The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.

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Submissions from 2013

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Evolutionary genomics of the Salmonella enterica subspecies, Prerak T. Desai, Steffen Porwollik, Fred Long, Pui Cheng, Aye Wollam, Sandra W. Clifton, George M. Weinstock, and Michael McClelland

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Genomic and metabolic disposition of non-obese Type 2 Diabetic rats to increased myocardial fatty acid metabolism, Sriram Devanathan, Samuel T. Nemanich, Attila Kovacs, Nicole Fettig, Robert J. Gropler, and Kooresh I. Shoghi

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Antisense reduction of tau in adult mice protects against seizures, Sarah L. DeVos, Dustin K. Goncharoff, Guo Chen, Carey S. Kebodeaux, Kaoru Yamada, Floy R. Stewart, Dorothy R. Schuler, Susan E. Maloney, David F. Wozniak, Frank Rigo, C Frank Bennett, John R. Cirrito, David M. Holtzman, and Timothy M. Miller

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Association of gut microbiota with post-operative clinical course in Crohn’s disease, Neelendu Dey, David AW Soergel, Susanna Repo, and Steven E. Brenner

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Control of cellular Bcl-xL levels by deamidation-regulated degradation, So Hee Dho, Benjamin E. Deverman, Carlo Lapid, Scott R. Manson, Lu Gan, Jacob J. Riehm, Rajeev Aurora, Ki-Sun Kwon, and Steven J. Weintraub

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A phase 2 trial of ponatinib in Philadelphia chromosome-positive leukemias, J. DiPersio and et al

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Distinct neural signatures detected for ADHD subtypes after controlling for micro-movements in resting state functional connectivity MRI data, Nico U.F. Dosenbach, Bradley L. Schlaggar, and et al

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Body temperature patterns as a predictor of hospital-acquired sepsis in afebrile adult intensive care unit patients: A case-control study, Anne M. Drewry, Brian M. Fuller, Thomas C. Bailey, and Richard S. Hotchkiss

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Soluble oligomers are sufficient for transmission of a yeast prion but do not confer phenotype, Jennifer E. Dulle, Rachel E. Bouttenot, Lisa A. Underwood, and Heather L. True

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Low activity of select Hsp104 mutants is sufficient to propagate unstable prion variants, Jennifer E. Dulle and Heather L. True

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Genome sequences of three hpAfrica2 strains of Helicobacter pylori, Stacy S. Duncan, M Teresita Bertoli, Dangeruta Kersulyte, Pieter L. Valk, Sravya Tamma, Issy Segal, Mark S. McClain, Timothy L. Cover, and Douglas E. Berg

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IL-1R1 is required for dendritic cell-mediated T cell reactivation within the CNS during West Nile virus encephalitis, Douglas M. Durrant, Michelle L. Robinette, and Robyn S. Klein

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Physiological role of the interaction between CARMIL1 and capping protein, Marc Edwards, Yun Liang, Taekyung Kim, and John A. Cooper

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The relationship between resilience and personality traits in doctors: Implications for enhancing well being, Diane S. Eley, C. Robert Cloninger, Lucie Walters, Caroline Laurence, Robyn Synnott, and David Wilkinson

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HIV-Infected Adolescent, Young Adult and Pregnant Smokers: Important Targets for Effective Tobacco Control Programs, Gerome Escota and Nur Önen

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Katanin localization requires triplet microtubules in Chlamydomonas reinhardtii, Jessica M. Esparza, Eileen O'Toole, Linya Li, Thomas H. Giddings Jr., Benjamin Kozak, Alison J. Albee, and Susan K. Dutcher

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Retrotransposition of gene transcripts leads to structural variation in mammalian genomes, Adam D. Ewing, Tracy J. Ballinger, Dent Earl, Broad Institute Genome Sequencing and Analysis Program and Platform, Christopher C. Harris, Li Ding, Richard K. Wilson, and David Haussler

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Myocardial ablation of G protein–coupled receptor kinase 2 (GRK2) decreases ischemia/reperfusion injury through an anti-intrinsic apoptotic pathway, Qian Fan, Mai Chen, Lin Zou, Xiying Shang, Maggie Z. Huang, Michele Ciccarelli, Philip Raake, Henriette Brinks, Kurt J. Chuprun, Gerald W. Dorn II, Walter J. Koch, and Erhe Gao

