez-Soto, Chanteak T. Lim, Stavros Thomopoulos, Leesa M. Galatz, and Samuel R. Ward

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Deficiency of Prdm13, a dorsomedial hypothalamus-enriched gene, mimics age-associated changes in sleep quality and adiposity, Akiko Satoh, Cynthia S. Brace, Nick Rensing, and Shin-ichiro Imai

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Nab-paclitaxel-based compared to docetaxel-based induction chemotherapy regimens for locally advanced squamous cell carcinoma of the head and neck, Amy Schell, Jessica Ley, Ningying Wu, Kathryn Trinkaus, Tanya Marya Wildes, Loren Michel, Wade Thorstad, Hiram Gay, James Lewis, Jason Rich, Jason Diaz, Randal C. Paniello, Brian Nussenbaum, and Douglas R. Adkins

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The mitochondria in diabetic heart failure: From pathogenesis to therapeutic promise, Joel D. Schilling

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Autosomal dominant Alzheimer disease: A unique resource to study CSF biomarker changes in preclinical AD, Suzanne Elizabeth Schindler and Anne M. Fagan

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The utility of Google Trends data to examine interest in cancer screening, Mario Schootman, Aroona H. Toor, Patricia A. Cavazos-Rehg, Donna B. Jeffe, Amy McQueen, J. Eberth, and Nicholas O. Davidson

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Uropathogenic Escherichia coli superinfection enhances the severity of mouse bladder infection, Drew J. Schwartz, Matt S. Conover, Thomas J. Hannan, and Scott J. Hultgren

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REDHORSE-REcombination and Double crossover detection in Haploid Organisms using next-geneRation SEquencing data, Jahangheer S. Shaik, Asis Khan, Stephen M. Beverley, and L. David Sibley

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Selective blockade of interferon-α and -β reveals their non-redundant functions in a mouse model of West Nile virus infection, Kathleen C. F. Sheehan, Helen M. Lazear, Michael S. Diamond, and Robert D. Schreiber