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Submissions from 2022

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Genomic and transcriptomic somatic alterations of hepatocellular carcinoma in non-cirrhotic livers, Zachary L Skidmore, Jason Kunisaki, Yiing Lin, Kelsy C Cotto, Erica K Barnell, Jasreet Hundal, Kilannin Krysiak, Vincent Magrini, Lee Trani, Jason R Walker, Robert Fulton, Elizabeth M Brunt, Christopher A Miller, Richard K Wilson, Elaine R Mardis, Malachi Griffith, William Chapman, and Obi L Griffith

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Somatic Dnmt3a inactivation leads to slow, canonical DNA methylation loss in murine hematopoietic cells, Amanda M Smith, Angela M Verdoni, Haley J Abel, David Y Chen, Shamika Ketkar, Elizabeth R Leight, Christopher A Miller, and Timothy J Ley

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Somatic Dnmt3a inactivation leads to slow, canonical DNA methylation loss in murine hematopoietic cells, Amanda M. Smith, Angela M. Verdoni, Haley J. Abel, David Y. Chen, Shamika Ketkar, Elizabeth R. Leight, Christopher A. Miller, and Timothy J. Ley

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Opportunities to improve policy dissemination by tailoring communication materials to the research priorities of legislators, Natalie R Smith, Stephanie Mazzucca, Marissa G Hall, Kristen Hassmiller Lich, Ross C Brownson, and Leah Frerichs

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Validation of blood-based transcriptomic circadian phenotyping in older adults, S Kendall Smith, Peter Tran, Katherine A Madden, Jill Boyd, Rosemary Braun, Erik S Musiek, and Yo-El S Ju

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The Emotional Word-Emotional Face Stroop task in the ABCD study: Psychometric validation and associations with measures of cognition and psychopathology, Harry R Smolker, Kai Wang, Monica Luciana, James M Bjork, Raul Gonzalez, Deanna M Barch, Erin C McGlade, Roselinde H Kaiser, Naomi P Friedman, John K Hewitt, and Marie T Banich

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When REBOA grows wings: Resuscitative endovascular balloon occlusion of the aorta to facilitate aeromedical transport, Jason A Snyder, Douglas J E Schuerer, Grant V Bochicchio, and Mark H Hoofnagle

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Intracellular connections between basal bodies promote the coordinated behavior of motile cilia, Adam W J Soh, Louis G Woodhams, Anthony D Junker, Cassidy M Enloe, Benjamin E Noren, Adam Harned, Christopher J Westlake, Kedar Narayan, John S Oakey, Philip V Bayly, and Chad G Pearson

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JIB-04 has broad-spectrum antiviral activity and inhibits SARS-CoV-2 replication and coronavirus pathogenesis, Juhee Son, Shimeng Huang, Qiru Zeng, Traci L Bricker, James Brett Case, Ruochen Zang, Zhuoming Liu, Tamarand L Darling, Jian Xu, Houda H Harastani, Maria Florencia Gomez Castro, Hinissan P Kohio, Gaopeng Hou, Paul W Rothlauf, Adam L Bailey, Steven L Brody, Sean P J Whelan, Michael S Diamond, Adrianus C M Boon, Siyuan Ding, and et al

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Racial and ethnic minorities have a lower prevalence of airflow obstruction than non-Hispanic Whites, Akshay Sood, Hans Petersen, Congjian Liu, Orrin Myers, Xin Wang Shore, Bobbi A Gore, Rodrigo Vazquez-Guillamet, Linda S Cook, Paula Meek, and Yohannes Tesfaigzi

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Association of endocrine therapy initiation timeliness with adherence and continuation in low-income women with breast cancer, Nikita Sood, Ying Liu, Min Lian, Tracy Greever-Rice, Jill Lucht, Chester Schmaltz, and Graham A Colditz

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IL-1 reprogramming of adult neural stem cells limits neurocognitive recovery after viral encephalitis by maintaining a proinflammatory state, Allison L Soung, Veronica A Davé, Charise Garber, Eric D Tycksen, Lauren L Vollmer, and Robyn S Klein

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COVID-19 induces CNS cytokine expression and loss of hippocampal neurogenesis, Allison L Soung, Abigail Vanderheiden, Xiaoping Jiang, Traci Bricker, Adrianus C M Boon, Robyn S Klein, and et al.