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Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits, Mary F. Feitosa, Aldi T. Kraja, Michael A. Province, and et al

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Changes in auditory perceptions and cortex resulting from hearing recovery after extended congenital unilateral hearing loss, Jill B. Firszt, Ruth M. Reeder, Timothy A. Holden, Harold Burton, and Richard A. Chole

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Serological diagnosis of North American paragonimiasis by western blot using Paragonimus kellicotti adult worm antigen, Peter U. Fischer, Kurt C. Curtis, Scott M. Folk, Patricia P. Wilkins, Luis A. Marcos, and Gary J. Weil

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Transmission assessment surveys (TAS) to define endpoints for lymphatic filariasis mass drug administration: A multicenter evaluation, Peter U. Fischer, Ramakrishna U. Rao, and et al

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Dietary protein restriction inhibits tumor growth in human xenograft models of prostate and breast cancer, Luigi Fontana, Remi M. Adelaiye, Antonella L. Rastelli, Kiersten Marie Miles, Eric Ciamporcero, Valter D. Longo, Holly Nguyen, Robert Vessella, and Roberto Pili

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Optimization of routine identification of clinically relevant gram-negative bacteria by use of matrix-assisted laser desorption ionization-time of flight mass spectrometry and the bruker biotyper, Bradley A. Ford and Carey-Ann D. Burnham

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AhrC and Eep are biofilm infection-associated virulence factors in enterococcus faecalis, Kristi L. Frank, Pascale S. Guiton, Aaron M T Barnes, Dawn A. Manlas, Olivia N. Chuang-Smith, Petra L. Kohler, Adam R. Spaulding, Scott J. Hultgren, Patrick M. Schievert, and Gary M. Dunny

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Targeted versus universal decolonization to prevent ICU infection, Victoria J. Fraser and et al

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Depression as a risk factor for adverse outcomes in coronary heart disease, Kenneth E. Freedland and Robert M. Carney

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Mupirocin and chlorhexidine resistance in Staphylococcus aureus in patients with community-onset skin and soft tissue infections, Stephanie A. Fritz, Patrick G. Hogan, Bernard C. Camins, Ali J. Ainsworth, Carol Patrick, Madeline S. Martin, Melissa J. Krauss, Marcela Rodriguez, and Carey-Ann D. Burnham

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Digit Replantation: Experience of Two U.S. Academic Level-I Trauma Centers, Duretti Fufa, Ryan Calfee, Lindley Wall, Wenjing Zeng, and Charles Goldfarb

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Digit replantation: Experience of two U.S. academic level-I trauma centers, Duretti Fufa, Ryan Calfee, Lindley Wall, Wenjing Zeng, and Charles Goldfarb

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Lower tidal volume at initiation of mechanical ventilation may reduce progression to acute respiratory distress syndrome: A systematic review, Brian M. Fuller, Nicholas M. Mohr, Anne M. Drewry, and Christopher R. Carpenter

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Retinoblastoma protein prevents enteric nervous system defects and intestinal pseudo-obstruction, Ming Fu, Solange Landreville, Olga A. Agapova, Luke A. Wiley, Michael Shoykhet, J. William Harbour, and Robert O. Heuckeroth

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Muscle lipogenesis balances insulin sensitivity and strength through calcium signaling, Katsuhiko Funai, Haowei Song, Li Yin, Irfan J. Lodhi, Xiaochao Wei, Jun Yoshino, Trey Coleman, and Clay F. Semenkovich

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A pharmacogenetic versus a clinical algorithm for warfarin dosing, Brian F. Gage, Charles S. Eby, and et al

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Translocation of Saccharomyces cerevisiae Pif1 helicase monomers on single-stranded DNA, Roberto Galletto and Eric J. Tomko

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To the root of the curl: A signature of a recent selective sweep identifies a mutation that defines the Cornish Rex cat breed, Barbara Gandolfi, Hasan Alhaddad, Verena K. Affolter, Jeffrey Brockman, Jens Haggstrom, Shannon E. K. Joslin, Amanda L. Koehne, James C. Mullikin, Catherine A. Outerbridge, Wesley C. Warren, and Leslie A. Lyons

