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Submissions from 2015

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Construction and evaluation of novel rhesus monkey adenovirus vaccine vectors, Peter Abbink, Lori F. Maxfield, David Ng'ang'a, Erica N. Borducchi, M Justin Iampletro, Christine A. Bricault, Jeffrey E. Teigler, Stephen Blackmore, Lily Parenteau, Kshitij Wagh, Scott A. Handley, Guoyan Zhao, Herbert W. Virgin, Bette Korber, and Dan H. Barouch

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TBX6 null variants and a common hypomorphic allele in congenital scoliosis, H. Al-Kateb, S. Kulkarni, and et al

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In vivo creatine kinase reaction kinetics at rest and stress in type II diabetic rat heart, Adil Bashir, Andrew R. Coggan, and Robert J. Gropler

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Automatic analysis (aa): Efficient neuroimaging workflows and parallel processing using Matlab and XML, Rhodri Cusack, Alejandro Vicente-Grabovetsky, Daniel J. Mitchell, Conor J. Wild, Tibor Auer, Annika C. Linke, and Jonathan E. Peelle

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Trends in opioid analgesic abuse and mortality in the United States, Richard C. Dart, Hilary L. Surratt, Theodore J. Cicero, Mark W. Parrino, S Geoff Severtson, Becki Bucher-Bartelson, and Jody L. Green

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Peptidases compartmentalized to the Ascaris suum intestinal lumen and apical intestinal membrane, Douglas P. Jasmer, Bruce A. Rosa, and Makedonka Mitreva

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Pulmonary Function Following Adult Spinal Deformity Surgery: Minimum Two-Year Follow-up, Ronald A. Lehman Jr., Daniel G. Kang, Lawrence G. Lenke, Jeremy J. Stallbaumer, and Brenda A. Sides

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Influence of model boundary conditions on blood flow patterns in a patient specific stenotic right coronary artery, Biyue Liu, Jie Zheng, Richard Bach, and Dalin Tang

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Detailed phenotypic and molecular analyses of genetically modified mice generated by CRISPR-Cas9-mediated editing, Bijal A. Parikh, Diana L. Beckman, Swapneel J. Patel, J. Michael White, and Wayne M. Yokoyama

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Comparison of chromogenic media for recovery of carbapenemase-producing enterobacteriaceae (CPE) and evaluation of CPE prevalence at a tertiary care academic medical center, Morgan A. Pence, Tiffany Hink, and Carey-Ann D. Burnham

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A cost-effectiveness analysis of a chemoresponse assay for treatment of patients with recurrent epithelial ovarian cancer, Victoria Plamadeala, Joseph L. Kelley, John K. Chan, Thomas C. Krivak, Michael J. Gabrin, Stacey L. Brower, Matthew A. Powell, Thomas J. Rutherford, and Robert L. Coleman

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Identification of hematomas in mild traumatic brain injury using an index of quantitative brain electrical activity, Leslie S. Prichep, Rosanne Naunheim, Jeffrey Bazarian, W. Andrew Mould, and Daniel Hanley

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Seminoma presenting as renal mass, inferior vena caval thrombus, and regressed testicular mass, Valary T. Raup, Michael H. Johnson, Jonathan R. Weese, Ian S. Hagemann, Stephen D. Marshall, and Steven B. Brandes

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Are movement disorders and sensorimotor injuries pathologic synergies? When normal multi-joint movement synergies become pathologic, Marco Santello and Catherine E. Lang

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Protein kinase Cδ mediates histamine-evoked itch and responses in pruriceptors, Manouela V. Valtcheva, Steve Davidson, Chengshui Zhao, and Robert W. Gereau

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Personalization of cancer treatment using predictive simulation, Ravi Vij, Mark Fiala, Justin King, and et al

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ανβ3-targeted copper nanoparticles incorporating an Sn 2 lipase-labile fumagillin prodrug for photoacoustic neovascular imaging and treatment, Ruiying Zhang, Dipanjan Pan, Xin Cai, Xiaoxia Yang, Angana Senpan, John S. Allen, Gregory M. Lanza, and Lihong V. Wang

Submissions from 2014

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Current clinical practice: differential management of uveal melanoma in the era of molecular tumor analyses, Thomas M. Aaberg Jr., Robert W. Cook, Kristen Oelschlager, Derek Maetzold, P. Kumar Rao, and John O. Mason III