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22q11.2 Deletion Syndrome - A series of patients with midline skull base defects, Spencer S. Souza, Lia Jacobson, Dylan Chan, Anna Meyer, Jarod L. Roland, and Kimberly Luu

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De novo serine biosynthesis from glucose predicts sex-specific response to antifolates in non-small cell lung cancer cell lines, Jasmin Sponagel, Siddhartha Devarakonda, Joshua B Rubin, Jingqin Luo, and Joseph E Ippolito

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Sex differences in brain tumor glutamine metabolism reveal sex-specific vulnerabilities to treatment, Jasmin Sponagel, Jill K Jones, Cheryl Frankfater, Shanshan Zhang, Olivia Tung, Kevin Cho, Kelsey L Tinkum, Hannah Gass, Elena Nunez, Gary J Patti, Jingqin Luo, Joshua B Rubin, Joseph E Ippolito, and et al.

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Inhibiting ACK1-mediated phosphorylation of C-terminal Src kinase counteracts prostate cancer immune checkpoint blockade resistance, Dhivya Sridaran, Surbhi Chouhan, Kiran Mahajan, Arun Renganathan, Cody Weimholt, Shambhavi Bhagwat, Melissa Reimers, Eric H Kim, Manish K Thakur, Muhammad A Saeed, Russell K Pachynski, Markus A Seeliger, W Todd Miller, Felix Y Feng, and Nupam P Mahajan

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Advice to clinicians on communication from adolescents and young adults with cancer and parents of children with cancer, Meghana Srinivas, Erica C Kaye, Lindsay J Blazin, Justin N Baker, Jennifer W Mack, James M DuBois, and Bryan A Sisk

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Antibodies targeting the neuraminidase active site inhibit influenza H3N2 viruses with an S245N glycosylation site, Daniel Stadlbauer, Ali H Ellebedy, and et al.

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Directed mutational scanning reveals a balance between acidic and hydrophobic residues in strong human activation domains, Max V Staller, Eddie Ramirez, Sanjana R Kotha, Alex S Holehouse, Rohit V Pappu, and Barak A Cohen

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Infantile-onset Pompe disease complicated by sickle cell anemia: Case report and management considerations, Rodrigo Tzovenos Starosta, Ying-Chen Claire Hou, Katelyn Leestma, Prapti Singh, Luke Viehl, Linda Manwaring, Jorge Luis Granadillo, Molly C Schroeder, Jamie N Colombo, Halana Whitehead, Patricia Irene Dickson, Monica L Hulbert, and Hoanh Thi Nguyen

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Manufacturing-dependent change in biological activity of the TLR4 agonist GSK1795091 and implications for lipid A analog development, Neeltje Steeghs, Haeseong Park, and et al.

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Semaphorin-plexin signaling: From axonal guidance to a new X-linked intellectual disability syndrome, Jacqueline L Steele, Marwan S Shinawi, and et al.

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Implementing a new Emergency Department: A qualitative study of health professionals' change responses and perceptions, Nina Thórný Stefánsdóttir, Per Nilsen, Mette Bendtz Lindstroem, Ove Andersen, Byron J Powell, Tine Tjørnhøj-Thomsen, and Jeanette Wassar Kirk

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Left ventricular hypertrophy and biomarkers of cardiac damage and stress in aortic stenosis, Elliot J Stein, Nishath Quader, Alan Zajarias, Anna Vatterott, and et al

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Global variation in studies of articular cartilage procedures of the knee: A systematic review, R. Garrett Steinmetz, J. Jared Guth, Matthew J Matava, Matthew V Smith, and Robert H Brophy

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Ascertainment of vaccination status by self-report versus source documentation: Impact on measuring COVID-19 vaccine effectiveness, Meagan Stephenson, Jennie H Kwon, and et al

