The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.

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Submissions from 2015

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Alzheimer disease cerebrospinal fluid biomarkers moderate baseline differences and predict longitudinal change in attentional control and episodic memory composites in the adult children study, Andrew J. Aschenbrenner, David A. Balota, Anne M. Fagan, Janet M. Duchek, Tammie L S Benzinger, and John C. Morris

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Abnormal white matter blood-oxygen-level-dependent signals in chronic mild traumatic brain injury, Serguei V. Astafiev, Gordon L. Shulman, Nicholas V. Metcalf, Jennifer Rengachary, Christine L. MacDonald, Deborah L. Harrington, Jun Maruta, Joshua S. Shimony, Jamshid Ghajar, Mithun Diwakar, Ming-Xiong Huang, Roland R. Lee, and Maurizio Corbetta

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Excess body weight increases the burden of age-associated chronic diseases and their associated health care expenditures, Vincenzo Atella, Joanna Kopinska, Gerardo Medea, Federico Belotti, Valeria Tosti, Andrea Piano Mortari, Claudio Cricelli, and Luigi Fontana

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Measuring participation for persons with mental illness: A systematic review assessing relevance of existing scales for low and middle income countries, Ganesh M. Babulal, Parul Bakhshi, Sunyata Kopriva, Sarah A. Ali, Susan A. Goette, and Jean-Francois Trani

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Physical mapping and refinement of the painted turtle genome (chrysemys picta) inform amniote genome evolution and challenge turtle-bird chromosomal conservation, Daleen Badenhorst, LaDeana W. Hillier, Robert Literman, Eugenia Elisabet Montiel, Srihari Radhakrishnan, Yingjia Shen, Patrick Minx, Daniel E. Janes, Wesley C. Warren, Scott V. Edwards, and Nicole Valenzuela

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IL-34 mediates acute kidney injury and worsens subsequent chronic kidney disease, Jea-Hyun Baek, Rui Zeng, Julia Weinmann-Menke, M.Todd Valerius, Yukihiro Wada, Amrenda K. Ajay, Marco Colonna, and Vicki R. Kelley

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Zoonotic potential of simian arteriviruses, Adam L. Bailey, Michael Lauck, Samuel D. Sibley, Thomas C. Friedrich, Jens H. Kuhn, Nelson B. Freimer, Anna J. Jasinska, Jane E. Phillips-Conroy, Clifford J. Jolly, Preston A. Marx, Cristian Apetrei, Jeffrey Rogers, Tony L. Goldberg, and David H. O'Connor

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Characteristics of tumor infiltrating lymphocyte and circulating lymphocyte repertoires in pancreatic cancer by the sequencing of T cell receptors, Xueli Bai, Qi Zhang, Song Wu, Xiaoyu Zhang, Mingbang Wang, Fusheng He, Tao Wei, Jiaqi Yang, Yu Lou, Zhiming Cai, and Tingbo Liang

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Tuberous Sclerosis complex protein 2-independent activation of mTORC1 by human cytomegalovirus pUL38, Yadan Bai, Baoqin Xuan, Haiyan Liu, Jin Zhong, Dong Yu, and Zhikang Qian

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Long-term functional recovery after facial nerve transection and repair in the rat, Caroline A. Banks, Christopher Knox, Daniel A. Hunter, Susan E. Mackinnon, Marc H. Hohman, and Tessa A. Hadlock

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The influence of age and sex on genetic associations with adult body size and shape: A large-scale genome-wide interaction study, Llida Barata, Mary F. Feitosa, Jacek Czajkowski, Jeannette Simino, Pamela A. F. Madden, Yun Ju Sung, Andrew C. Heath, Treva K. Rice, D. C. Rao, and et al.