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Identification and characterization of alternative splicing in parasitic nematode transcriptomes, Sahar Abubucker, Samantha N. McNulty, Bruce A. Rosa, and Makedonka Mitreva

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Molecular epidemiology of carbapenem-nonsusceptible Acinetobacter baumannii in the United States, Jennifer M. Adams-Haduch, Ezenwa O. Onuoha, Tatiana Bogdanovich, Guo-Bao Tian, Jonas Marschall, Carl M. Urban, Brad J. Spellberg, Diane Rhee, Diane C. Halstead, Anthony W. Pasculle, and Yohei Doi

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Revision total hip arthroplasty with retained acetabular component, Muyibat A. Adelani, Nathan A. Mall, Humaa Nyazee, John C. Clohisy, Robert L. Barrack, and Ryan M. Nunley

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A prospective trial comparing FDG-PET/CT and CT to assess tumor response to cetuximab in patients with incurable squamous cell carcinoma of the head and neck, Douglas Adkins, Jessica Ley, Farrokh Dehdashti, Marilyn J. Siegel, Tanya M. Wildes, Loren Michel, Kathryn Trinkaus, and Barry A. Siegel

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Multiplexed direct genomic selection (MDiGS): a pooled BAC capture approach for highly accurate CNV and SNP/INDEL detection, David M. Alvarado, Ping Yang, Todd E. Druley, Michael Lovett, and Christina A. Gurnett

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In vivo substrates of the lens molecular chaperones αA-crystallin and αB-crystallin, Usha P. Andley, James P. Malone, and R. Reid Townsend

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Fine-mapping the HOXB region detects common variants tagging a rare coding allele: Evidence for synthetic association in prostate cancer, Gerald Andriole and et al

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Aligning objectives and assessment in responsible conduct of research instruction, Alison Antes and James M. DuBois

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Ultrasonography versus computed tomography for suspected nephrolithiasis, C. Aubin and R. T. Griffey

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The Prevention of Delirium and Complications Associated with Surgical Treatments (PODCAST) study: Protocol for an international multicentre randomised controlled trial, Michael S. Avidan, Bradley A. Fritz, Hannah R. Maybrier, Maxwell R. Muench, Krisztina E. Escallier, Yulong Chen, Arbi Ben Abdallah, and et al

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Motherhood, psychological risks, and resources in relation to alcohol use disorder: Are there differences between black and white women?, Sundari Balan, Gregory Widner, Hsing-Jung Chen, Darrell Hudson, Sarah Gehlert, and Rumi Kato Price

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The role of resting state networks in focal neocortical seizures, S. Kathleen Bandt, David T. Bundy, Ammar H. Hawasli, Kareem W. Ayoub, Mohit Sharma, Carl D. Hacker, Mrinal Pahwa, and Eric C. Leuthardt

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Conference Highlights of the 16th International Conference on Human Retrovirology: HTLV and Related Retroviruses, 26–30 June 2013, Montreal, Canada, Benoit Barbeau, John Hiscott, Ali Bazarbachi, Edgar Carvalho, Kathryn Jones, Fabiola Martin, Masao Matsuoka, Edward L. Murphy, Lee Ratner, William M. Switzer, and Toshiki Watanabe

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Prevalence of cigarette advertising and other promotional strategies at the point of sale in St Louis, Missouri: Analysis by store type and distance from a school, Joaquin Barnoya, Graham Colditz, Sarah Moreland-Russell, Julianne Cyr, Doneisha Snider, and Mario Schootman

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Red blood cell invasion by Plasmodium vivax: Structural basis for DBP engagement of DARC, Joseph D. Batchelor, Brian M. Malpede, Natalie S. Omattage, Gregory T. DeKoster, Katherine A. Henzler-Wildman, and Niraj H. Tolia

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Tax inflicts DNA damage through activation of Nitric Oxide production, Hicham H. Baydoun and Lee Ratner

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Prognostic significance of β-human chorionic gonadotropin and PAX8 expression in anaplastic thyroid carcinoma, Nils Becker, Rebecca D. Chernock, Brian Nussenbaum, and James S. Lewis Jr.

