Designing small molecules to target cryptic pockets yields both positive and negative allosteric modulators

Authors

Kathryn M. Hart, Washington University School of Medicine in St. Louis
Katelyn E. Moeder, Washington University School of Medicine in St. Louis
Chris M. W. Ho, Washington University School of Medicine in St. Louis
Maxwell I. Zimmerman, Washington University School of Medicine in St. Louis
Thomas E. Frederick, Washington University School of Medicine in St. Louis
Gregory R. Bowman, Washington University School of Medicine in St. Louis

Journal

PLoS One

Publication Date

2017

Volume

12

Issue

6

Inclusive Pages

e0178678

Document Type

Open Access Publication

DOI

10.1371/journal.pone.0178678

Rights and Permissions

Hart KM, Moeder KE, Ho CMW, Zimmerman MI, Frederick TE, et al. (2017) Designing small molecules to target cryptic pockets yields both positive and negative allosteric modulators. PLOS ONE 12(6): e0178678. https://doi.org/10.1371/journal.pone.0178678

Recommended Citation

Hart, Kathryn M.; Moeder, Katelyn E.; Ho, Chris M. W.; Zimmerman, Maxwell I.; Frederick, Thomas E.; and Bowman, Gregory R., "Designing small molecules to target cryptic pockets yields both positive and negative allosteric modulators." PLoS One. 12, 6. e0178678. (2017).
https://digitalcommons.wustl.edu/open_access_pubs/5934