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Submissions from 2016

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Adherence to pre-exposure prophylaxis for HIV prevention in a clinical setting, Madeline C. Montgomery, Catherine E. Oldenburg, Amy S. Nunn, Leandro Mena, Peter Anderson, Teri Lieger, Kenneth H. Mayer, Rupa Patel, Alexi Almonte, and Philip A. Chan

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Inflammatory biomarker score and cancer: A population-based prospective cohort study, Leavitt Morrison, Jari A. Laukkanen, Kimmo Ronkainen, Sudhir Kurl, Jussi Kauhanen, and Adetunji T. Toriola

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Changes in the plasma proteome at asymptomatic and symptomatic stages of autosomal dominant Alzheimer’s disease, Julia Muenchhoff, Anne Poljak, Anbupalam Thalamuthu, Veer B. Gupta, Pratishtha Chatterjee, Mark Raftery, Colin L. Masters, John C. Morris, Randall J. Bateman, Anne M. Fagan, Ralph N. Martins, and Perminder S. Sachdev

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Functional connectivity of the amygdala and subgenual cingulate during cognitive reappraisal of emotions in children with MDD history is associated with rumination, Eric R. Murphy, Deanna M. Barch, David Pagliaccio, Joan L. Luby, and Andy C. Belden

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Spotlight on ixazomib: Potential in the treatment of multiple myeloma, Barbara Muz, Rachel N. Ghazarian, Monica Ou, Micha J. Luderer, Hubert D. Kusdono, and Abdel K. Azab

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Type I interferon receptor deficiency in dendritic cells facilitates systemic murine norovirus persistence despite enhanced adaptive immunity, Timothy J. Nice, Lisa C. Osborne, Vesselin T. Tomov, David Artis, E. John Wherry, and Herbert W. Virgin

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Modification of claims-based measures improves identification of comorbidities in non-elderly women undergoing mastectomy for breast cancer: A retrospective cohort study, Katelin B. Nickel, Anna E. Wallace, David K. Warren, Kelly E. Ball, Daniel Mines, Victoria J. Fraser, and Margaret A. Olsen

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Behavioral weight loss treatment for youth treated with antipsychotic medications, Ginger E. Nicol, Rachel P. Kolko, Monica Mills, Thrudur Gunnarsdottir, MIchael D. Yingling, Julia A. Schweiger, Eric J. Lenze, John W. Newcomer, and Denise Wilfley

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Getting to more effective weight management in antipsychotic-treated youth: a survey of barriers and preferences, Ginger Nicol, Elizabeth Worsham, Debra Haire-Joshu, Alexis Duncan, Julia Schweiger, Michael Yingling, and Eric Lenze

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ATX-LPA 1 axis contributes to proliferation of chondrocytes by regulating fibronectin assembly leading to proper cartilage formation, Tatsuji Nishioka, Naoaki Arima, Kuniyuki Kano, Kotaro Hama, Eriko Itai, Hiroshi Yukiura, Ryoji Kise, Asuka Inoue, Seok-Hyung Kim, Lilianna Solnica-Krezel, Wouter H. Moolenaar, Jerold Chun, and Junken Aoki

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Incessant tachycardia in a patient with advanced heart failure and left ventricular assist device: What is the mechanism?, Amit Noheria, Siva K. Mulpuru, Peter A. Noseworthy, and Samuel J. Asirvatham

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CD4 receptor is a key determinant of divergent HIV-1 sensing by plasmacytoid dendritic cells, Meagan O'Brien, Olivier Manches, Craig Wilen, Ramya Gopal, Rumana Huq, Vernon Wu, Nicole Sunsen, and Nina Bhardwaj

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Cartilage-specific knockout of the mechanosensory ion channel TRPV4 decreases age-related osteoarthritis, Christopher J. O'Conor, Sendhilnathan Ramalingam, Nicole A. Zelenski, Halei C. Benefield, Isaura Rigo, Dianne Little, Chia-Lung Wu, Di Chen, Wolfgang Liedtke, Amy L. McNulty, and Farshid Guilak

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Mechanisms of Zika virus infection and neuropathogenesis, David Olagnier, Michela Muscolini, Carolyn B. Coyne, Michael S. Diamond, and John Hiscott

