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Submissions from 2016

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Regulation of monocyte cell fate by blood vessels mediated by Notch signalling, Carlos G. Briseño, Kenneth M. Murphy, and et al

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Nonalcoholic fatty liver disease: Pros and cons of histologic systems of evaluation, Elizabeth M. Brunt

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Lipedema: A relatively common disease with extremely common misconceptions, Donald W. Buck II and Karen L. Herbst

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Accuracy of coverage survey recall following an integrated mass drug administration for lymphatic filariasis, schistosomiasis, and soil-transmitted helminthiasis, Philip J. Budge, Edmond Sognikin, Amanda Akosa, Els M. Mathieu, and Michael Deming

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Topical decolonization does not eradicate the skin microbiota of community-dwelling or hospitalized adults, Carey-Ann D. Burnham, Patrick G. Hogan, Meghan A. Wallace, Elena Deych, William Shannon, David K. Warren, and Stephanie A. Fritz

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Impact of time to appropriate therapy on mortality in patients with vancomycin-intermediate Staphylococcus aureus infection, Jason P. Burnham, Carey-Ann D. Burnham, David K. Warren, and Marin H. Kollef

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Deregulated lipid sensing by intestinal CD36 in diet-induced hyperinsulinemic obese mouse model, Marjorie Buttet, Helene Poirier, Veronique Traynard, Kevin Gaire, Thi Thu Trang Tran, Sinju Sundaresan, Philippe Besnard, Nada A. Abumrad, and Isabelle Niot

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Neuromodulation of the failing heart: Lost in translation?, Mirnela Byku and Douglas L. Mann

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Hypoglycemia during moderate intensity exercise reduces counterregulatory responses to subsequent hypoglycemia, W. Todd Cade, Nadia Khoury, Suzanne Nelson, Angela Shackleford, Katherine Semenkovich, Melissa J. Krauss, and Ana Maria Arbelaez

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Genome-wide analysis of genetic correlation in dementia with Lewy bodies, Parkinson's and Alzheimer's diseases, Nigel J. Cairns and et al

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The first NINDS/NIBIB consensus meeting to define neuropathological criteria for the diagnosis of chronic traumatic encephalopathy, Nigel J. Cairns and et al

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The effect of dopaminergic medication on beat-based auditory timing in Parkinson’s disease, Daniel J. Cameron, Kristen A. Pickett, Gammon M. Earhart, and Jessica A. Grahn

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ATG16L1 governs placental infection risk and preterm birth in mice and women, Bin Cao, Colin Macones, and Indira U. Mysorekar

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MiR-15a/16 regulates apoptosis of lung epithelial cells after oxidative stress, Yong Cao, Duo Zhang, Hyung-Geun Moon, Heedoo Lee, Jeffrey A. Haspel, Kebin Hu, Lixin Xie, and Yang Jin

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Interleukin-17A contributes to the control of Streptococcus pyogenes colonization and inflammation of the female genital tract, Alison J. Carey, Jason B. Weinberg, Suzanne R. Dawid, Carola Venturini, Alfred K. Lam, Victor Nizet, Michael G. Caparon, Mark J. Walker, and Michael E. Watson

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Associations between polygenic risk for psychiatric disorders and substance involvement, Caitlin E. Carey, Arpana Agrawal, Kathleen K. Bucholz, Sarah M. Hartz, MIchael T. Lynskey, Elliot C. Nelson, Laura J. Bierut, and Ryan Bogdan

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Controlling nosocomial transmission of drug-resistant pathogens at different endemic stages in a resource-limited setting, Abigail L. Carlson, Nattapol Pruetpongpun, Aubonphan Buppajarntham, and Anucha Apisarnthanarak

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Association of functional impairments and co-morbid conditions with driving performance among cognitively normal older adults, David B. Carr, Peggy P. Barco, Ganesh M. Babulal, Sarah H. Stout, Anne M. Johnson, Chengjie Xiong, John C. Morris, and Catherine M. Roe

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Encouraging antibiotic development and endorsing conservation: Tandem approaches to our declining antibiotic reserves, Kevin A. Cassady, Jason G. Newland, and Lisa Saiman

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Impact of age and sex on outcomes and hospital cost of acute asthma in the United States, 2011-2012, Mario Castro and et al.

