The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.

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Submissions from 2006

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Protective immune responses against West Nile virus are primed by distinct complement activation pathways, Erin Mehlhop and Michael S. Diamond

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Physical map-assisted whole-genome shotgun sequence assemblies, David Messina, Shiaw-Pyng Yang, Wesley C. Warren, John W. Wallis, LaDeana W. Hillier, Asif T. Chinwalla, and Richard K. Wilson

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Characterization of a novel porin involved in systemic Yersinia enterocolitica infection, Shirly Mildiner-Earley and Virginia L. Miller

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Development of the minimum information specification for in situ hybridization and immunohistochemistry experiments (MISFISHIE), Jason C. Mills and et al

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Biology and genome of Trichinella spiralis, Makedonka Mitreva and Douglas P. Jasmer

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Codon usage patterns in Nematoda: Analysis based on over 25 million codons in thirty-two species, Makedonka Mitreva, Michael C. Wendl, John Martin, Todd Wylie, Yong Yin, Allan Larson, John Parkinson, Robert H. Waterston, and James P. McCarter

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Analysis of IFT74 as a candidate gene for chromosome 9p-linked ALS-FTD, Parastoo Momeni, Jennifer Schymick, Shushant Jain, Mark R. Cookson, Nigel J. Cairns, Elisa Greggio, Matthew J. Greenway, Stephen Berger, Stuart Pickering-Brown, Adriano Chiò, Hon Chung Fung, David M. Holtzman, Edward D. Huey, Eric M. Wassermann, Jennifer Adamson, Michael L. Hutton, Ekaterina Rogaeva, Peter St George-Hyslop, Jeffrey D. Rothstein, Orla Hardiman, Jordan Grafman, Andrew Singleton, John Hardy, and Bryan J. Traynor

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Childhood sexual abuse and risks for licit and illicit drug-related outcomes: A twin study, Elliot C. Nelson, Andrew C. Heath, Michael T. Lynskey, Kathleen K. Bucholz, Pamela A F Madden, Dixie J. Statham, and Nicholas G. Martin

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A response to high-dose estrogen for tamoxifen, aromatase inhibitor and trastuzumab refractory HER2+ and ER+ advanced breast cancer, B. Nervi, A. Denes, and M. J. Ellis

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Genotyping of toxoplasma gondii by multiplex PCR and peptide-based serological testing of samples from infants in Poland diagnosed with congenital toxoplasmosis, Dorota Nowakowska, Iris Colon, Jack S. Remington, Michael Grigg, Elzbieta Golab, J. Wilczynski, and L. D. Sibley

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Evaluating the efficiency of using second-trimester nasal bone hypoplasia as a single or a combined marker for fetal aneuploidy, Anthony O. Odibo, Harish M. Sehdev, Laura Sproat, Claudia Parra, Linda Odibo, Linda Dunn, and George A. Macones

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Vignettes: diverse library staff offering diverse bioinformatics services, David L. Osterbur, Kristine Alpi, Catarine Canevari, Pamela M. Corley, Medha Devare, Nicola Gaedeke, Donna K. Jacobs, Peter Kirlew, Janet A. Ohles, K.T.L. Vaughan, Lili Wang, Yongchun Wu, and Renata C. Greer

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Mammalian Rad9 plays a role in telomere stability, S- and G2-phase-specific cell survival, and homologous recombinational repair, Raj K. Pandita, Girdhar G. Sharma, Andrei Laszlo, Kevin M. Hopkins, Scott Davey, Mikhail Chakhparonian, Arun Gupta, Raymund J. Wellinger, Junran Zhang, Simon N. Powell, Joseph L. Roti Roti, Howard B. Lieberman, and Tej K. Pandita

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Role of mammalian Rad9 in genomic stability and ionizing radiation response, Tej K. Pandita

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NF-κB-inducing kinase regulates selected gene expression in the Nod2 signaling pathway, Qilin Pan, Vladimir Kravchenko, Alex Katz, Shuang Huang, Masayuki Ii, John C. Mathison, Koichi Kobayashi, Richard A. Flavell, Robert D. Schreiber, David Goeddel, and Richard J. Ulevitch

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Antimalarial effects of human immunodeficiency virus type 1 protease inhibitors differ from those of the aspartic protease inhibitor pepstatin, Sunil Parikh, Jun Liu, Puran Sijwali, Jiri Gut, Daniel E. Goldberg, and Philip J. Rosenthal

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Anti-apoptotic effects of caspase inhibitors on rat intervertebral disc cells, Jon-Beom Park, In-Chul Park, Sung-Jin Park, Hyeon-Ok Jin, Jin-Kyung Lee, and K. Daniel Riew

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Genetic analyses of DSM-IV nicotine withdrawal in adult twins, Michele L. Pergadia, Andrew C. Heath, Nicholas G. Martin, and Pamela A F Madden

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Prospective measurement of function and pain in patients with non-neoplastic compression fractures treated with vertebroplasty, Heidi Prather, Linda Van Dillen, John P. Metzler, K. Daniel Riew, and Louis A. Gilula

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Ciprofloxacin-resistant gram-negative bacilli in the fecal microflora of children, Xuan Qin, Yasmin Razia, James R. Johnson, Jennifer R. Stapp, Daniel R. Boster, Treva Tsosie, Donna L. Smith, Christopher R. Braden, Kathryn Gay, Frederick J. Angulo, and Phillip I. Tarr

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A real-time PCR-based assay for detection of Wuchereria bancrofti DNA in blood and mosquitoes, Ramakrishna U. Rao, Laura J. Atkinson, Reda M.R. Ramzy, Hanan Helmy, Hoda A. Farid, Moses J. Bockarie, Melinda Susapu, Sandra J. Laney, Steven A. Williams, and Gary J. Weil