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The burden of Clostridium difficile infection: Estimates of the incidence of CDI from U.S. Administrative databases, Margaret A. Olsen, Yinong Young-Xu, Dustin Stwalley, Ciaran P. Kelly, Dale N. Gerding, Mohammed J. Saeed, Cedric Mahe, and Erik R. Dubberke

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A central line care maintenance bundle for the prevention of central line–associated bloodstream infection in non–intensive care unit settings, Caroline O'Neil, Kelly Ball, Helen Wood, Kathleen McMullen, Pamala Kremer, S. Reza Jafarzadeh, Victoria Fraser, and David Warren

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The value of early and comprehensive diagnoses in a human fetus with hydrocephalus and progressive obliteration of the aqueduct of Sylvius: Case Report, Eduardo Ortega, Rosa I. Munoz, Nelly Luza, Francisco Geurra, Monserrat Guerra, Karin Vio, Roberto Henzi, Jaime Jaque, Sara Rodriguez, James P. McAllister, and Esteban Rodriguez

Spinolaminar line test as a screening tool for C1 stenosis, Yasushi Oshima, Michael P. Kelly, Kwang-Sup Song, Moon Soo Park, Tapanut Chuntarapas, Katie D. Vo, Jin S. Yeom, Katsushi Takeshita, and K. Daniel Riew

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Atg5 Is essential for the development and survival of innate lymphocytes, Timothy E. O'Sulivan, Clair D. Geary, Orr-El Weizman, Theresa L. Geiger, Moritz Rapp, Gerald W. Dorn II, Michael Overholtzer, and Joseph C. Sun

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Quantitative autistic trait measurements index background genetic risk for ASD in Hispanic families, Joshua Page, John Nicholas Constantino, Katherine Zambrana, Eden Martin, Ilker Tunc, Yi Zhang, Anna Abbacchi, and Daniel Messinger

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Plasmodium falciparum histidine-rich protein II compromises brain endothelial barriers and may promote cerebral malaria pathogenesis, Priya Pal, Brian P. Daniels, Anna Oskman, Michael S. Diamond, Robyn S. Klein, and Daniel E. Goldberg

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Inhibition of DNA methyltransferases blocks mutant huntingtin-induced neurotoxicity, Yanchun Pan, Takuji Daito, Yo Sasaki, Yong Hee Chung, Xiaoyun Xing, Santhi Pondugula, S. Joshua Swamidass, Ting Wang, Albert H. Kim, and Hiroko Yano

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Urinary metabolomics identifies a molecular correlate of interstitial cystitis/bladder pain syndrome in a Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network Cohort, Kaveri S. Parker, Jan R. Crowley, Alisa J. Stephens-Shields, Adrie van Bokhoven, M. Scott Lucia, H. Henry Lai, Gerald L. Andriole, Thomas M. Hooton, Chris Mullins, and Jeffrey P. Henderson

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Anthropometric factors and thyroid cancer risk by histological subtype: pooled analysis of 22 prospective studies, Yikyung Park and et al

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Case report: Severe cutaneous leishmaniasis in a human immunodeficiency virus patient coinfected with Leishmania braziliensis and its endosymbiotic virus, Laurent Parmentier, Alexia Cusini, Norbert Müller, Haroun Zangger, Mary-Anne Hartley, Chantal Desponds, Patrik Castiglioni, Patrick Dubach, Catherine Ronet, Stephen M. Beverley, and Nicolas Fasel

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Familial influences on the full range of variability in attention and activity levels during adolescence: A longitudinal twin study, Chun-Zi Peng, Julia D. Grant, Andrew C. Heath, Angela M. Reiersen, Richard C. Mulligan, and Andrey P. Anokhin

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Clinical and genetic features of cervical dystonia in a large multicenter cohort, Joel S. Perlmutter, Laura J. Wright, and et al

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Genomic profiling of murine mammary tumors identifies potential personalized drug targets for p53-deficient mammary cancers, Adam D. Pfefferle, Yash N. Agrawal, Daniel C. Koboldt, Krishna L. Kanchi, Jason I. Herschkowitz, Elaine R. Mardis, Jeffrey M. Rosen, and Charles M. Perou

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Autofluorescence as a measure of senescence in C. elegans: Look to red, not blue or green, Zachary Pincus, Travis C. Mazer, and Frank J. Slack