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Toxoplasma gondii merozoite gene expression analysis with comparison to the life cycle discloses a unique expression state during enteric development, Michael S. Behnke, Tiange P. Zhang, Jitender P. Dubey, and L. David Sibley

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Differential induction of TLR3-dependent innate immune signaling by closely related parasite species, Daniel P. Beiting, Lucia Peixoto, Natalie S. Akopyants, Stephen M. Beverley, E. John Wherry, David A. Christian, Christopher A. Hunter, Igor E. Brodsky, and David S. Roos

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Neural activation associated with the cognitive emotion regulation of sadness in healthy children, Andy C. Belden, Joan L. Luby, David Pagliaccio, and Deanna M. Barch

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Retinopathy and clinical outcomes in patients with type 2 diabetes mellitus, chronic kidney disease, and anemia, Natalie A. Bello, Marc A. Pfeffer, Hicham Skali, Janet B. McGill, Jerome Rossert, Kurt A. Olson, Larry Weinrauch, Mark E. Cooper, Dick de Zeeuw, Peter Rossing, John J. V. McMurray, Scott D. Solomon, and Trial to Reduce cardiovascular Events with Aranesp Therapy (TREAT) Investigators

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Mutation of the melastatin-related cation channel, TRPM3, underlies inherited cataract and glaucoma, Thomas M. Bennett, Donna S. Mackay, Carla J. Siegfried, and Alan Shiels

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Driving self-restriction and age: A study of emergency department patients, Marian E. Betz, Christopher R. Carpenter, Emma Genco, and David B. Carr

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Developmental differences in masked form priming are not driven by vocabulary growth, Adeetee Bhide, Bradley L. Schlaggar, and Kelly Anne Barnes

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Detection of a divergent Parainfluenza 4 virus in an adult patient with influenza like illness using next-generation sequencing, Seweryn Bialasiewicz, Jodie McVernon, Terry Nolan, Stephen B. Lambert, Guoyan Zhao, David Wang, Michael D. Nissen, and Theo P. Sloots

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Heteropathogenic virulence and phylogeny reveal phased pathogenic metamorphosis in Escherichia coli O2:H6, Martina Bielaszewska, Roswitha Schiller, Lydia Lammers, Andreas Bauwens, Angelika Fruth, Barbara Middendorf, M. Alexander Schmidt, Phillip I. Tarr, Ulrich Dobrindt, Helge Karch, and Alexander Mellmann

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Mutation and expression analysis in medulloblastoma yields prognostic variants and a putative mechanism of disease for i17q tumors, Gabriel A. Bien-Willner and Robi D. Mitra

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Spatial reorganization of putaminal dopamine D2-like receptors in cranial and hand dystonia, Kevin J. Black, Abraham Z. Snyder, Jonathan W. Mink, Veeral N. Tolia, Fredy J. Revilla, Stephen M. Moerlein, and Joel S. Perlmutter

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Case records of the Massachusetts General Hospital. Case 1-2014. A 32-year-old man with loss of vision and a rash, Melvin S. Blanchard, Javier M. Romero, and Mai P. Hoang

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Genome-wide identification and functional analysis of Apobec-1-mediated C-to-U RNA editing in mouse small intestine and liver, Valerie Blanc, Eddie Park, Sabine Schaefer, Melanie MIller, Yiing Lin, Susan Kennedy, Anja M. Billing, Hisham Ben Hamidane, Johannes Graumann, Ali Mortazavi, Joseph H. Nadeau, and Nicholas O. Davidson

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How to avoid microaspiration? A key element for the prevention of ventilator-associated pneumonia in intubated ICU patients, Stijn I. Blot, Jan Poelaert, and Marin Kollef

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Outcome of all-inside second-generation meniscal repair: Minimum five-year follow-up, Ljiljana Bogunovic, Lisa M. Kruse, Amanda K. Haas, Laura J. Huston, and Rick W. Wright

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The changing immune system in sepsis: Is individualized immuno-modulatory therapy the answer?, Jonathan S. Boomer, Jonathan M. Green, and Richard S. Hotchkiss

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Dual transgene expression in murine cerebellar Purkinje neurons by viral transduction in vivo, Marie K. Bosch, Jeanne M. Nerbonne, and David M. Ornitz