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Longitudinal evaluation of cognitive functioning in young children with type 1 diabetes over 18 months, M. Allison Cato, Nelly Mauras, Paul Mazaika, Craig Kollman, Peiyao Cheng, Tandy Aye, Jodie Ambrosino, Roy W. Beck, Katrina J. Ruedy, Allan L. Reiss, Michael Tansey, Neil H. White, and Tamara Hershey

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Striatal activity is associated with deficits of cognitive control and aberrant salience for patients with schizophrenia, Alan E. Ceaser and Deanna M. Barch

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The NADase-negative variant of the Streptococcus pyogenes toxin NAD+ glycohydrolase induces JNK1-mediated programmed cellular necrosis, Sukantha Chandrasekaran and Michael G. Caparon

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A critical review of perfluorooctanoate and perfluorooctanesulfonate exposure and immunological health conditions in humans, Ellen T. Chang, Hans-Olov Adami, Paolo Boffetta, H. James Wedner, and Jack S. Mandel

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Derivation of two critical appraisal scores for trainees to evaluate online educational resources: A METRIQ study, Teresa M. Chan, Brent Thoma, Keeth Krishnan, Michelle Lin, Christopher R. Carpenter, Matt Astin, and Kulamakan Kulasegaram

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Advances in cholangiocarcinoma research: Report from the third Cholangiocarcinoma Foundation Annual Conference, William Chapman and et al

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Long-term effects of robotic hippotherapy on dynamic postural stability in cerebral palsy, Young Joo Cha, Megan Stanley, Tim Shurtleff, and Joshua S.H. You

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Genetic risk can be decreased: Quitting smoking decreases and delays lung cancer for smokers with high and low CHRNA5 risk genotypes — A meta-analysis, Li-Shiun Chen, Amy Horton, Robert Culverhouse, Sarah Hartz, Nancy Saccone, Laura J. Bierut, and et al

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Automated quantification of cerebral edema following hemispheric infarction: Application of a machine-learning algorithm to evaluate CSF shifts on serial head CTs, Yasheng Chen, Rajat Dhar, Laura Heitsch, Andria Ford, Israel Fernandez-Cadenas, Caty Carrera, Joan Montaner, Weili Lin, Dinggang Shen, Hongyu An, and Jin-Moo Lee

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Measurement of circulating filarial antigen levels in human blood with a point-of-care test strip and a portable spectrodensitometer, Cédric B. Chesnais, Johnny Vlaminck, Billy Kunyu-Shako, Sébastien D. Pion, Naomi-Pitchouna Awaca-Uvon, Gary J. Weil, Dieudonné Mumba, and Michel Boussinesq

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A diet mimicking fasting promotes regeneration and reduces autoimmunity and multiple sclerosis symptoms, In Young Choi, Laura Piccio, Patra Childress, Bryan Bollman, Arko Ghosh, Sebastian Brandhorst, Jorge Suarez, Andreas Michalsen, Anne H. Cross, Todd E. Morgan, Min Wei, Friedemann Paul, Markus Bock, and Valter D. Longo

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Genome-wide polygenic scores for age at onset of alcohol dependence and association with alcohol-related measures, Y-L Chou, P A F. Madden, L J. Bierut, A C. Heath, K K. Bucholz, and A Agrawal

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Hormonal responses to cholinergic input are different in humans with and without type 2 diabetes mellitus, Sara Chowdhury, Songyan Wang, Jundit Dunai, Rachel Kilpatrick, Lauren Z. Oestricker, Michael J. Wallendorf, Bruce W. Patterson, Dominic N. Reeds, and Burton M. Wice

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Rectal budesonide and mesalamine formulations in active ulcerative proctosigmoiditis: efficacy, tolerance, and treatment approach, George P. Christophi, Arvind Rengarajan, and Matthew A. Ciorba

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The effect of chloroquine on immune activation and interferon signatures associated with HIV-1, David Clifford and et al

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Nurses' Health Study: Demonstrating the impact of research, and adapting new measures and approaches to increase relevance and effect of cohort studies, Graham A. Colditz