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A dual-center cohort study on the association between early deep sedation and clinical outcomes in mechanically ventilated patients during the COVID-19 pandemic: The COVID-SED study, Robert J Stephens, Erin M Evans, Michael J Pajor, Ryan D Pappal, Haley M Egan, Max Wei, Hunter Hayes, Jason A Morris, Nicholas Becker, Brian W Roberts, Marin H Kollef, Nicholas M Mohr, and Brian M Fuller

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Adverse events related to ultrasound-guided regional anesthesia performed by Emergency Physicians: Systematic review protocol, Sean P. Stickles, Deborah Shipley Kane, Chadd K. Kraus, Robert J. Strony, Enyo A. Ablordeppey, Michelle M. Doering, Daniel Theodoro, Jacques Simon Lee, and Christopher R. Carpenter

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Btla signaling in conventional and regulatory lymphocytes coordinately tempers humoral immunity in the intestinal mucosa, Caroline Stienne, Richard Virgen-Slane, Lisa Elmén, Marisol Veny, Sarah Huang, Jennifer Nguyen, Elizabeth Chappell, Mary Olivia Balmert, Jr-Wen Shui, Michelle A Hurchla, Mitchell Kronenberg, Scott N Peterson, Kenneth M Murphy, Carl F Ware, and John R Šedý

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Structural and molecular rationale for the diversification of resistance mediated by the Antibiotic_NAT family, Peter J Stogios, Emily Bordeleau, Zhiyu Xu, Tatiana Skarina, Elena Evdokimova, Sommer Chou, Luke Diorio-Toth, Alaric W D'Souza, Sanket Patel, Gautam Dantas, Gerard D Wright, and Alexei Savchenko

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Comparing antigenaemia- and microfilaraemia as criteria for stopping decisions in lymphatic filariasis elimination programmes in Africa, Wilma A. Stolk, Luc E. Coffeng, Fatorma K. Bolay, Obiora A. Eneanya, Peter U. Fischer, T. Déirdre Hollingsworth, Benjamin G. Koudou, Aboulaye Méité, Edwin Michael, Joaquin M. Prada, Rocio M. Caja Rivera, Swarnali Sharma, Panayiota Touloupou, Gary J. Weil, and Sake J. de Vlas

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Heart sparing radiotherapy techniques in breast cancer: A focus on deep inspiration breath hold, Hayley B Stowe, Neal D Andruska, Francisco Reynoso, Maria Thomas, and Carmen Bergom

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Genetic, epigenetic, and environmental mechanisms govern allele-specific gene expression, Celine L St Pierre, Juan F Macias-Velasco, Jessica P Wayhart, Li Yin, Clay F Semenkovich, and Heather A Lawson

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CSF Tau phosphorylation at Thr205 is associated with loss of white matter integrity in autosomal dominant Alzheimer disease, Jeremy F. Strain, Nicolas Barthelemy, Kanta Horie, Brian A. Gordon, Collin Kilgore, Andrew Aschenbrenner, Carlos Cruchaga, Chengjie Xiong, Nelly Joseph-Mathurin, Jason Hassenstab, Anne M. Fagan, Yan Li, Celeste M. Karch, Richard J. Perrin, Sarah B. Berman, Jasmeer P. Chhatwal, Neill R. Graff-Radford, Hiroshi Mori, Johannes Levin, James M. Noble, Ricardo Allegri, Peter R. Schofield, Daniel S. Marcus, David M. Holtzman, John C. Morris, Tammie L. S. Benzinger, Eric M. McDade, Randall J. Bateman, and Beau M. Ances

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Covariance-based vs. correlation-based functional connectivity dissociates healthy aging from Alzheimer disease, Jeremy F. Strain, Matthew R. Brier, Aaron Tanenbaum, Brian A. Gordon, John E. McCarthy, Aylin Dincer, Daniel S. Marcus, Richard J. Perrin, John C. Morris, Tammie L. S. Benzinger, Randall J. Bateman, Beau M. Ances, Abraham Z. Snyder, and et al.