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Esophageal sphincter device for gastroesophageal reflux disease, Robert A. Ganz, Jeffrey H. Peters, Santiago Horgan, Willem A. Bemelman, Christy M. Dunst, Steven A. Edmundowicz, John C. Lipham, James D. Luketich, W. Scott Melvin, Brant K. Oelschlager, Steven C. Schlack-Haerer, C. Daniel Smith, Christopher C. Smith, Dan Dunn, and Paul A. Taiganides

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Temperament and character in the Child and Adolescent Twin Study in Sweden (CATSS): Comparison to the general population, and genetic structure analysis, Danilo Garcia, Sebastian Lundstrom, Sven Brandstrom, Maria Rastam, C. Robert Cloninger, Nora Kerekes, Thomas Nilsson, and Henrik Anckarsater

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Modeling of non-small cell lung cancer volume changes during CT-based image guided radiotherapy: patterns observed and clinical implications, Hiram A. Gay, Quendella Q. Taylor, Fumika Kiriyama, Geoffrey T. Dieck, Todd Jenkins, Paul Walker, Ron R. Allison, and Paolo Ubezio

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Sarm1-mediated axon degeneration requires both SAM and TIR interactions, Josiah Gerdts, Daniel W. Summers, Yo Sasaki, Aaron DiAntonio, and Jeffrey Milbrandt

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Adrenal myelolipoma: Operative indications and outcomes, Victoria M. Gershuni, James G. Bittner IV, Jeffrey F. Moley, and L. Michael Brunt

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Training the workforce in evidence-based public health: An evaluation of impact among US and international practitioners, Wesley S. Gibbert, Shannon M. Keating, Julie A. Jacobs, Elizabeth Dodson, Elizabeth Baker, Gunter Diem, Wayne Giles, Kathleen N. Gillespie, Vilius Grabauskas, Aushra Shatchkute, and Ross C. Brownson

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Results of the two incidence screenings in the National Lung Screening Trial, David S. Gierada and et al

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Clinical features of bacterial vaginosis in a murine model of vaginal infection with Gardnerella vaginalis, Nicole M. Gilbert, Warren G. Lewis, and Amanda L. Lewis

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Loss of DAP12 and FcRγ drives exaggerated IL-12 production and CD8(+) T cell response by CCR2(+) Mo-DCs, Grzegorz B. Gmyrek, Holly M. Akilesh, Daniel B. Graham, Anja Fuchs, Lihua Yang, Mark J. Miller, Gabriel J. Sandoval, Kathleen C. F. Sheehan, Robert D. Schreiber, Michael S. Diamond, and Wojciech Swat

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Efficiency of first-trimester uterine artery Doppler, A-disintegrin and metalloprotease 12, pregnancy-associated plasma protein A, and maternal characteristics in the prediction of preeclampsia, Katherine R. Goetzinger, Yan Zhong, Alison G. Cahill, Linda Odibo, George A. Macones, and Anthony O. Odibo

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Dopamine-dependent compensation maintains motor behavior in mice with developmental ablation of dopaminergic neurons, Judith P. Golden, Joseph A. DeMaro III, Amanda Knoten, Masato Hoshi, Elizabeth Pehek, Eugene M. Johnson Jr, Robert W. Gereau IV, and Sanjay Jain

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Transcription factors define the neuroanatomical organization of the medullary reticular formation, Paul A. Gray

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Modeling precision treatment of breast cancer, Obi L. Griffith, Malachi Griffith, and et al

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A robust prognostic signature for hormone-positive node-negative breast cancer, Obi L. Griffith, Francois Pepin, Oana M. Enache, Laura M. Heiser, Eric A. Collisson, Paul T. Spellman, and Joe W. Gray

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BRCA1 loss activates cathepsin L–mediated degradation of 53BP1 in breast cancer cells, David A. Grotsky, Ignacio Gonzalez-Suarez, Anna Novell, Martin A. Neumann, Sree C. Yaddanapudi, Monica Croke, Montserrat Martinez-Alonso, Abena B. Redwood, Sylvia Ortega-Martinez, Zhihui Feng, Enrique Lerma, Teresa Ramon y Cajal, Junran Zhang, Xavier Matias-Guiu, Adriana Dusso, and Susana Gonzalo