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Baseline results of the NeuroNEXT spinal muscular atrophy infant biomarker study, Anne M. Connolly and et al

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Breast reconstruction after mastectomy at a comprehensive cancer center, Shahnjayla K. Connors, Melody S. Goodman, Terence Myckatyn, Julie Margenthaler, and Sarah Gehlert

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Metabolic requirements of Escherichia coli in intracellular bacterial communities during urinary tract infection pathogenesis, Matt S. Conover, Maria Hadjifrangiskou, Joseph J. Palermo, Michael E. Hibbing, Karen W. Dodson, and Scott J. Hultgren

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Child maltreatment prevention and the scope of child and adolescent psychiatry, John Constantino

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The action of discoidin domain receptor 2 in basal tumor cells and stromal cancer-associated fibroblasts Is critical for breast cancer metastasis, Callie A.S. Corsa, Audrey Brenot, Whitney R. Grither, Samantha Van Hove Washington University School of Medicine in St. Louis, Andrew J. Loza, Kun Zhang, Suzanne M. Ponik, Yuming Liu, David G. DeNardo, Kevin W. Eliceiri, Patricia J. Keely, and Gregory D. Longmore

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Urb-RIP - An adaptable and efficient approach for immunoprecipitation of RNAs and associated RNAs/proteins, Kyle A. Cottrell and Sergej Djuranovic

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Trajectories of depressive symptoms after hip fracture, P. Cristancho, E. J. Lenze, M. S. Avidan, and K. S. Rawson

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Dynorphin controls the gain of an amygdalar anxiety circuit, NIcole A. Crowley, Daniel W. Bloodgood, J. Andrew Hardaway, Alexis M. Kendra, Jordan G. McCall, Ream Al-Hasani, Nora M. McCall, Waylin Yu, Zachary L. Schools, Michael J. Krashes, Bradford B. Lowell, Jennifer L. Whistler, Michael R. Bruchas, and Thomas L. Kash

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Influence of coding variability in APP-Aβ metabolism genes in sporadic Alzheimer’s disease, Carlos Cruchaga and et al.

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Drug development in Alzheimer’s disease: The path to 2025, Jeffrey Cummings, Paul S. Aisen, Bruno DuBois, Lutz Frölich, Clifford R. Jack Jr., Roy W. Jones, John C. Morris, Joel Raskin, Sherie A. Dowsett, and Philip Scheltens

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Innovative solutions to sticky situations: Antiadhesive strategies for treating bacterial infections, Zachary T. Cusumano, Roger D. Klein, and Scott J. Hultgren

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Postoffer Pre-Placement Screening for Carpal Tunnel Syndrome in Newly Hired Manufacturing Workers, Ann Marie Dale, Bethany T. Gardner, Skye Buckner-Petty, Jaime R. Strickland, and Bradley Evanoff

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Evaluation of a Participatory Ergonomics Intervention in Small Commercial Construction Firms, Ann Marie Dale, Lisa Jaegers, Laura Welch, Bethany T. Gardner, Bryan Buchholz, Nancy Weaver, and Bradley A. Evanoff

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Complexities of X chromosome inactivation status in female human induced pluripotent stem cells—a brief review and scientific update for autism research, Mary G. Dandulakis, Kesavan Meganathan, Kristen L. Kroll, Azad Bonni, and John N. Constantino

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Changes in the relative abundance of two Saccharomyces species from oak forests to wine fermentations, Sofia Dashko, Ping Liu, Helena Volk, Lorena Butinar, Jure Piškur, and Justin C. Fay

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A case study in the history of neurology, Gregory S. Day, David F. Tang-Wai, and Michel C.F. Shamy

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The two sides of sensory–cognitive interactions: Effects of age, hearing acuity, and working memory span on sentence comprehension, Renee DeCaro, Jonathan E. Peelle, Murray Grossman, and Arthur Wingfield

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Genome sequences of nine gram-negative vaginal bacterial isolates, Grace E. Deitzler, Maria J. Ruiz, Wendy Lu, Cory Weimer, SoEun Park, Lloyd S. Robinson, Kymberlie Hallsworth-Pepin, Aye Wollam, Makedonka Mitreva, Warren G. Lewis, and Amanda L. Lewis