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Molecular classification and biomarkers of clinical outcome in breast ductal carcinoma in situ: Analysis of TBCRC 038 and RAHBT cohorts, Siri H Strand, Deborah J Veis, Katherine DeSchryver, Jen Tappenden, Jingqin Luo, Shu Jiang, Graham A Colditz, and et al.

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Onasemnogene abeparvovec for presymptomatic infants with three copies of SMN2 at risk for spinal muscular atrophy: The Phase III SPR1NT trial, Kevin A Strauss, Craig M Zaidman, and et al

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Onasemnogene abeparvovec for presymptomatic infants with two copies of SMN2 at risk for spinal muscular atrophy type 1: The Phase III SPR1NT trial, Kevin A Strauss, Craig M Zaidman, and et al

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A novel computer adaptive word list memory test optimized for remote assessment: Psychometric properties and associations with neurodegenerative biomarkers in older women without dementia, Nikki H Stricker, John L Stricker, Aimee J Karstens, Jennifer R Geske, Julie A Fields, Jason Hassenstab, Christopher G Schwarz, Nirubol Tosakulwong, Heather J Wiste, Clifford R Jack, Kejal Kantarci, and Michelle M Mielke

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Tuft-cell-intrinsic and -extrinsic mediators of norovirus tropism regulate viral immunity, Madison S Strine, Mia Madel Alfajaro, Vincent R Graziano, Jaewon Song, Leon L Hsieh, Ryan Hill, Jun Guo, Kelli L VanDussen, Robert C Orchard, Megan T Baldridge, Sanghyun Lee, and Craig B Wilen

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Lifespan benefits for the combination of rapamycin plus acarbose and for captopril in genetically heterogeneous mice, Randy Strong, Kerry Kornfeld, and et al.

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Correlating electroconvulsive therapy response to electroencephalographic markers: Study protocol, Subha Subramanian, Alyssa K Labonte, Thomas Nguyen, Anhthi H Luong, Orlandrea Hyche, S Kendall Smith, R Edward Hogan, Nuri B Farber, Ben Julian A Palanca, MohammadMehdi Kafashan, and CET-REM Study Group

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Antibiotic-resistant organisms establish reservoirs in new hospital built environments and are related to patient blood infection isolates, Kimberley V Sukhum, Erin P Newcomer, Candice Cass, Meghan A Wallace, Caitlin Johnson, Jeremy Fine, Steven Sax, Margaret H Barlet, Carey-Ann D Burnham, Gautam Dantas, and Jennie H Kwon

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India's ban on antimicrobial fixed-dose combinations: Winning the battle, losing the war?, Giorgia Sulis, Richeek Pradhan, Anita Kotwani, and Sumanth Gandra

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Exposure to World Health Organization's AWaRe antibiotics and isolation of multidrug resistant bacteria: A systematic review and meta-analysis, Giorgia Sulis, Sena Sayood, Shashi Katukoori, Neha Bollam, Ige George, Lauren H. Yaeger, Miguel A. Chavez, Emmanuel Tetteh, Sindhu Yarrabelli, Celine Pulcini, Stephan Harbarth, Dominik Mertz, Mike Sharland, Lorenzo Moja, Benedikt Huttner, and Sumanth Gandra

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Evaluation of sensitivity to endocrine herapy index (SET2,3) for response to neoadjuvant endocrine therapy and longer-term breast cancer patient outcomes (Alliance Z1031), Vera J Suman, Lili Du, Tanya Hoskin, Meenakshi Anurag, Cynthia Ma, Isabelle Bedrosian, Kelly K Hunt, Matthew J Ellis, and W Fraser Symmans

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Essential functions of MLL1 and MLL2 in retinal development and cone cell maintenance, Chi Sun, Xiaodong Zhang, Philip A Ruzycki, and Shiming Chen

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Isolation of SARS-CoV-2 in viral cell culture in immunocompromised patients with persistently positive RT-PCR results, Abby Sung, Adam L Bailey, Henry B Stewart, David McDonald, Meghan A Wallace, Kate Peacock, Candace Miller, Kimberly A Reske, Caroline A O'Neil, Victoria J Fraser, Michael S Diamond, Carey-Ann D Burnham, Hilary M Babcock, and Jennie H Kwon