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Axonal growth arrests after an increased accumulation of Schwann cells expressing senescence markers and stromal cells in acellular nerve allografts, Louis H. Poppler, Xueping Ee, Lauren Schellhardt, Gwendolyn M. Hoben, Deng Pan, Daniel A. Hunter, Ying Yan, Amy M. Moore, Alison K. Snyder-Warwick, Sheila A. Stewart, Susan E. Mackinnon, and Matthew D. Wood

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Diabetes status and being up-to-date on colorectal cancer screening, 2012 Behavioral Risk Factor Surveillance System, Nancy R. Porter, Jan M. Eberth, Marsha E. Samson, Oralia Garcia-Dominic, Eugene J. Lengerich, and Mario Schootman

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Pten cell autonomously modulates the hematopoietic stem cell response to inflammatory cytokines, Shaina N. Porter, Andrew S. Cluster, Robert A.J. Signer, Jenna Voigtmann, Darlene A. Monlish, Laura G. Schuettpelz, and Jeffrey A. Magee

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p53 deficiency linked to B cell translocation gene 2 (BTG2) loss enhances metastatic potential by promoting tumor growth in primary and metastatic sites in patient-derived xenograft (PDX) models of triple-negative breast cancer, Emily Powell, Jiansu Shao, Yuan Yuan, Hsiang-Chun Chen, Shirong Cai, Gloria V. Echeverria, Nipun Mistry, Keith F. Decker, Christopher Schlosberg, Kim-Anh Do, John R. Edwards, Han Liang, David Piwnica-Worms, and Helen Piwnica-Worms

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Causal evidence for a mechanism of semantic integration in the angular gyrus as revealed by high-definition transcranial direct current stimulation, Amy Rose Price, Jonathan E. Peelle, Michael F. Bonner, Murray Grossman, and Roy H. Hamilton

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A review of policy dissemination and implementation research funded by the National Institutes of Health, 2007–2014, Jonathan Purtle, Rachel Peters, and Ross Brownson

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Direct hospital cost of outcome pathways in implant-based reconstruction with acellular dermal matrices, Ali A. Qureshi, Kristin Broderick, Susan Funk, Nancy Reaven, Marissa M. Tenenbaum, and Terence M. Myckatyn

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Measurement resources for dissemination and implementation research in health, Borsika A. Rabin, Cara C. Lewis, Wynne E. Norton, Gila Neta, David Chambers, Jonathan N. Tobin, Ross C. Brownson, and Russell E. Glasgow

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RNA microarray analysis of macroscopically normal articular cartilage from knees undergoing partial medial meniscectomy: Potential prediction of the risk for developing osteoarthritis, Muhammad Farooq Rai, Linda J. Sandell, Bo Zhang, Rick W. Wright, and Robert H. Brophy

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Diagnostics and training of affordance perception in healthy young adults - Implications for post-stroke neurorehabilitation, Jennifer Randerath and Scott H. Frey

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Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability, Gwendalyn J. Randolph and et al

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Genome-wide association studies in East Asians identify new loci for waist-hip ratio and waist circumference, Dabeeru Rao and et al

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Programmatic use of molecular xenomonitoring at the level of evaluation units to assess persistence of lymphatic filariasis in Sri Lanka, Ramakrishna U. Rao, Sandhya D. Samarasekera, Kumara C. Nagodavithana, Manjula W. Punchihewa, Tharanga D. M. Dassanayaka, Gamini P. K. D, Ethan Ford, Udaya S. B. Ranasinghe, Ralph H. Henderson, and Gary J. Weil

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A framework for interpreting type I error rates from a product-term model of interaction applied to quantitative traits, Tara J. Rao and Michael A. Province

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Lamin B1 and lamin B2 are long-lived proteins with distinct functions in retinal development, David Razafsky, Candace Ward, Chloe Potter, Wanqiu Zhu, Yunlu Xue, Vladimir J. Kefalov, Loren G. Fong, Stephen G. Young, and Didier Hodzic

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Clec16a is critical for autolysosome function and Purkinje cell survival, Veronika Redmann, Robert C. Orchard, Ashley Milam, Sunmin Park, Christine C. Yokoyama, Amal Kambal, Darren Kreamalmeyer, Karen Green, Paul M. Allen, Robert E. Schmidt, Herbert W. Virgin, Marie K. Bosch, Maolei Xiao, David M. Ornitz, Aaron DiAntonio, Shondra M. Pruett-Miller, Sungsu Kim, Wanda L. Beatty, and et al