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Rapid-Onset Obesity with Hypothalamic Dysfunction, Hypoventilation, and Autonomic Dysregulation (ROHHAD): Exome sequencing of trios, monozygotic twins and tumours, Sarah F. Barclay, Casey M. Rand, Lauren A. Borch, Lisa Nguyen, Paul A. Gray, William T. Gibson, Richard J.A. Wilson, Paul M.K. Gordon, Zaw Aung, Elizabeth M. Berry-Kravis, Diego Ize-Ludlow, Debra E. Weese-Mayer, and N. Torben Bech-Hansen

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A participatory regional partnership approach to promote nutrition and physical activity through environmental and policy change in rural Missouri, Ellen K. Barnidge, Elizabeth A. Baker, Amy Estlund, Freda Motton, Pamela R. Hipp, and Ross C. Brownson

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Ibrutinib as initial therapy for patients with chronic lymphocytic leukemia, N. L. Bartlett and et al

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Exome sequencing identifies a rare HSPG2 variant associated with familial idiopathic scoliosis, Erin E. Baschal, Cambria I. Wethey, Kandice Swindle, Robin M. Baschal, Katherine Gowan, Nelson L.S. Tang, David M. Alvarado, Gabe E. Haller, Matthew B. Dobbs, Matthew R.G. Taylor, Christina A. Gurnett, Kenneth L. Jones, and Nancy H. Miller

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In vivo creatine kinase reaction kinetics at rest and stress in type II diabetic rat heart, Adil Bashir, Andrew R. Coggan, and Robert J. Gropler

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Absolute quantification of human liver phosphorus-containing metabolites in vivo using an inhomogeneous spoiling magnetic field gradient, Adil Bashir, Robert Gropler, and Joseph Ackerman

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Mucinous adenocarcinoma of the bladder associated with long term suprapubic tube: A case report, Tyler M. Bauman, Theodora A. Potretzke, Aaron M. Potretzke, Cary L. Siegel, and Steven B. Brandes

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Inducible nitric oxide synthase mediates DNA double strand breaks in Human T-Cell Leukemia Virus Type 1-induced leukemia/lymphoma, Hicham H. Baydoun, Mathew A. Cherian, Patrick Green, and Lee Ratner

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GPR18 controls reconstitution of mouse small intestine intraepithelial lymphocytes following bone marrow transplantation, Amy M. Becker, Derrick J. Callahan, Justin M. Richner, Jaebok Choi, John F. DiPersio, Michael S. Diamond, and Deepta Bhattacharya

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The Drosophila prosecretory transcription factor dimmed is dynamically regulated in adult enteroendocrine cells and protects against Gram-negative infection, Katherine Beebe, Dongkook Park, Paul H. Taghert, and Craig A. Micchelli

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Rhoptry proteins ROP5 and ROP18 are major murine virulence factors in genetically divergent South American strains of Toxoplasma gondii, Michael S. Behnke, Asis Khan, Elvin J. Lauron, John R. Jimah, Qiuling Wang, Niraj H. Tolia, and L. David Sibley

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Genetic mapping reveals that sinefungin resistance in Toxoplasma gondii is controlled by a putative amino acid transporter locus that can be used as a negative selectable marker, Michael S. Behnke, Asis Khan, and David Sibley

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Genetic mapping reveals that sinefungin resistance in Toxoplasma gondii is controlled by a putative amino acid transporter locus that can be used as a negative selectable marker, Michael S. Behnke, Asis Khan, and L David Sibley

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Clinically early-stage CSPα mutation carrier exhibits remarkable terminal stage neuronal pathology with minimal evidence of synaptic loss, Bruno A. Benitez, Nigel J. Cairns, Robert E. Schmidt, John C. Morris, Joanne B. Norton, Carlos Cruchaga, and Mark S. Sands

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Plasma endotoxin core antibody concentration and linear growth are unrelated in rural Malawian children aged 2–5 years, Nicole Benzoni, Poonum Korpe, Chrissie Thakwalakwa, Ken Maleta, Kevin Stephenson, Micah Manary, and Mark Manary

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Immediate postoperative pain: An atypical presentation of dropped gallstones after laparoscopic cholecystectomy, Samba Binagi, Jason Keune, and Michael Awad

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Positive testing for Neisseria gonorrhoeae and Chlamydia trachomatis and the risk of pelvic inflammatory disease in IUD users, Natalia E. Birgisson, Qiuhong Zhao, Gina M. Secura, Tessa Madden, and Jeffrey F. Peipert

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Preventing unintended pregnancy: The contraceptive CHOICE project in review, Natalia E. Birgisson, Qiuhong Zhao, Gina M. Secura, Tessa Madden, and Jeffrey F. Peipert