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Human NK cells confer protection against HIV-1 infection in humanized mice, Can M. Sungur, Qiankun Wang, Ayşe N. Ozantürk, Hongbo Gao, Aaron J. Schmitz, Marina Cella, Wayne M. Yokoyama, and Liang Shan

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Tumor-associated macrophages in multiple myeloma: Advances in biology and therapy, Jennifer Sun, Chaelee Park, Nicole Guenthner, Shannon Gurley, Luna Zhang, Berit Lubben, Ola Adebayo, Hannah Bash, Yixuan Chen, Mina Maksimos, Barbara Muz, and Abdel Kareem Azab

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Fracture healing is delayed in the absence of gasdermin-interleukin-1 signaling, Kai Sun, Chun Wang, Jianqiu Xiao, Michael D. Brodt, Luorongxin Yuan, Tong Yang, Yael Alippe, Huimin Hu, Dingjun Hao, Yousef Abu-Amer, Matthew J. Silva, Jie Shen, and Gabriel Mbalaviele

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The multifaceted mechanisms of malignant glioblastoma progression and clinical implications, Rui Sun and Albert H Kim

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Discovery and validation of dominantly inherited Alzheimer's disease mutations in populations from Latin America, Leonel Tadao Takada, Bhagyashri D Burgute, Ellen Ziegemeier, Jennifer Petranek, Carlos Cruchaga, Maria Victoria Fernández, Eric McDade, Randall J Bateman, Celeste M Karch, Jorge J Llibre-Guerra, and et al.

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Approaches to healthcare personnel exemption requests from coronavirus disease 2019 (COVID-19) vaccination: Results of a national survey, Thomas R Talbot, Susan E Beekmann, Hilary M Babcock, and Philip M Polgreen

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Sequencing of a Chinese tetralogy of Fallot cohort reveals clustering mutations in myogenic heart progenitors, Clara Sze Man Tang, Mimmi Mononen, Wai-Yee Lam, Sheng Chih Jin, Xuehan Zhuang, Maria-Mercè Garcia-Barcelo, Qiongfen Lin, Yujia Yang, Makoto Sahara, Elif Eroglu, Kenneth R. Chien, Haifa Hong, Paul Kwong Hang Tam, and Peter J. Gruber

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Generation of dual-gRNA library for combinatorial CRISPR screening of synthetic lethal gene pairs, Shan Tang, Xue Wu, Jinghui Liu, Qiongsi Zhang, Xinyi Wang, Shuai Shao, Birkan Gokbag, Kunjie Fan, Xiaoqi Liu, Fuhai Li, Lijun Cheng, and Lang Li

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Controversies in spine research: Organ culture versus in vivo models for studies of the intervertebral disc, Shirley N Tang, Andres F Bonilla, Nadeen O Chahine, Aimee C Colbath, Jeremiah T Easley, Sibylle Grad, Lisbet Haglund, Christine L Le Maitre, Victor Leung, Annette M McCoy, Devina Purmessur, Simon Y Tang, Stephan Zeiter, and Lachlan J Smith

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Hippocampal threat reactivity interacts with physiological arousal to predict PTSD symptoms, Büşra Tanriverdi, Stacey L House, Deanna M. Barch, and et al.

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Vascular endothelial-cadherin as a marker of endothelial injury in preclinical Alzheimer disease, Rawan Tarawneh, Rachel S Kasper, Jessie Sanford, Chia-Ling Phuah, Jason Hassenstab, and Carlos Cruchaga

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Enteric pathogen testing importance for children with acute gastroenteritis: A modified Delphi study, Gillian A M Tarr, Drew J Persson, Phillip I Tarr, and Stephen B Freedman

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Safety and efficacy of mass drug administration with a single-dose triple-drug regimen of albendazole + diethylcarbamazine + ivermectin for lymphatic filariasis in Papua New Guinea: An open-label, cluster-randomised trial, Livingstone Tavul, Kobie O'Brian, Gary J. Weil, Charles W. Goss, and et al