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Computational neurorehabilitation: Modeling plasticity and learning to predict recovery, David J. Reinkensmeyer, Etienne Burdet, Maura Casadio, John W. Krakauer, Gert Kwakkel, Catherine E. Lang, Stephan P. Swinnen, Nick S. Ward, and Nicolas Schweighofer

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Heparan sulfate proteoglycans mediate Aβ-induced oxidative stress and hypercontractility in cultured vascular smooth muscle cells, Matthew R. Reynolds, Itender Singh, Tej D. Azad, Brandon B. Holmes, Phillip B. Verghese, Hans H. Dietrich, Marc Diamond, Guojun Bu, Byung Hee Han, and Gregory J. Zipfel

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ARTD1 regulates osteoclastogenesis and bone homeostasis by dampening NF-κB-dependent transcription of IL-1β, Agnieszka Robaszkiewicz, Chao Qu, Ewelina Wisnik, Tomasz Ploszaj, Ali Mirsaidi, Friedrich A. Kunze, Peter J. Richards, Paolo Cinelli, Gabriel Mbalaviele, and Michael O. Hottiger

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Implementation of a screening program for patients at risk for posttraumatic stress disorder, Carmen R. Roberts, Joanie E. Wofford, Haley M. Hoy, and Mitchell N. Faddis

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Synthetic ligands of cannabinoid receptors affect dauer formation in the nematode Caenorhabditis elegans, Pedro Reis Rodrigues, Tiffany K. Kaul, Jo-Hao Ho, Mark Lucanic, Kristopher Burkewitz, William B. Mair, Jason M. Held, Laura M. Bohn, and Matthew S. Gill

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ISG15 deficiency and increased viral resistance in humans but not mice, Marisela R. Rodriguez, Deborah J. Lenschow, and et al

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Stroke severity Is a crucial predictor of outcome: An international prospective validation study, Natalia S. Rost, Alex Bottle, Jin-Moo Lee, Marc Randall, Steven Middleton, Louise Shaw, Vincent Thijs, Gabriel J.E. Rinkel, Thomas M. Hemmen, and Global Comparators Stroke GOAL collaborators

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Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis, Megan K. Ruhland, Andrew J. Loza, Aude-Helene Capietto, Xianmin Luo, Brett L. Knolhoff, Kevin C. Flanagan, Brian A. Belt, Elise Alspach, Kathleen Leahy, Jingqin Luo, Andras Schaffer, John R. Edwards, Gregory Longmore, Roberta Faccio, David G. DeNardo, and Sheila A. Stewart

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Whole genome sequencing for genomics-guided investigations of Escherichia coli O157:H7 outbreaks, Brigida Rusconi, Fatemeh Sanjar, Sara S.K. Koenig, Mark K. Mammel, Phillip I. Tarr, and Mark Eppinger

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Targeted detection of genetic alterations reveal the prognostic impact of H3K27M and MAPK pathway aberrations in paediatric thalamic glioma, Scott Ryall, Rahul Krishnatry, Anthony Arnoldo, Pawel Buczkowicz, Matthew Mistry, Robert Siddaway, Cino Ling, Sanja Pajovic, Man Yu, Joshua B. Rubin, Juliette Hukin, Paul Steinbok, Ute Bartels, Eric Bouffet, Uri Tabori, and Cynthia Hawkins

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Maternal metabolic syndrome programs mitochondrial dysfunction via germline changes across three generations, Jessica L. Saben, Anna L. Boudoures, Zeenat Asghar, Alysha Thompson, Andrea Drury, Wendy Zhang, Maggie Chi, Andrew Cusumano, Suzanne Scheaffer, and Kelle H. Moley

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The Na+/Ca2+, K+ exchanger 2 modulates mammalian cone phototransduction, Keisuke Sakurai, Frans Vinberg, Tian Wang, Jeannie Chen, and Vladimir J. Kefalov

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Epidemiology of bloodstream infections in a multicenter retrospective cohort of liver transplant recipients, Carlos A.Q. Santos, Richard S. Hotchkiss, William C. Chapman, and Margaret A. Olsen