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Genome sequences of 14 Firmicutes strains isolated from the human vagina, Grace E. Deitzler, Maria J. Ruiz, Cory Weimer, SoEun Park, Lloyd Robinson, Kymberlie Hallsworth-Pepin, Aye Wollam, Makedonka Mitreva, Amanda L. Lewis, and Warren G. Lewis

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Thymic stromal lymphopoietin blocks early stages of breast carcinogenesis, Shadmehr Demehri, Trevor J. Cunningham, Sindhu Manivasagam, Kenneth H. Ngo, Sara Moradi Tuchayi, Rasikia Reddy, Melissa A. Meyers, David G. DeNardo, and Wayne M. Yokoyama

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Chitinase-3-like 1 protein (CHI3L1) locus influences cerebrospinal fluid levels of YKL-40, Yuetiva Deming, Kathleen Black, David Carrell, Yefei Cai, Jorge L. Del-Aguila, Maria Victoria Fernandez, John Budde, ShengMei Ma, Benjamin Saef, Bill Howells, Sarah Bertelsen, Kuan-lin Huang, Courtney L. Sutphen, Rawan Tarawneh, Anne M. Fagan, David M. Holtzman, John C. Morris, Alison M. Goate, Joseph D. Dougherty, and Carlos Cruchaga

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Nicotinamide mononucleotide supplementation reverses vascular dysfunction and oxidative stress with aging in mice, Natalie E. de Picciotto, Lindsey B. Gano, Lawrence C. Johnson, Christopher R. Martens, Amy L. Sindler, Kathryn F. Mills, Shin-ichiro Imai, and Douglas R. Seals

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Epidemiological and economic burden of Clostridium difficile in the United States: Estimates from a modeling approach, Kamal Desai, Swati B. Gupta, Erik R. Dubberke, Vimalanand S. Prabhu, Chantelle Browne, and T. Christopher Mast

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Progressive elbow pain, Alexis Descatha, Thomas Despreaux, Ryan P. Calfee, Bradley Evanoff, and Olivier Saint-Lary

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From alcohol initiation to tolerance to problems: Discordant twin modeling of a developmental process, Arielle R. Deutsch, Wendy S. Slutske, Michael T. Lynskey, Kathleen K. Bucholz, Pamela A. F. Madden, and Nicholas G. Martin

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Sexual dimorphism in myocardial acylcarnitine and triglyceride metabolism, Sriram Devanathan, Timothy D. Whitehead, Nicole Fettig, Robert J. Gropler, Samuel Nemanich, and Kooresh I. Shoghi

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Academic cross-pollination: The role of disciplinary affiliation in research collaboration, Amar Dhand, Douglas A. Luke, Bobbi J. Carothers, and Bradley A. Evanoff

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Technical note: Recommendations for a standard procedure to assess cortical bone at the tissue-level in vivo using impact microindentation, A. Diez-Perez, M. L. Bouxsein, E. F. Eriksen, S. Khosla, J. S. Nyman, S. Papapoulos, and S. Y. Tang

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Consumption of caffeinated products and cardiac ectopy, Shalini Dixit, Phyllis K. Stein, Thomas A. Dewland, Jonathan W. Dukes, Eric Vittinghoff, Susan R. Heckbert, and Gregory M. Marcus

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Chemical chaperone TUDCA prevents apoptosis and improves survival during polymicrobial sepsis in mice, Marcel Doerflinger, Jason Glab, Christina Nedeva, Irvin Jose, Ann Lin, Lorraine O’Reilly, Cody Allison, Marc Pellegrini, Richard S. Hotchkiss, and Hamsa Puthalakath

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Investigation of linezolid resistance in staphylococci and enterococci, Christopher D. Doern, Jason Y. Park, Michael Gallegos, Debbie Alspaugh, and Carey-Ann D. Burnham