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Safety and efficacy of pembrolizumab in combination with acalabrutinib in advanced head and neck squamous cell carcinoma: Phase 2 proof-of-concept study, Matthew H Taylor, Courtney B Betts, Lauren Maloney, Eric Nadler, Alain Algazi, Michael J Guarino, John Nemunaitis, Antonio Jimeno, Priti Patel, Veerendra Munugalavadla, Lin Tao, Douglas Adkins, Jerome H Goldschmidt, Ezra E W Cohen, and Lisa M Coussens

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Totally percutaneous endovascular repair for ruptured abdominal aortic aneurysms, Shirli Tay, Mohamed S Zaghloul, Mehreen Shafqat, Chao Yang, Kshitij A Desai, Gayan De Silva, Luis A Sanchez, and Mohamed A Zayed

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Predicting postoperative troponin in patients undergoing elective hip or knee arthroplasty: A comparison of five cardiac risk prediction tools, Merih T Tesfazghi, Anne R Bass, Noor Al-Hammadi, Scott C Woller, Scott M Stevens, Charles S Eby, Mitchell G Scott, Lindsey Snyder, Troy S Wildes, and Brian F Gage

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Public health information seeking, trust, and COVID-19 prevention behaviors: Cross-sectional study, Emmanuel Kwabena Tetteh, Todd Combs, Elvin Hsing Geng, and Virginia Ruth McKay

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Noninvasive testing and surrogate markers in invasive fungal diseases, George R Thompson, Andrej Spec, and et al.

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Maternal obesogenic diet enhances cholestatic liver disease in offspring, Michael D Thompson, Holly Hinrichs, Austin Faerber, Phillip I Tarr, and Nicholas O Davidson

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Selective whole-genome amplification as a tool to enrich specimens with low Treponema pallidum genomic DNA copies for whole-genome sequencing, Charles M Thurlow, Sandeep J Joseph, Lilia Ganova-Raeva, Samantha S Katz, Lara Pereira, Cheng Chen, Alyssa Debra, Kendra Vilfort, Kimberly Workowski, Stephanie E Cohen, Hilary Reno, Yongcheng Sun, Mark Burroughs, Mili Sheth, Kai-Hua Chi, Damien Danavall, Susan S Philip, Weiping Cao, Ellen N Kersh, and Allan Pillay

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Impaired mitophagy in Sanfilippo A mice causes hypertriglyceridemia and brown adipose tissue activation, Miguel Tillo, Patricia I Dickson, and et al.

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Predictors of humoral response to SARS-CoV-2 mRNA vaccine BNT162b2 in patients receiving maintenance dialysis, Li Tingting, Sumanth Gandra, Kimberly A. Reske, Margaret A. Olsen, Silvana Bommarito, Candace Miller, Karl G. Hock, Claire A. Ballman, Christina Su, Na Le Dang, Jennie H. Kwon, David K. Warren, Victoria J. Fraser, and Christopher W. Farnsworth

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Innexin function dictates the spatial relationship between distal somatic cells in the Caenorhabditis elegans gonad without impacting the germline stem cell pool, Theadora Tolkin, Ariz Mohammad, Todd A Starich, Ken C Q Nguyen, David H Hall, Tim Schedl, E Jane Albert Hubbard, and David Greenstein

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Distributed learning for heterogeneous clinical data with application to integrating COVID-19 data across 230 sites, Jiayi Tong, Chongliang Luo, Md Nazmul Islam, Natalie E Sheils, John Buresh, Mackenzie Edmondson, Peter A Merkel, Ebbing Lautenbach, Rui Duan, and Yong Chen

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Current understanding of osteoarthritis pathogenesis and relevant new approaches, Liping Tong, Huan Yu, Xingyun Huang, Jie Shen, Guozhi Xiao, Lin Chen, Huaiyu Wang, Lianping Xing, and Di Chen