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The dimeric architecture of checkpoint Mec1ATR and Tel1ATM reveal a common structural organization, Marta Sawicka, Paulina H. Wanrooij, Vidya C. Darbari, Elias Tannous, Sarem Hailemariam, Daniel Bose, Alena V. Makarova, Peter M. Burgers, and Xiaodong Zhang

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Disruption of the Cdc42/Par6/aPKC or Dlg/ Scrib/Lgl polarity complex promotes epithelial proliferation via overlapping mechanisms, Gregory V. Schimizzi, Meghan T. Maher, Andrew J. Loza, and Gregory D. Longmore

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AXL receptor tyrosine kinase is required for T cell priming and antiviral immunity, Edward T. Schmid, Iris K. Pang, Eugenio A. Carrera Silva, Lidia Bosurgi, Jonathan J. Miner, Michael S. Diamond, Akiko Iwasaki, and Carla V. Rothlin

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Child stunting is associated with low circulating essential amino acids, Richard D. Semba, Michelle Shardell, Fayrouz A. Sakr Ashour, Ruin Moaddel, Indi Trehan, Kenneth M. Maleta, M. Isabel Ordiz, Klaus Kraemer, Mohammed A. Khadeer, Luigi Ferrucci, and Mark J. Manary

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Metabolic alterations in children with environmental enteric dysfunction, Richard D. Semba, Michelle Shardell, Indi Trehan, Ruin Moaddel, Kenneth M. Maleta, M. Isabel Ordiz, Klaus Kraemer, Mohammed Khadeer, Luigi Ferrucci, and Mark J. Manary

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Mice with genetic deletion of group VIA phospholipase A2β exhibit impaired macrophage function and increased parasite load in Trypanosoma cruzi-induced myocarditis, Janhavi Sharma, Jennifer R. Blase, Daniel F. Hoft, John O. Marentette, John Turk, and Jane McHowata

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Cardiac arrest-induced global brain hypoxia-ischemia during development affects spontaneous activity organization in rat sensory and motor thalamocortical circuits during adulthood, Michael Shoykhet and Jason W. Middleton

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The human experience with intravenous levodopa, Shan H. Siddiqi, Natalia K. Abraham, Christopher L. Geiger, Morvarid Karimi, Joel S. Perlmutter, and Kevin J. Black

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Tubular overexpression of Angiopoietin-1 attenuates renal fibrosis, Sudhir Singh, Scott R. Manson, Heedoo Lee, Yeawon Kim, Tuoen Liu, Qiusha Guo, Julio J. Geminiani, Paul F. Austin, and Ying Maggie Chen

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Cetuximab plus platinum-based chemotherapy in head and neck squamous cell carcinoma: A randomized, double-blind safety study comparing cetuximab produced from two manufacturing processes using the EXTREME study regimen, Denis Soulieres, Jose Luis Aguilar, Eric Chen, Krzysztof Misiukiewicz, Scott Ernst, Hyun Jung Lee, Katherine Bryant, Shuang He, Coleman K. Obasaju, Shao-Chun Chang, Steve Chin, and Douglas Adkins

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Adhesive pili in UTI pathogenesis and drug development, Caitlin N. Spaulding and Scott J. Hultgren

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T cells from patients with Candida sepsis display a suppressive immunophenotype, Andrej Spec, Yuichiro Shindo, Carey-Ann D. Burnham, Strother Wilson, Enyo A. Ablordeppey, Evan R. Beiter, Katherine Chang, Anne M. Drewry, and Richard S. Hotchkiss

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Negative emotional reactivity as a marker of vulnerability in the development of borderline personality disorder symptoms, Stephanie D. Stepp, Lori N. Scott, Neil P. Jones, Diana J. Whalen, and Alison E. Hipwell

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Emerging executive functioning and motor development in infants at high and low risk for autism spectrum disorder, Tanya St. John, Annette M. Estes, Stephen R. Dager, Penelope Kostopoulos, Jason J. Wolff, Juhi Pandey, Jed T. Elison, Sarah J. Paterson, Robert T. Schultz, Kelly Botteron, Heather Hazlett, and Joseph Piven

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Proficient replication of the yeast genome by a viral DNA polymerase, Joseph L. Stodola, Carrie M. Stith, and Peter M. Burgers