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Acute EBV infection masquerading as "In-situ Follicular Lymphoma": A pitfall in the differential diagnosis of this entity, Alejandro A. Gru, Friederike Kreisel, Eric Duncavage, TuDung T. Nguyen, Anjum Hassan, and John L. Frater

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Concurrent malignant melanoma and cutaneous involvement by classical hodgkin lymphoma (CHL) in a 63 year-old man, Alejandro A. Gru and Dongsi Lu

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Longitudinal changes in intracardiac repolarization lability in patients with implantable cardioverter-defibrillator, Abhilash Guduru, Jason Lansdown, Daniil Chernichenko, Ronald D. Berger, and Larisa G. Tereshchenko

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CMS: A web-based system for visualization and analysis of genome-wide methylation data of human cancers, Fei Gu, Mark S. Doderer, Yi-Wen Huang, Juan C. Roa, Paul J. Goodfellow, E. Lynette Kizer, Tim H. M. Huang, and Yidong Chen

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Enterococcus faecalis overcomes foreign body-mediated inflammation to establish urinary tract infections, Pascale S. Guiton, Thomas J. Hannan, Bradley Ford, Michael G. Caparon, and Scott J. Hultgren

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Rapamycin attenuates the development of posttraumatic epilepsy in a mouse model of traumatic brain injury, Dongjun Guo, Linghui Zeng, David L. Brody, and Michael Wong

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Reliability of clinically relevant 3D foot bone angles from quantitative computed tomography, David J. Gutekunst, Lu Liu, Tao Ju, Fred W. Prior, and David R. Sinacore

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Somatic neurofibromatosis type 1 (NF1) inactivation characterizes NF1-associated pilocytic astrocytoma, David H. Gutmann, Michael D. McLellan, Ibrahim Hussain, John W. Wallis, Lucinda L. Fulton, Robert S. Fulton, Vincent Magrini, Ryan Demeter, Todd Wylie, Cyriac Kandoth, Jeffrey R. Leonard, Abhijit Guha, Christopher A. Miller, Li Ding, and Elaine R. Mardis

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Exosomes: Looking back three decades and into the future, Clifford V. Harding, John E. Heuser, and Philip D. Stahl

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Sonographic accuracy of estimated fetal weight in twins, Lorie M. Harper, Kimberly A. Roehl, Methodius G. Tuuli, Anthony O. Odibo, and Alison G. Cahill

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Local health department use of Twitter to disseminate diabetes information, United States, Jenine K. Harris, Nancy L. Mueller, Doneisha Snider, and Debra Haire-Joshu

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Retrophylogenomics place tarsiers on the evolutionary branch of anthropoids, Gerrit Hartig, Gennady Churakov, Wesley C. Warren, Jürgen Brosius, Wojciech Makalowski, and Jürgen Schmitz

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Molecular characterization of articular cartilage from young adults with femoroacetabular impingement, Shingo Hashimoto, Muhammad Farooq Rai, Corey S. Gill, Zhiqi Zhang, Linda J. Sandell, and John C. Clohisy

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Progression of foot deformity in charcot neuropathic osteoarthropathy, Mary K. Hastings, Jeffrey E. Johnson, Michael J. Strube, Charles F. Hildebolt, Kathryn L. Bohnert, Fred W. Prior, and David R. Sinacore

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Chronic joint disease caused by persistent Chikungunya virus infection is controlled by the adaptive immune response, David W. Hawman, Kristina A. Stoermer, Stephanie A. Montgomery, Pankaj Pal, Lauren Oko, Michael S. Diamond, and Thomas E. Morrison

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Mapping functional transcription factor networks from gene expression data, Brian C. Haynes, Ezekiel J. Maier, Michael H. Kramer, Patricia I. Wang, Holly Brown, and Michael R. Brent

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The role of adiposity in cardiometabolic traits: A Mendelian randomization analysis, Andrew C. Heath, Pamela A. F. Madden, and et al

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Average is optimal: An inverted-U relationship between trial-to-trial brain activity and behavioral performance, Biyu J. He and John M. Zempel

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Determinants of beat-to-beat variability of repolarization duration in the canine ventricular myocyte: A computational analysis, Jordi Heijman, Antonio Zaza, Daniel M. Johnson, Yoram Rudy, Ralf L. M. Peeters, Paul G. A. Volders, and Ronald L. Westra