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Selective cognitive and psychiatric manifestations in Wolfram Syndrome, Allison N. Bischoff, Angela M. Reiersen, Anna Buttlaire, Amal Al-lozi, Tasha Doty, Bess A. Marshall, Tamara Hershey, and Washington University Wolfram Syndrome Research Group

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Ciliated hepatic foregut cyst: A report of 6 cases and a review of the English literature, Katherine C. Bishop, Carmen M. Perrino, Marianna B. Ruzinova, and Elizabeth M. Brunt

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Levodopa effects on [(11)C]raclopride binding in the resting human brain, Kevin J. Black, Marilyn L. Piccirillo, Jonathan M. Koller, Tiffany Hseih, Lei Wang, and Mark A. Mintun

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GABA-A inhibition shapes the spatial and temporal response properties of Purkinje cells in the macaque cerebellum, Pablo M. Blazquez and Tatyana A. Yakusheva

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Higher throughput quantification of neutralizing antibody to herpes simplex viruses, Tamara P. Blevins, Michelle C. Mitchell, Maria Korom, Hong Wang, Yinyi Yu, Lynda A. Morrison, and Robert B. Belshe

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Genetic variants modify the effect of age on APOE methylation in the Genetics of Lipid Lowering Drugs and Diet Network study, Ingrid B. Borecki and et al

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Parent-of-origin effects of the APOB gene on adiposity in young adults, Ingrid B. Borecki, Felicia Gomez, and et al

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Intracellular FGF14 (iFGF14) is required for spontaneous and evoked firing in cerebellar Purkinje neurons and for motor coordination and balance, Marie K. Bosch, Yarimar Carrasquillo, Joseph L. Ransdell, Ajay Kanakamedala, David M. Ornitz, and Jeanne M. Nerbonne

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Behavioral, cognitive, and adaptive development in infants with autism spectrum disorder in the first 2 years of life, Kelly Botteron and et al

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MC1R gene variants and non-melanoma skin cancer: A pooled-analysis from the M-SKIP project, Anne Bowcock, Lynn Cornelius, Martha Laurin Council, and et al

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Feasibility of a randomized clinical trial for treatment of femoroacetabular impingement of the hip, Gloria N. Boye, Kerri Murray, John C. Clohisy, and Young-Jo Kim

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Volar locking-plate and kirschner-wire fixation did not differ in terms of functional outcomes after dorsally displaced distal radial fracture, Martin Boyer

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A review of gene therapy in canine and feline models of lysosomal storage disorders, Allison M. Bradbury, Brittney L. Gurda, Margret L. Casal, Katherine P. Ponder, Charles H. Vite, and Mark E. Haskins

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Joint MiRNA/mRNA expression profiling reveals rhanges consistent with development of dysfunctional corpus luteum after weight gain, Andrew P. Bradford, Kenneth Jones, Katerina Kechris, Justin Chosich, Michael Montague, Wesley C. Warren, Margaret C. May, Zain Al-Safi, Satu Kuokkanen, Susan E. Appt, and Alex J. Polotsky

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Survival outcome according to KRAS mutation status in newly diagnosed patients with stage IV non-small cell lung cancer treated with platinum doublet chemotherapy, Anna K. Brady, Jonathan D. McNeill, Brendan Judy, Joshua Bauml, Tracey L. Evans, Roger B. Cohen, Corey Langer, Anil Vachani, and Charu Aggarwal

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IMAGES IN CLINICAL MEDICINE. Gastric pneumatosis, Ann-Christina Brady and Patrick A. Dillon

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What's new in Spine Surgery, Keith H. Bridwell, Paul A. Anderson, Scott D. Boden, Han Jo Kim, Alexander Vaccaro, and Jeffrey C. Wang

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Low-order non-spatial effects dominate second-order spatial effects in the texture quantifier analysis of 18F-FDG-PET images, Frank J. Brooks and Perry W. Grigsby

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Factors associated with infection following anterior cruciate ligament reconstruction, Robert H. Brophy, Rick W. Wright, Laura J. Huston, Samuel K. Nwosu, the MOON Knee Group, and Kurt P. Spindler

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IARC monographs: 40 years of evaluating carcinogenic hazards to humans, Ross C. Brownson and et al.