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Oxidative DNA damage stalls the human mitochondrial replisome, Gorazd Stojkovič, Alena V. Makarova, Paulina H. Wanrooij, Josefin Forslund, Peter M. Burgers, and Sjoerd Wanrooij

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NAMPT-mediated NAD+ biosynthesis in adipocytes regulates adipose tissue function and multi-organ insulin sensitivity in mice, Kelly L. Stromsdorfer, Shintaro Yamaguchi, Myeong Jin Yoon, Anna C. Moseley, Michael P. Franczyk, Shannon C. Kelly, Nathan Qi, Shin-ichiro Imai, and Jun Yoshino

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A randomized controlled trial of directive and nondirective smoking cessation coaching through an employee quitline, Walton Sumner II, Mark S. Walker, Gabrielle R. Hightstein, Irene Fischer, Yan Yan, Amy McQueen, and Edwin B. Fisher

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Mesothelin's minimal MUC16 binding moiety converts TR3 into a potent cancer therapeutic via hierarchical binding events at the plasma membrane, Yang Su, Katharina Tatzel, Xuejun Wang, Brian Belt, Pratibha Binder, Lindsay Kuroki, Matthew A. Powell, David G. Mutch, William G. Hawkins, and Dirk Spitzer

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Quantitative amyloid imaging in autosomal dominant Alzheimer’s disease: Results from the DIAN study group, Yi Su, Tyler M. Blazey, Christopher J. Owen, Jon J. Christensen, Karl Friedrichsen, Nelly Joseph-Mathurin, Qing Wang, Russ C. Hornbeck, Beau M. Ances, Abraham Z. Snyder, Lisa A. Cash, Eric McDade, Chengjie Xiong, Daniel S. Marcus, John C. Morris, Randall J. Bateman, Tammie L. S. Benzinger, and et al.

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Myeloid deletion of nemo causes osteopetrosis in mice owing to upregulation of transcriptional repressors, Gaurav Swarnkar, Kyuhwan Shim, Amjad M. Nasir, Kuljeet Seehra, Hung-Po (Tim) Chen, Gabriel Mbalaviele, and Yousef Abu-Amer

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Comparison of open gastrostomy tube to percutaneous endoscopic gastrostomy tube in lung transplant patients, Sharven Taghavi, Vishnu Ambur, Senthil Jayarajan, John Gaughan, Yoshiya Toyoda, Elizabeth Dauer, Lars Ola Sjoholm, Abhijit Pathak, Thomas Santora, and Amy J. Goldberg

Membrane-proximal TRAIL species are incapable of inducing short circuit apoptosis signaling: implications for drug development and basic cytokine biology, Katharina Tatzel, Lindsay Kuroki, Igor Dmitriev, Elena Kashentseva, David T. Curiel, S. Peter Goedegebuure, Matthew A. Powell, David G. Mutch, William G. Hawkins, and Dirk Spitzer

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Postoperative severe headache following cervical posterior surgical fixation from C2 distally, Ryoji Tauchi, Sang-Hun Lee, Jin-Young Kim, Yong-Chan Kim, Colleen Peters, Shiro Imagama, Naoki Ishiguro, Jacob Buchowski, and K. Daniel Riew

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A genome-wide study of blood pressure in African Americans accounting for gene-smoking interaction, Jacquelyn Y. Taylor, Karen Schwander, Sharon L. R. Kardia, Donna Arnett, Jingjing Liang, Steven C. Hunt, D C. Rao, and Yan V. Sun

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Role of metal-dependent regulation of ESX-3 secretion in intracellular survival of Mycobacterium tuberculosis, Emir Tinaztepe, Jun-Rong Wei, Jenelle Raynowska, Cynthia Portal-Celhay, Victor Thompson, and Jennifer A. Philips

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The Z-cad dual fluorescent sensor detects dynamic changes between the epithelial and mesenchymal cellular states, M. J. Toneff, A. Sreekumar, A. Tinnirello, P. Den Hollander, S. Habib, Shunqiang Li, M. J. Ellis, L. Xin, S. A. Mani, and J. M. Rosen