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Digital interventions to address mental health needs in colleges: Perspectives of student stakeholders, Naira Topooco, Lauren A Fowler, Ellen E Fitzsimmons-Craft, Bianca DePietro, Melissa M Vázquez, Marie-Laure Firebaugh, Peter Ceglarek, Grace Monterubio, Michelle G Newman, Daniel Eisenberg, Denise E Wilfley, and C Barr Taylor

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Driving performance in older adults: Current measures, findings, and implications for roadway safety, Robert Toups, Theresa J Chirles, Johnathon P Ehsani, Jeffrey P Michael, John P K Bernstein, Matthew Calamia, Thomas D Parsons, David B Carr, and Jeffrey N Keller

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Establishment of novel neuroendocrine carcinoma patient-derived xenograft models for receptor peptide-targeted therapy, Catherine G Tran, Jacqueline L Mudd, Ramaswamy Govindan, Paul F Cliften, and Ryan C Fields

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Association of multidimensional poverty with dementia in adults aged 50 years or older in South Africa, Jean-Francois Trani, Jacqueline Moodley, May Thu Thu Maw, and Ganesh M. Babulal

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An evaluation of patient-reported outcomes in sickle cell disease within a conceptual model., Marsha J Treadwell, Swapandeep Mushiana, Sherif M Badawy, Liliana Preiss, Allison A King, Barbara Kroner, Yumei Chen, Jeffrey Glassberg, Victor Gordeuk, Nirmish Shah, Angela Snyder, Theodore Wun, and Sickle Cell Disease Implementation Consortium (SCDIC)

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Impact of consensus guidelines for breast-conserving surgery in patients with ductal carcinoma in situ, Abigail Tremelling, Rebecca L Aft, Amy E Cyr, William E Gillanders, Katherine Glover-Collins, Virginia Herrmann, and Julie A Margenthaler

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Association of prenatal exposure to early-life adversity with neonatal brain volumes at birth, Regina L Triplett, Rachel E Lean, Amisha Parikh, J Philip Miller, Dimitrios Alexopoulos, Sydney Kaplan, Dominique Meyer, Christopher Adamson, Tara A Smyser, Cynthia E Rogers, Deanna M Barch, Barbara Warner, Joan L Luby, and Christopher D Smyser

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The power of partnerships: State public health department multisector collaborations in major chronic disease programme areas in the United States, Edward Tsai, Peg Allen, Louise Farah Saliba, and Ross C Brownson

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The past, present, and future of a human T-cell leukemia virus type 1 vaccine, Joshua J Tu, Victoria Maksimova, Lee Ratner, and Amanda R Panfil

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Complete genome sequence of the uropathogenic methicillin-resistant Staphylococcus aureus strain MRSA-1369, Hasan Tükenmez, Taylor M Nye, Mari Bonde, Michael G Caparon, Fredrik Almqvist, Scott J Hultgren, and Jörgen Johansson

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Dysosteosclerosis: Clinical and radiological evolution reflecting genetic heterogeneity, Serap Turan, Steven Mumm, Ceren Alavanda, Betul Sare Kaygusuz, Busra Gurpinar Tosun, Ahmet Arman, Margaret Huskey, Tulay Guran, Shenghui Duan, Abdullah Bereket, and Michael P Whyte

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Dysregulation of the leukocyte signaling landscape during acute COVID-19, Isaiah R. Turnbull, Anja Fuchs, Kenneth E. Remy, Michael P. Kelly, Elfaridah P. Frazier, Sarbani Ghosh, Shin-Wen Chang, Monty B. Mazer, Annie Hess, Jennifer M. Leonard, Mark H. Hoofnagle, Marco Colonna, and Richard S. Hotchkiss

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The clinical cell-cycle risk (CCR) score is associated with metastasis after radiation therapy and provides guidance on when to forgo combined androgen deprivation therapy with dose-escalated radiation, Jonathan Tward, Hiram A. Gay, Jeff Michalski, and et al.