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Transcriptome analyses reveal protein and domain families that delineate stage-related development in the economically important parasitic nematodes, Ostertagia ostertagi and Cooperia oncophora, Esley Heizer, Dante S. Zarlenga, Bruce Rosa, Xin Gao, Robin B. Gasser, Jessie De Graef, Peter Geldhof, and Makedonka Mitreva

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Isolation and characterization of the herpes simplex virus 1 terminase complex, Jason D. Heming, Jamie B. Huffman, Lisa M. Jones, and Fred L. Homa

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Transcription coactivators p300 and CBP are necessary for photoreceptor-specific chromatin organization and gene expression, Anne K. Hennig, Guang-Hua Peng, and Shiming Chen

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Effects of resveratrol and SIRT1 on PGC-1α activity and mitochondrial biogenesis: A reevaluation, Kazuhiko Higashida, Sang Hyun Kim, Su Ryun Jung, Meiko Asaka, John O. Holloszy, and Dong-Ho Han

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Gene expression analysis of zebrafish melanocytes, iridophores, and retinal pigmented epithelium reveals indicators of biological function and developmental origin, Charles W. Higdon, Robi D. Mitra, and Stephen L. Johnson

Evolution and diversity of copy number variation in the great ape lineage, LaDeana W. Hillier and et al

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Coreceptor affinity for MHC defines peptide specificity requirements for TCR interaction with coagonist peptide–MHC, John A H Hoerter, Joanna Brzostek, Maxim N. Artyomov, Steven M. Abel, Javier Casas, Vasily Rybakin, Jeanette Ampudia, Carina Lotz, Janet M. Connolly, Arup K. Chakraborty, Keith G. Gould, and Nicholas R J Gascoigne

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Library-based clinical and translational research support, Kristi L. Holmes, Jennifer A. Lyon, Layne M. Johnson, Cathy C. Sarli, and Michele R. Tennant

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A successful strategy for increasing the influenza vaccination rate of healthcare workers without a mandatory policy outside of the United States: A multifaceted intervention in a Japanese tertiary care center, Hitoshi Honda, Yumiko Sato, Akinori Yamazaki, Simi Padival, Akira Kumagai, and Hilary Babcock

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Characterizing the role of brain derived neurotrophic factor genetic variation in Alzheimer’s Disease neurodegeneration, Robyn A. Honea, Carlos Cruchaga, Rodrigo D. Perea, Andrew J. Saykin, Jeffrey M. Burns, Daniel R. Weinberger, and Alison M. Goate

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CCDC65 mutation causes primary ciliary dyskinesia with normal ultrastructure and hyperkinetic cilia, Amjad Horani, Steven L. Brody, Thomas W. Ferkol, David Shoseyov, Mollie G. Wasserman, Asaf Ta-shma, Kate S. Wilson, Philip V. Bayly, Israel Amirav, Malena Cohen-Cymberknoh, Susan K. Dutcher, Orly Elpeleg, and Eitan Kerem

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LRRC6 mutation causes primary ciliary dyskinesia with dynein arm defects, Amjad Horani, Thomas W. Ferkol, David Shoseyov, Mollie G. Wasserman, Yifat S. Oren, Batsheva Kerem, Israel Amirav, Malena Cohen-Cymberknoh, Susan K. Dutcher, Steven L. Brody, Orly Elpeleg, and Eitan Kerem

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Genome-wide distribution of histone H4 Lysine 16 acetylation sites and their relationship to gene expression, Nobuo Horikoshi, Pankaj Kumar, Girdhar G. Sharma, Min Chen, Clayton R. Hunt, Kenneth Westover, Shantanu Chowdhury, and Tej K. Pandita

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Isoprenoid biosynthesis inhibition disrupts Rab5 localization and food vacuolar integrity in Plasmodium falciparum, Ruth Howe, Megan Kelly, John Jimah, Dana Hodge, and Audrey R. Odom

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Spontaneous variants of the [RNQ+] prion in yeast demonstrate the extensive conformational diversity possible with prion proteins, Vincent J. Huang, Kevin C. Stein, and Heather L. True