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Change in angina symptom status after acute myocardial infarction and its association with readmission risk: An analysis of the Translational Research Investigating Underlying Disparities in Acute Myocardial Infarction Patients' Health Status (TRIUMPH) registry, Jacob A. Doll, Fengming Tang, Sharon Cresci, P. Michael Ho, Thomas M. Maddox, John A. Spertus, and Tracy Y. Wang

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Practical considerations for noise power spectra estimation for clinical CT scanners, Steven Dolly, Hsin-Chen Chen, Mark Anastasio, Sasa Mutic, and Hua Li

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Cytokines and chemokines in Mycobacterium tuberculosis infection, Racquel Domingo-Gonzalez, Oliver Prince, Andrea Cooper, and Shabaana A. Khader

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Broadly neutralizing activity of Zika virus-immune sera identifies a single viral serotype, Kimberly A. Dowd, Christina R. DeMaso, Rebecca S. Pelc, Scott D. Speer, Alexander R.Y. Smith, Leslie Goo, Derek J. Platt, John R. Mascola, Barney S. Graham, Mark J. Mulligan, Michael S. Diamond, Julie E. Ledgerwood, and Theodore C. Pierson

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Secondary consent to biospecimen use in a prostate cancer biorepository, Bettina F. Drake, Katherine Brown, Lucy D'Agostino McGowan, Jennifer Haslag-Minoff, and Kimberly Kaphingst

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Comparison of monocyte human leukocyte antigen-DR expression and stimulated tumor necrosis factor alpha production as outcome predictors in severe sepsis: A prospective observational study, Anne M. Drewry, Enyo A. Ablordeppey, Ellen T. Murray, Evan R. Beiter, Andrew H. Walton, Mark W. Hall, and Richard S. Hotchkiss

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Identification of Medicare recipients at highest risk for Clostridium difficile infection in the US by population attributable risk analysis, Erik R. Dubberke, Margaret A. Olsen, Dustin Stwalley, Ciaran P. Kelly, Dale N. Gerding, Yinong Young-Xu, and Cedric Mahe

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Professional Decision-Making in Research (PDR): The validity of a new measure, James M. DuBois, John T. Chibnall, Raymond C. Tait, Jillon S. Vander Wal, Kari A. Baldwin, Alison L. Antes, and Michael D. Mumford

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Quantifying transmission of clostridium difficile within and outside healthcare settings, David P. Durham, Margaret A. Olsen, Erik R. Dubberke, Alison P. Galvani, and Jeffrey P. Townsend

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The basal bodies of Chlamydomonas reinhardtii, Susan Dutcher and Eileen T. O'Toole

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Muddled mechanisms: recent progress towards antimalarial target identification [version 1; referees: 2 approved], Rachel L. Edwards and Audrey R. Odom John

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Illustrating and homology modeling the proteins of the Zika virus [version 2; referees: 2 approved], Sean Ekins, John Liebler, Bruno J. Neves, Warren G. Lewis, Megan Coffee, Rachelle Bienstock, Christopher Southan, and Carolina H. Andrade

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Identifying the dominant personality profiles in medical students: Implications for their well-being and resilience, Diann S. Eley, Janni Leung, Barry A. Hong, Kevin M. Cloninger, and C. Robert Cloninger

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Genetic ablation of calcium-independent phospholipase A2γ induces glomerular injury in mice, Hanan Elimam, Joan Papillon, Daniel R. Kaufman, Julie Guillemette, Lamine Aoudjit, Richard W. Gross, Tomoko Takano, and Andrey V. Cybulsky

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Preventing germ cell death by inactivating aryl hydrocarbon receptor (AHR), P Esakky and K H. Moley

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Soluble amyloid-beta aggregates from human Alzheimer's disease brains, Thomas J. Esparza, Norelle C. Wildburger, Hao Jiang, Mihika Gangolli, Nigel J. Cairns, Randall J. Bateman, and David L. Brody

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Results of a Fall Prevention Educational Intervention for Residential Construction, Bradley Evanoff, Ann Marie Dale, Angelique Zeringue, Mark Fuchs, John Gaal, Hester J. Lipscomb, and Vicki Kaskutas