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Pathogenesis of bone diseases: The role of immune system, Giacomina Brunetti, Giorgio Mori, Patrizia D'Amelio, and Roberto Faccio

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Comparison of the next-generation Xpert MRSA/SA BC assay and the GeneOhm StaphSR assay to routine culture for identification of Staphylococcus aureus and methicillin-resistant S. aureus in positive-blood-culture broths, Blake W. Buchan, Stephen Allen, Carey-Ann D. Burnham, Erin McElvania TeKippe, Thomas Davis, Michael Levi, Donna Mayne, Preeti Pancholi, Ryan F. Relich, Richard Thomson, and Nathan A. Ledeboer

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T cell metabolism drives immunity, Michael D. Buck, David O'Sullivan, and Erika L. Pearce

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How do you know it is true? integrity in research and publications: AOA critical issue, Joseph A. Buckwalter, Vernon T. Tolo, and Regis J. O'Keefe

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How do you know it is true? Integrity in research and publications, Joseph A. Buckwalter, Vernon T. Tolo, and Regis J. O'Keefe

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How do you know it is true? Integrity in research and publications, Joseph A. Buckwalter, Vernon T. Tolo, and Regis J. O'Keefe

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Dopaminergic, serotonergic, and noradrenergic deficits in Parkinson disease, Chandana Buddhala, Susan K. Loftin, Brandon M. Kuley, Nigel J. Cairns, Meghan C. Campbell, Joel S. Perlmutter, and Paul T. Kotzbauer

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Evaluating diabetes mobile applications for health literate designs and functionality, 2014, Charlene A. Caburnay, Kaitlin Graff, Jenine K. Harris, Amy McQueen, Madeleine Smith, Maggie Fairchild, and Matthew W. Kreuter

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Effects of dietary acid load on exercise metabolism and anaerobic exercise performance, Susan L. Caciano, Cynthia L. Inman, Elizabeth E. Gockel-Blessing, and Edward P. Weiss

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The pancreas anatomy conditions the origin and properties of resident macrophages, Boris Calderon, Javier A. Carrero, Stephen T. Ferris, Dorothy K. Sojka, Lindsay Moore, Slava Epelman, Kenneth M. Murphy, Wayne M. Yokoyama, Gwendalyn J. Randolph, and Emil R. Unanue

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Dynamics of EEG rhythms support distinct visual selection mechanisms in parietal cortex: A simultaneous transcranial magnetic stimulation and EEG study, Paolo Capotosto, Sara Spadone, Annalisa Tosoni, Carlo Sestieri, Gian Luca Romani, Stefania Della Penna, and Maurizio Corbetta

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Mobility and safety issues in drivers with dementia, David B. Carr and Desmond O'Neill

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Evaluating the optimal definition of abnormal first-trimester uterine artery Doppler parameters to predict adverse pregnancy outcomes, Ebony B. Carter, Katherine Goetzinger, Methodius G. Tuuli, Linda Odibo, Alison G. Cahill, George A. Macones, and Anthony O. Odibo

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Pregnancy complications as markers for subsequent maternal cardiovascular disease: Validation of a maternal recall questionnaire, Ebony B. Carter, Jennifer J. Stuart, Leslie V. Farland, Janet W. Rich-Edwards, Chloe A. Zera, Thomas F. McElrath, and Ellen W. Seely

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mTOR and MEK1/2 inhibition differentially modulate tumor growth and the immune microenvironment in syngeneic models of oral cavity cancer, Harrison Cash, Sujay Shah, Ellen Moore, Andria Caruso, Ravindra Uppaluri, Carter Van Waes, and Clint Allen

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Asthma is more severe in older adults, Mario Castro and et al.

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Clinical implications of having reduced mid forced expiratory flow rates (FEF25-75), independently of FEV1, in adult patients with asthma, Mario Castro and et al.