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Activation of proteinase 3 contributes to Non-alcoholic Fatty Liver Disease (NAFLD) and insulin resistance, Erik JM Toonen, Andreea-Manuela Mirea, Cees J. Tack, Rinke Stienstra, Dov B. Ballak, Janna A. van Diepen, Anneke Hijmans, Triantafyllos Chavakis, Wim H. Dokter, Christine TN Pham, Mihai G. Netea, Charles A. Dinarello, and Leo AB Joosten

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A disintegrin and metalloproteinase10 (ADAM10) regulates NOTCH signaling during early retinal development, Joseph A. Toonen, Adam Ronchetti, and D. J. Sidjanin

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Prevalence of asymptomatic bacteriuria in hospitalized patients, Sergio E. Trevino, Jeffrey P. Henderson, Jiami Wu, Candice Cass, and Jonas Marschall

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The impact of nighttime intensivists on medical intensive care unit infection-related indicators, Abhaya Trivedi, Kathleen M. McMullen, Hilary M. Babcock, and Marin H. Kollef

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Coronary CT angiography versus standard emergency department evaluation for acute chest pain and diabetic patients: Is there benefit with early coronary CT angiography? Results of the randomized comparative effectiveness ROMICAT II trial, Quynh A. Truong, Joshua Schulman-Marcus, Pearl Zakroysky, Eric T. Chou, John T. Nagurney, Jerome L. Fleg, David A. Schoenfeld, James E. Udelson, Udo Hoffmann, and Pamela K. Woodard

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A randomized trial comparing skin antiseptic agents at Cesarean delivery, Methodius G. Tuuli, Jingxia Liu, Molly J. Stout, Shannon Martin, Alison G. Cahill, Anthony O. Odibo, Graham A. Colditz, and George A. Macones

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Butyrate and bioactive proteolytic form of Wnt-5a regulate colonic epithelial proliferation and spatial development, Kazuhiko Uchiyama, Toshio Sakiyama, Takumu Hasebe, Mark W. Musch, Hiroyuki Miyoshi, Yasushi Nakagawa, Tong-Chuan He, Lev Lichtenstein, Yuji Naito, Yoshito Itoh, Toshikazu Yoshikawa, Bana Jabri, Thaddeus Stappenbeck, and Eugene B. Chang

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Induction of protective immunity to Cryptococcal infection in mice by a heat-killed, chitosan-deficient strain of Cryptococcus neoformans, Rajendra Upadhya, Woei C. Lam, Brian Maybruck, Charles A. Specht, Stuart M. Levitz, and Jennifer K. Lodge

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Wolfram syndrome: Diagnosis, management, and treatment, Fumihiko Urano

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Community rates of IgG4 antibodies to Ascaris haemoglobin reflect changes in community egg loads following mass drug administration, Johnny Vlaminck, Taniawati Supali, Peter Geldhof, Cornelis H. Hokke, Peter U. Fischer, and Gary J. Weil

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Mapping rare, deleterious mutations in Factor H: Association with early onset, drusen burden, and lower antigenic levels in familial AMD, Erin K. Wagner, Soumya Raychaudhuri, Mercedes B. Villalonga, Anuja Java, Michael P. Triebwasser, Mark J. Daly, John P. Atkinson, and Johanna M. Seddon

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Is a fully wrapped SSB-DNA complex essential for Escherichia coli survival?, Vincent M. Waldman, Elizabeth Weiland, Alexander G. Kozlov, and Timothy M. Lohman

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Marrow adipose tissue expansion coincides with insulin resistance in MAGP1-deficient mice, Tezin A. Walji, Sarah E. Turecamo, Alejandro Coca Sanchez, Bryan A. Anthony, Grazia Abou-Ezzi, Erica L. Scheller, Daniel C. Link, Robert P. Mecham, and Clarissa S. Craft

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Elevated p62/SQSTM1 determines the fate of autophagy-deficient neural stem cells by increasing superoxide, Chenran Wang, Song Chen, Syn Yeo, Gizem Karsli-Uzunbas, Eileen White, Noboru Mizushima, Herbert W. Virgin, and Jun-Lin Guan

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Poly-ADP-ribosylation-mediated degradation of ARTD1 by the NLRP3 inflammasome is a prerequisite for osteoclast maturation, C Wang, C Qu, Y Alippe, S L. Bonar, R Civitelli, Y Abu-Amer, M O. Hottiger, and G Mbalaviele