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Forkhead box transcription factor regulation and lipid accumulation by hepatitis C virus, Sandip K. Bose, Hangeun Kim, Keith Meyer, Nathan Wolins, Nicholas O. Davidson, and Ranjit Ray

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A new measure of fear of falling: psychometric properties of the fear of falling questionnaire revised (FFQ-R), Emily S. Bower, Julie L. Wetherell, C. C. Merz, Andrew J. Petkus, Vanessa L. Malcarne, and Eric J. Lenze

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What's new in spine surgery, Keith H. Bridwell, Paul A. Anderson, Scott D. Boden, Han Jo Kim, Alexander R. Vaccaro, and Jeffrey C. Wang

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PDE7B is a novel, prognostically significant mediator of glioblastoma growth whose expression is regulated by endothelial cells, Michael D. Brooks, Erin Jackson, Nicole M. Warrington, Jingqin Luo, Jason T. Forys, Sara Taylor, Diane D. Mao, Jeffrey R. Leonard, Albert H. Kim, David Piwnica-Worms, Robi D. Mitra, and Joshua B. Rubin

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Total knee arthroplasty after previous knee surgery, Robert H. Brophy, Benjamin L. Gray, Ryan M. Nunley, Robert L. Barrack, and John C. Clohisy

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Symptoms of pain do not correlate with rotator cuff tear severity, Robert H. Brophy, Matthew V. Smith, Rick W. Wright, and et al

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Rapid ertapenem susceptibility testing and Klebsiella pneumoniae carbapenemase phenotype detection in Klebsiella pneumoniae isolates by use of automated microscopy of immobilized live bacterial cells, Carey-Ann D. Burnham, Rachel A. Frobel, Monica L. Herrera, Brian L. Wickes, and D. J. Diekema

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De novo meningitis caused by Propionibacterium acnes in a patient with metastatic melanoma, Jason P. Burnham, Benjamin S. Thomas, Sergio E. Trevino, Erin McElvania TeKippe, Carey-Ann D. Burnham, and F. Matthew Kuhlmann

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Resting state functional connectivity in early blind humans, Harold Burton, Abraham Z. Snyder, and Marcus E. Raichle

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A cross-sectional study of differences in 6-min walk distance in healthy adults residing at high altitude versus sea level, Deirdre Caffrey, J. Jaime Miranda, Robert H. Gilman, Victor G. Davila-Roman, Lilia Cabrera, Russell Dowling, Talia Stewart, Antonio Bernabe-Ortiz, Robert Wise, Fabiola Leon-Velarde, William Checkley, and CRONICAS Cohort Study Group

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Cardiometabolic outcomes in children and adolescents following discontinuation of long-term risperidone treatment, Chadi A. Calarge, Ginger Nicol, Janet A. Schlechte, and Trudy L. Burns

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Dorsal and ventral attention systems underlie social and symbolic cueing, Alicia Callejas, Gordon L. Shulman, and Maurizio Corbetta

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miR-146a and miR-155 delineate a microRNA fingerprint associated with Toxoplasma persistence in the host brain, Dominique Cannella, Marie-Pierre Brenier-Pinchart, Laurence Braun, Jason M. van Rooyen, Alexandre Bougdour, Olivier Bastien, Michael S. Behnke, Rose-Laurence Curt, Aurelie Curt, Jeroen P.J. Saeij, L. David Sibley, Herve Pelloux, and Mohamed-Ali Hakimi

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Pervasive transcription of a herpesvirus genome generates functionally important RNAs, Susan P. Canny, Tiffany A. Reese, L. Steven Johnson, Xin Zhang, Amal Kambal, Erning Duan, Catherine Y. Liu, and Herbert W. Virgin

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Resting-state modulation of alpha rhythms by interference with angular gyrus activity, Paolo Capotosto, Claudio Babiloni, Gian Luca Romani, and Maurizio Corbetta

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Using publication metrics to highlight academic productivity and research impact, Christopher R. Carpenter, David C. Cone, and Cathy C. Sarli

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Cognitive functioning in young children with type 1 diabetes, M. A. Cato, Nelly Mauras, Jodie Ambrosino, Aiden Bondurant, Amy L. Conrad, Craig Kollman, Peiyao Cheng, Roy W. Beck, Katrina J. Ruedy, Tandy Aye, Allan L. Reiss, Neil H. White, and Tamara Hershey