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Interscalene brachial plexus block for arthroscopic shoulder surgery: a systematic review, Michael S. Hughes, Matthew J. Matava, Rick W. Wright, Robert H. Brophy, and Matthew V. Smith

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Escherichia coli biofilms have an organized and complex extracellular matrix structure, Chia Hung, Yizhou Zhou, Jerome S. Pinkner, Karen W. Dodson, Jan R. Crowley, John Heuser, Matthew R. Chapman, Maria Hadjifrangiskou, Jeffrey P. Henderson, and Scott J. Hultgren

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Cutaneous Myeloid Sarcoma: Natural History and Biology of an Uncommon Manifestation of Acute Myeloid Leukemia, M. Yadira Hurley, Grant K. Ghahramani, Stephanie Frisch, Eric S. Armbrecht, Anne C. Lind, TuDung T. Nguyen, Anjum Hassan, Friederike H. Kreisel, and John L. Frater

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Improve definition of titanium tandems in MR-guided high dose rate brachytherapy for cervical cancer using proton density weighted MRI, Yanle Hu, Jacqueline Esthappan, Sasa Mutic, Susan Richardson, Hiram A. Gay, Julie K. Schwarz, and Perry W. Grigsby

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Review of the safety and efficacy of vitamin A supplementation in the treatment of children with severe acute malnutrition, Lora L. Iannotti, Indi Trehan, and Mark J. Manary

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The XLID protein PQBP1 and the GTPase Dynamin 2 define a signaling link that orchestrates ciliary morphogenesis in postmitotic neurons, Yoshiho Ikeuchi, Luis de la Torre-Ubieta, Takahiko Matsuda, Hanno Steen, Hitoshi Okazawa, and Azad Bonni

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Imaging the L-type amino acid transporter-1 (LAT1) with Zr-89 immunoPET, Oluwatayo F. Ikotun, Bernadette V. Marquez, Chaofeng Huang, Kazue Masuko, Miyamoto Daiji, Takashi Masuko, Jonathan McConathy, and Suzanne E. Lapi

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The mating competence of geographically diverse Leishmania major strains in their natural and unnatural sand fly vectors, Ehud Inbar, Natalia S. Akopyants, Melanie Charmoy, Audrey Romano, Phillip Lawyer, Dia-Eldin A. Elnaiem, Florence Kauffmann, Mourad Barhoumi, Michael Grigg, Katherine Owens, Michael Fay, Deborah E. Dobson, Jahangheer Shaik, Stephen M. Beverley, and David Sacks

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DNA damage activates a complex transcriptional response in murine lymphocytes that includes both physiological and cancer-predisposition programs, Cynthia L. Innes, Jill E. Hesse, Stela S. Palii, Beth A. Helmink, Abigail J. Holub, Barry P. Sleckman, and Richard S. Paules

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A novel carboxyl-terminal heptapeptide initiates the regulated secretion of LH from unique sub-domains of the ER, Albina Jablonka-Shariff and Irving Boime

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Survival following gamma knife radiosurgery for brain metastasis from breast cancer, Jerry J. Jaboin, Daniel J. Ferraro, Todd A. DeWees, Keith M. Rich, Michael R. Chicoine, Joshua L. Dowling, David B. Mansur, Robert E. Drzymala, Joseph R. Simpson, William J. Magnuson, Anushka H. Patel, and Imran Zoberi

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Runx transcription factors repress human and murine c-Myc expression in a DNA-binding and C-terminally dependent manner, Paejonette T. Jacobs, Li Cao, Jeremy B. Samon, Christyne A. Kane, Emmett E. Hedblom, Anne Bowcock, and Janice C. Telfer

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Barriers to colorectal cancer screening among American Indian men aged 50 or older, Kansas and Missouri, 2006-2008, Aimee S. James, Melissa K. Filippi, Christina M. Pacheco, Lance Cully, David Perdue, Won S. Choi, K. Allen Greiner, and Christina M. Daley

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Systems intervention to promote colon cancer screening in safety net settings: Protocol for a community-based participatory randomized controlled trial, Aimee S. James, Veronica Richardson, Jean S. Wang, Enola K. Proctor, and Graham A. Colditz

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Increased risk of colorectal cancer in type 2 diabetes is independent of diet quality, Soghra Jarvandi, Nicholas O. Davidson, and Mario Schootman