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A retrospective study on genetic heterogeneity within Treponema strains: Subpopulations are genetically distinct in a limited number of positions, Darina Cejkova, Michal Strouhal, Steven J. Norris, George M. Weinstock, and David Smajs

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Genomic analysis to define molecular basis of aggressiveness in a mouse model of oral cancer, Varun Chalivendra, Krishna Latha Kanchi, Michael D. Onken, Ashley E. Winkler, Elaine Mardis, and Ravindra Uppaluri

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The distribution and mutagenesis of short coding INDELs from 1,128 whole exomes, Danny Challis, Lilian Antunes, Erik Garrison, Eric Banks, Uday S. Evani, Donna Muzny, Ryan Poplin, Richard A. Gibbs, Gabor Marth, and Fuli Yu

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What’s new in shoulder and elbow surgery?, Aaron M. Chamberlain, Surena Namdari, and Jay D. Keener

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Reduction of parathyroid hormone with vitamin D supplementation in blacks: A randomized controlled trial, Paulette D. Chandler, Foluso Agboola, Kimmie Ng, Jamil B. Scott, Bettina F. Drake, Gary G. Bennett, Andrew T. Chan, Bruce W. Hollis, Karen M. Emmons, Charles S. Fuchs, and Edward L. Giovannucci

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Effects of vitamin D supplementation on C-peptide and 25-hydroxyvitamin D concentrations at 3 and 6 months, Paulette D. Chandler, Edward L. Giovannucci, Jamil B. Scott, Gary G. Bennett, Kimmie Ng, Andrew T. Chan, Bruce W. Hollis, Nader Rifai, Karen M. Emmons, Charles S. Fuchs, and Bettina F. Drake

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Impact of vitamin D supplementation on adiposity in African-Americans, P D. Chandler, J B. Scott, B F. Drake, K Ng, A T. Chan, B W. Hollis, K M. Emmons, E L. Giovannucci, C S. Fuchs, and G G. Bennett

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A latent class analysis of risk factors for acquiring HIV among men who have sex with men: implications for implementing pre-exposure prophylaxis programs, Philip A. Chan, Jennifer Rose, Justine Maher, Stacey Benben, Kristen Pfeiffer, Alexi Almonte, Joanna Poceta, Catherine E. Oldenburg, Sharon Parker, Brandon D.L Marshall, Mickey Lally, Kenneth Mayer, Leandro Mena, Rupa Patel, and Amy S. Nunn

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Epigenetic and microRNA regulation during osteoarthritis development, Di Chen, Jie Shen, and Tianqian Hui

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Structural analysis of the synthetic Duffy Binding Protein (DBP) antigen DEKnull relevant for Plasmodium vivax malaria vaccine design, Edwin Chen, Nichole D. Salinas, Francis B. Ntumngia, John H. Adams, and Niraj H. Tolia

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Aggregate blood pressure responses to serial dietary sodium and potassium intervention: Defining responses using independent component analysis, Gengsheng Chen, Lisa de las Fuentes, Chi C. Gu, Jiang He, Dongfeng Gu, Tanika Kelly, James Hixson, Cashell Jacquish, D. C. Rao, and Treva K. Rice

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Biomechanical determination of distal level for fusions across the cervicothoracic junction, Ivan Cheng, Eric B. Sundberg, Alex Iezza, Derek P. Lindsey, and K. Daniel Riew

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Abnormal mammary development in 129: STAT1-null mice is stroma-dependent, Jane Q. Chen, Hidetoshi Mori, Robert D. Cardiff, Josephine F. Trott, Russell C. Hovey, Neil E. Hubbard, Jesse A. Engelberg, Clifford G. Tepper, Brandon J. Willis, Imran H. Khan, Resmi K. Ravindran, Szeman R. Chan, Robert D. Schreiber, and Alexander D. Borowsky

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mTORC1 signaling promotes osteoblast differentiation from preosteoblasts, Jianquan Chen and Fanxin Long

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STAT1 modification improves therapeutic effects of interferons on lung cancer cells, Junjie Chen, Jialu Zhao, Lefu Chen, Nian Dong, Zhaojian Ying, Zhenzhen Cai, Dongxiang Ji, Yong Zhang, Li Dong, Yuping Li, Lei Jiang, Michael J. Holtzman, and Chengshui Chen

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Myeloid lineage skewing due to exacerbated NF-κB signaling facilitates osteopenia in Scurfy mice, T H-P Chen, G Swarnkar, G Mbalaviele, and Y Abu-Amer

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Potential functions of microRNAs in starch metabolism and development revealed by miRNA transcriptome profiling of cassava cultivars and their wild progenitor, Xin Chen, Jing Xia, Zhiqiang Xia, Hefang Zhang, Changying Zeng, Cheng Lu, Weixiong Zhang, and Wenquan Wang