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Identification of gut bacteria such as Lactobacillus johnsonii that disseminate to systemic tissues of wild type and MyD88-/- mice, Sreeram Udayan, Panagiota Stamou, Fiona Crispie, Ana Hickey, Alexandria N Floyd, Chyi-Song Hsieh, Paul D Cotter, Orla O'Sullivan, Silvia Melgar, Paul W O'Toole, Rodney D Newberry, Valerio Rossini, and Ken Nally

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Recurrent transcriptional responses in AML and MDS patients treated with decitabine, Pawan Upadhyay, Jeremy Beales, Nakul M Shah, Agata Gruszczynska, Christopher A Miller, Allegra A Petti, Sai Mukund Ramakrishnan, Daniel C Link, Timothy J Ley, and John S Welch

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Transplant outcomes after CPX-351 vs 7 + 3 in older adults with newly diagnosed high-risk and/or secondary AML, Geoffrey L Uy, Laura F Newell, Tara L Lin, Stuart L Goldberg, Matthew J Wieduwilt, Robert J Ryan, Stefan Faderl, and Jeffrey E Lancet

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Combining plasma extracellular vesicle Let-7b-5p, miR-184 and circulating miR-22-3p levels for NSCLC diagnosis and drug resistance prediction, G P Vadla, B Daghat, N Patterson, V Ahmad, G Perez, A Garcia, Y Manjunath, J T Kaifi, G Li, and C Y Chabu

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Ceftriaxone resistance and adequacy of initial antibiotic therapy in community onset bacterial pneumonia, Richard F Van Besien, Nicholas Hampton, Scott T Micek, and Marin H Kollef

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Neuroinflammation and COVID-19, Abigail Vanderheiden and Robyn S. Klein

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StrainGE: A toolkit to track and characterize low-abundance strains in complex microbial communities, Lucas R van Dijk, Bruce J Walker, Timothy J Straub, Colin J Worby, Alexandra Grote, Henry L Schreiber 4th, Christine Anyansi, Amy J Pickering, Scott J Hultgren, Abigail L Manson, Thomas Abeel, and Ashlee M Earl

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Convection enhanced delivery of the oncolytic adenovirus Delta24-RGD in patients with recurrent GBM: A phase I clinical trial including correlative studies, Erik H P van Putten, David T Curiel, and et al

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Ubiquitin variants potently inhibit SARS-CoV-2 PLpro and viral replication via a novel site distal to the protease active site, Vera J. E. van Vliet, Nitin Sharma, Safder S. Ganaie, Gaya K. Amarasinghe, and et al

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Homeostatic interferon-lambda response to bacterial microbiota stimulates preemptive antiviral defense within discrete pockets of intestinal epithelium, Jacob A. Van Winkle, Stefan T. Peterson, Elizabeth A. Kennedy, Michael J. Wheadon, Harshad Ingle, Chandni Desai, Rachel Rodgers, David A. Constant, Austin P. Wright, Lena Li, Maxim N. Artyomov, Sanghyun Lee, Megan T. Baldridge, and Timothy J. Nice

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Antimicrobial stewardship for sepsis in the intensive care unit: Survey of critical care and infectious diseases physicians, M Cristina Vazquez Guillamet, Jason P Burnham, Maria Pérez, Marin H Kollef, Constantine A Manthous, and Donna B Jeffe

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Uncertainty analysis of chest X-ray lung height measurements and size matching for lung transplantation, Rodrigo Vazquez Guillamet, Maria C. Vazquez Guillamet, Ashraf Rjob, Andrew Bierhals, Irene Bello, Alberto Jauregui Abularach, Laneshia Tague, Michael Wallendorf, Gary F. Marklin, Chad Witt, Derek E. Byers, Daniel Kreisel, Ruben Nava, Varun Puri, Ramsey Hachem, and Elbert P Trulock

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Hereditary alpha-tryptasemia modifies clinical phenotypes among individuals with congenital hypermobility disorders, Maribel Vazquez, Jack Chovanec, Jiwon Kim, Thomas DiMaggio, Joshua D Milner, Clair A Francomano, Christina A Gurnett, Marco Ritelli, Marina Colombi, and Jonathan J Lyons