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B-RAF unlocks axon regeneration, Valeria Cavalli and David Holtzman

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Beyond NK cells: the expanding universe of innate lymphoid cells, Marina Cella, Hannah Miller, and Christina Song

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Distinguishing West Nile virus infection using a recombinant envelope protein with mutations in the conserved fusion-loop, Stefan Chabierski, Luisa Barzon, Anna Papa, Matthias Niedrig, Jonathan L. Bramson, Justin M. Richner, Giorgio Palu, Michael S. Diamond, and Sebastian Ulbert

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Reassessing the impact of smoking on preeclampsia/eclampsia: Are there age and racial differences?, Jen Jen Chang, Jerome F. Strauss III, Jon P. Deshazo, Fidelma B. Rigby, David P. Chelmow, and George A. Macones

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Targeting the programmed cell death 1: Programmed cell death ligand 1 pathway reverses T cell exhaustion in patients with sepsis, Katherine Chang, Catherine Svabek, Cristina Vazquez-Guillamet, Bryan Sato, David Rasche, Strother Wilson, Paul Robbins, Nancy Ulbrandt, JoAnn Suzich, Jonathan Green, Andriani C. Patera, Wade Blair, Subramaniam Krishnan, and Richard Hotchkiss

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Oral contraceptive use and mortality after 36 years of follow-up in the Nurses' Health Study: Prospective cohort study, Brittany M. Charlton, Janet W. Rich-Edwards, Graham A. Colditz, Stacey A. Missmer, Bernard A. Rosner, Susan E. Hankinson, Frank E. Speizer, and Karin B. Michels

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Pathogenic adaptations to host-derived antibacterial copper, Kaveri S. Chaturvedi and Jeffrey P. Henderson

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Conservative fluid therapy in septic shock: An example of targeted therapeutic minimization, Catherine Chen and Marin H. Kollef

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Copy number analysis of NIPBL in a cohort of 510 patients reveals rare copy number variants and a mosaic deletion, Yu-Wei Cheng, Christopher A. Tan, Agata Minor, Kelly Arndt, Latrice Wysinger, Dorothy K. Grange, Beth A. Kozel, Nathaniel H. Robin, Darrel Waggoner, Carrie Fitzpatrick, Soma Das, and Daniela del Gaudio

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Osx-Cre targets multiple cell types besides osteoblast lineage in postnatal mice, Jianquan Chen, Yu Shi, Jenna Regan, Kannan Karuppaiah, David M. Ornitz, and Fanxin Long

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WNT7B promotes bone formation in part through mTORC1, Jianquan Chen, Xiaolin Tu, Emel Esen, Kyu Sang Joeng, Congxin Lin, Jeffrey M. Arbeit, Markus A. Ruegg, Michael N. Hall, Liang Ma, and Fanxin Long

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Rab5 isoforms orchestrate a ‘‘Division of Labor’’ in the endocytic network; Rab5C modulates Rac-mediated cell motility, Pin-I Chen, Kristine Schauer, Chen Kong, Andrew R. Harding, Bruno Goud, and Philip D. Stahl

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Cardiac miR-133a overexpression prevents early cardiac fibrosis in diabetes, Shali Chen, Prasanth Puthanveetil, Biao Feng, Scot J. Matkovich, Gerald W. Dorn II, and Subrata Chakrabarti

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Patient-controlled epidural Levobupicvacaine with or without Fentanyl for post-cesarean section pain relief, Shin-Yan Chen, Feng-Lin Liu, Yih-Giun Cherng, Shou-Zen Fan, Barbara L. Leighton, Hung-Chi Chang, and Li-Kuei Chen

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Mitochondrial genome linearization is a causative factor for cardiomyopathy in mice and Drosophila, Yun Chen, Megan Sparks, Poonam Bhandari, Scot J. Matkovich, and Gerald W. Dorn

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A case study of risk factors for lymphatic filariasis in the Republic of Congo, Cédric B. Chesnais, François Missamou, Sébastien D. Pion, Jean Bopda, Frédéric Louya, Andrew C. Majewski, Peter U. Fischer, Gary J. Weil, and Michel Boussinesq