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Mouse low-grade gliomas contain cancer stem cells with unique molecular and functional properties, Yi-Hsien Chen, Lucy D'Agostino McGowan, Patrick J. Cimino, Sonika Dahiya, Jeffrey R. Leonard, Da Yong Lee, and David H. Gutmann

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Neurofibromatosis-1 regulation of neural stem cell proliferation and multilineage differentiation operates through distinct RAS effector pathways, Yi-Hsien Chen, Scott M. Gianino, and David H. Gutmann

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Focal segmental glomerulosclerosis: Molecular genetics and targeted therapies, Ying Maggie Chen and Helen Liapis

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Coenzyme Q10 restores oocyte mitochondrial function and fertility during reproductive aging, Maggie Chi, Kelle H. Moley, and et al

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Associations between self-referral and health behavior responses to genetic risk information, Kurt D. Christensen, J. Scott Roberts, Brian J. Zikmund-Fisher, Sharon LR Kardia, Colleen M. McBride, Erin Linnenbringer, Robert C. Green, and REVEAL Study Group

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Cytosolic phospholipase A 2 plays a crucial role in ROS/NO signaling during microglial activation through the lipoxygenase pathway, Dennis Y. Chuang, Agnes Simonyi, Paul T. Kotzbauer, Zezong Gu, and Grace Y. Sun

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Cytosolic phospholipase A2 plays a crucial role in ROS/NO signaling during microglial activation through the lipoxygenase pathway, Dennis Y. Chuang, Agnes Simonyi, Paul T. Kotzbauer, Zezong Gu, and Grace Y. Sun

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Albumin-associated free fatty acids induce macropinocytosis in podocytes, Jun-Jae Chung, Tobias B. Huber, Markus Gödel, George Jarad, Björn Hartleben, Christopher Kwoh, Alexander Keil, Aleksey Karpitskiy, Jiancheng Hu, Christine J. Huh, Marina Cella, Richard W. Gross, Jeffrey H. Miner, and Andrey S. Shaw

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Extending reference assembly models, Deanna M. Church, Valerie A. Schneider, Karyn Meltz Steinberg, Michael C. Schatz, Aaron R. Quinlan, Chen-Shan Chin, Paul A. Kitts, Bronwen Aken, Gabor T. Marth, Michael M. Hoffman, Javier Herrero, M. Lisandra Zepeda Mendoza, Richard Durbin, and Paul Flicek

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Obesity and aerobic fitness among urban public school students in elementary, middle, and high school, B. Ruth Clark, M. Leanne White, Nathaniel K. Royer, Tamara L. Burlis, Nicholas C. DuPont, Michael Wallendorf, and Susan B. Racette

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Influence of home and school environments on specific dietary behaviors among postpartum, high-risk teens, 27 states, 2007-2009, Megan A. Clarke, Debra L. Haire-Joshu, Cynthia D. Schwarz, Rachel G. Tabak, and Corinne E. Joshu

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Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders, Paul Cliften, Jeffrey Milbrandt, and et al

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Human ​gephyrin is encompassed within giant functional noncoding yin–yang sequences, Sharlee Climer, Alan R. Templeton, and Weixiong Zhang

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Sickle cell disease: Wheeze or asthma?, Robyn T. Cohen, Elizabeth S. Klings, and Robert C. Strunk

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A twin study of breastfeeding with a preliminary genome-wide association scan, Lucia Colodro-Conde, Gu Zhu, Robert A. Power, Anjali Henders, Andrew C. Heath, Pamela A F Madden, Grant W. Montgomery, Sarah Medland, Juan R. Ordoñana, and Nicholas G. Martin

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Association between dietary patterns during pregnancy and birth size measures in a diverse population in Southern US, Uriyoán Colón-Ramos, Susan B. Racette, Jody Ganiban, Thuy G. Nguyen, Mehmet Kocak, Kecia N. Carroll, Eszter Völgyi, and Frances A. Tylavsky

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Differential mechanisms of Cantú syndrome–associated gain of function mutations in the ABCC9 (SUR2) subunit of the KATP channel, Paige E. Cooper, Monica Sala-Rabanal, Sun Joo Lee, and Colin G. Nichols