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Long-term Symptomatic, Functional, and Work Outcomes of Carpal Tunnel Syndrome among Construction Workers, Bradley Evanoff, Bethany T. Gardner, Jaime R. Strickland, Skye Buckner-Petty, Alfred Franzblau, and Ann Marie Dale

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Migratory CD103+ dendritic cells suppress helminth-driven type 2 immunity through constitutive expression of IL-12, Bart Evans, Roxane Tussiwand, Leentje Dreesen, Keke C. Fairfax, Stanley Ching-Cheng Huang, Amber M. Smith, Christina M. O'Neill, Wing Y. Lam, Brian T. Edelson, Joseph F. Urban Jr, and Kenneth M. Murphy

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A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape, Mary F. Feitosa, Ingrid B. Borecki, Dabeeru Rao, Treva K. Rice, Yun Ju Sung, and et al

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A comparative study of automatic image segmentation algorithms for target tracking in MR-IGRT, Yuan Feng, Iwan Kawrakow, Jeff Olsen, Parag J. Parikh, Camille Noel, Omar Wooten, Dongsu Du, Sasa Mutic, and Yanle Hu

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Accumulation of long-chain bases in yeast promotes their conversion to a long-chain base vinyl ether, Fernando Fernando Martínez-Montañés, Museer A. Lone, Fong-Fu Hsu, and Roger Schneiter

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Effect of cervical length recovery after laser surgery for twin-twin transfusion syndrome, Matthew Finneran, Lorene Temming, Megan Templin, and Courtney Stephenson

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Interactions between pluripotency factors specify cis-regulation in embryonic stem cells, Chris Fiore and Barak A. Cohen

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A recombinant positive control for serology diagnostic tests supporting elimination of Onchocerca volvulus, Peter U. Fischer and et al.

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Mycobacterium tuberculosis transcription machinery: Ready to respond to host attacks, Kelly Flentie, Ashley L. Garner, and Christina L. Stallings

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Comparing aging and fitness effects on brain anatomy, Mark A. Fletcher, Kathy A. Low, Rachel Boyd, Benjamin Zimmerman, Brian A. Gordon, Chin H. Tan, Nils Schneider-Garces, Bradley P. Sutton, Gabriele Gratton, and Monica Fabiani

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Antibody-based therapy for enterococcal catheter-associated urinary tract infections, Ana L. Flores-Mireles, Jennifer N. Walker, Aaron Potretzke, Henry L. Schreiber IV, Jerome S. Pinkner, Tyler M. Bauman, Alyssa M. Park, Alana Desai, Scott J. Hultgren, and Michael G. Caparon

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A Plasmodium promiscuous T cell epitope delivered within the Ad5 hexon protein enhances the protective efficacy of a protein based malaria vaccine, Jairo Andres Fonseca, Monica Cabrera-Mora, Elena A. Kashentseva, John Paul Villegas, Alejandra Fernandez, Amelia Van Pelt, Igor P. Dmitriev, David T. Curiel, and Alberto Moreno

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Decreased consumption of branched-chain amino acids improves metabolic health, Luigi Fontana, Edda Cava, Francesco Spelta, Valeria Tosti, Nicola Veronese, Beatrice Bertozzi, Terri Pietka, Arnold D. Bullock, Robert S. Figenshau, Gerald L. Andriole, and et al

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Effects of 2-year calorie restriction on circulating levels of IGF-1, IGF-binding proteins and cortisol in nonobese men and women: A randomized clinical trial, Luigi Fontana, Dennis T. Villareal, Sai K. Das, Steven R. Smith, Simin N. Meydani, Anastassios G. Pittas, Samuel Klein, Manjushri Bhapkar, James Rochon, Eric Ravussin, John O. Holloszy, and CALERIE Study Group

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Improved cardiovascular disease outcomes in older adults, Daniel E. Forman, Karen Alexander, Ralph G. Brindis, Anne B. Curtis, Matthew Maurer, Michael W. Rich, Laurence Sperling, and Nanette K. Wenger

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Identification of genes conferring tolerance to lignocellulose-derived inhibitors by functional selections in soil metagenomes, Kevin J. Forsberg, Sanket Patel, Evan Witt, Bin Wang, Tyler D. Ellison, and Gautam Dantas