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Pharmacologic blockade of JAK1/JAK2 reduces GvHD and preserves the graft-versus-leukemia effect, Jaebok Choi, Matthew L. Cooper, Bader Alahmari, Julie Ritchey, Lynne Collins, Matthew Holt, and John F. DiPersio

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Role of NKG2D in obesity-induced adipose tissue inflammation and insulin resistance, Jun-Jae Chung, Mary A. Markiewicz, Bojan Polic, and Andrey S. Shaw

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Telavancin for hospital-acquired pneumonia: Clinical response and 28-day survival, G. Ralph Corey, Marin H. Kollef, Andrew F. Shorr, Ethan Rubinstein, Martin E. Stryjewski, Alan Hopkins, and Steven L. Barriere

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Gene-wide analysis detects two new susceptibility genes for Alzheimer’s disease, Carlos Cruchaga, Alison M. Goate, and et al

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Viral pathogen-associated molecular patterns regulate blood-brain barrier integrity via competing innate cytokine signals, Brian P. Daniels, David W. Holman, Lillian Cruz-Orengo, Harsha Jujjavarapu, Douglas M. Durrant, and Robyn S. Klein

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Participants’ perceptions of a group based program incorporating hands-on meal preparation and pedometer-based self-monitoring in type 2 diabetes, Kaberi Dasgupta, Soghra Jarvandi, Mirella De Civita, Sabrina Pillay, Samantha Hajna, Rejeanne Gougeon, Abeer Bader, and Deborah Da Costa

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Vaccination of mice using the West Nile virus E-protein in a DNA prime-protein boost strategy stimulates cell-mediated immunity and protects mice against a lethal challenge, Marina De Filette, Silke Soehle, Sebatian Ulbert, Justin Richner, Michael S. Diamond, Alessandro Sinigaglia, Luisa Barzon, Stefan Roels, Julianna Lisziewicz, Orsolya Lorincz, and Niek N. Sanders

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Prevalence, correlates, and prognosis of peripheral artery disease in rural ecuador-rationale, protocol, and phase I results of a population-based survey: an atahualpa project-ancillary study, Oscar H. Del Brutto, Mark J. Sedler, Robertino M. Mera, Pablo R. Castillo, Elizabeth H. Cusick, Jadry A. Gruen, Kelsie J. Phelan, Victor J. Del Brutto, Mauricio Zambrano, and David L. Brown

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Mindfulness may both moderate and mediate the effect of physical fitness on cardiovascular responses to stress: A speculative hypothesis, Marcelo M.P. Demarzo, Jesus Montero-Marin, Phyllis K. Stein, Ausias Cebolla, Jaime G. Provinciale, and Javier Garcia-Campayo

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A chimeric virus-mouse model system for evaluating the function and inhibition of papain-like proteases of emerging coronaviruses, Xufang Deng, Sudhakar Agnihothram, Anna M. Mielech, Daniel B. Nichols, Michael W. Wilson, Sarah E. St. John, Scott D. Larsen, Andrew D. Mesecar, Deborah J. Lenschow, Ralph S. Baric, and Susan C. Baker

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An animal model with a cardiomyocyte-specific deletion of estrogen receptor alpha: Functional, metabolic, and differential network analysis, Sriram Devanathan, Timothy Whitehead, George G. Schweitzer, Nicole Fettig, Attila Kovacs, Kenneth S. Korach, Brian N. Finck, and Kooresh I. Shoghi

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Kidney transplantation in children, Vikas R. Dharnidharka, Paolo Fiorina, and William E. Harmon

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Vaccine-induced protection of rhesus macaques against plasma viremia after intradermal infection with a European lineage 1 strain of West Nile virus, Michael S. Diamond and et al

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Clonal architectures and driver mutations in metastatic melanomas, Li Ding, Minjung Kim, Krishna L. Kanchi, Nathan D. Dees, Charles Lu, Malachi Griffith, David Fenstermacher, Hyeran Sung, Christopher A. Miller, Brian Goetz, Michael C. Wendl, Obi Griffith, Lynn A. Cornelius, Gerald P. Linette, Joshua F. McMichael, Vernon K. Sondak, Ryan C. Fields, Timothy J. Ley, James J. Mule, Richard K. Wilson, and Jeffrey S. Weber

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Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia., L. Ding, C. Lu, R. S. Fulton, E. Mardis, R. K. Wilson, and et al