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Cytokine profiles of filarial granulomas in jirds infected with Brugia pahangi, Ramakrishna U. Rao and Thomas R. Klei

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Detection of Brugia parasite DNA in human blood by real-time PCR, Ramakrishna U. Rao, Gary J. Weil, Kerstin Fischer, Taniawati Supali, and Peter Fischer

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Expression of putative virulence factors of Escherichia coli O157:H7 differs in bovine and human infections, Rebecca A. Rashid, Tami A. Tabata, Melissa J. Oatley, Thomas E. Besser, Phillip I. Tarr, and Steve L. Moseley

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Duloxetine versus routine care in the long-term management of diabetic peripheral neuropathic pain, Joel Raskin, Timothy R. Smith, Kar Wong, Yili Lu Pritchett, Deborah N. D'Souza, Smriti Iyengar, and J. F. Wernicke

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The generation and function of soluble apoE receptors in the CNS, G William Rebeck, Mary Jo LaDu, Steven Estus, Guojun Bu, and Edwin J. Weeber

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Nerve root blocks in the treatment of lumbar radicular pain: A minimum five-year follow-up, K. Daniel Riew, Jong-Beom Park, Yong-Sun Cho, Louis Gilula, Alpesh Patel, Lawrence G. Lenke, and Keith H. Bridwell

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Nothing but skin and bone, F. Patrick Ross and Angela M. Christiano

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Unusual kinetic and structural properties control rapid assembly and turnover of actin in the parasite Toxoplasma gondii, Nivedita Sahoo, Wandy Beatty, John Heuser, David Sept, and L. David Sibley

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A Tail of multiple calcium-sensing domains, Lawrence Salkoff

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CpG-induced tyrosine phosphorylation occurs via a TLR9-independent mechanism and is required for cytokine secretion, Miguel A. Sanjuan, Navin Rao, Kuei-Tai A. Lai, Yin Gu, Siquan Sun, Anja Fuchs, Wai-Ping Fung-Leung, Marco Colonna, and Lars Karlsson

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Insulin resistance and atherosclerosis, Clay F. Semenkovich

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Geminin's double life: Chromatin connections that regulate transcription at the transition from proliferation to differentiation, Seongjin Seo and Kristen L. Kroll

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Surveillance for vancomycin-resistant enterococci: Type, rates, costs, and implications, Brooke N. Shadel, Laura A. Puzniak, Kathleen N. Gillespie, Steven J. Lawrence, Marin Kollef, and Linda M. Mundy

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Blocking monoclonal antibodies specific for mouse IFN-α/β receptor subunit 1 (IFNAR-1) from mice immunized by in vivo hydrodynamic transfection, Kathleen C F Sheehan, Koon Siew Lai, Gavin P. Dunn, Allen T. Bruce, Mark S. Diamond, Jennifer D. Heutel, Corazon Dungo-Arthur, Javier A. Carrero, J. Michael White, Paul J. Herzog, and Robert D. Schreiber

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A prospective study of differences in duodenum compared to remaining small bowel motion between radiation treatments: Implications for radiation dose escalation in carcinoma of the pancreas, Anurag K. Singh, Ryan M. Tierney, Daniel A. Low, Parag J. Parikh, Robert J. Myerson, Joseph O. Deasy, Catherine S. Wu, Gisele C. Pereira, Sasha H. Wahab, Sasa Mutic MS, Perry W. Grigsby, and Andrew J. Hope

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Genomic and metabolic studies of the impact of probiotics on a model gut symbiont and host, Justin L. Sonnenburg, Christina T. Chen, and Jeffery I. Gordon

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COG-7-deficient human fibroblasts exhibit altered recycling of Golgi proteins, Richard Steet and Stuart Kornfeld

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The role of myristoylation in the membrane association of the Lassa virus matrix protein Z, Thomas Strecker, Anna Maisa, Stephane Daffis, Robert Eichler, Oliver Lenz, and Wolfgang Garten

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The Haemophilus influenzae Type b hcsA and hcsB gene products facilitate transport of capsular polysaccharide across the outer membrane and are essential for virulence, Soila Sukupolvi-Petty, Susan Grass, and Joseph W. St. Geme III

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Choosing the best heuristic for seeded alignment of DNA sequences, Yanni Sun and Jeremy Buhler

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PKR-dependent autophagic degradation of herpes simplex virus type 1, Zsolt Talloczy, Herbert W. Virgin IV, and Beth Levine

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Cortactin has an essential and specific role in osteoclast actin assembly, Shandiz Tehrani, Roberta Faccio, Indra Chandrasekar, F. Patrick Ross, and John A. Cooper

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Altered renal tubular expression of the complement inhibitor Crry permits complement activation after ischemia/reperfusion, Joshua M. Thurman, Danica Ljubanovic, Pamela A. Royer, Damian M. Kraus, Hector Molina, Nicholas P. Barry, Gregory Proctor, Moshe Levi, and V. Michael Holers

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The alchemy of tendon repair: A primer for the (S)mad scientist, Dwight A. Towler and Richard H. Gelberman

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Endocytosis of cadherin from intracellular junctions is the driving force for cadherin adhesive dimer disassembly, Regina B. Troyanovsky, Eugene P. Sokolov, and Sergey M. Troyanovsky

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Blocking airway mucous cell metaplasia by inhibiting EGFR antiapoptosis and IL-13 transdifferentiation signals, Jeffrey W. Tyner, Edy Y. Kim, Kyotaro Ide, Mark R. Pelletier, William T. Roswit, Jeffrey D. Morton, John T. Battaile, Anand C. Patel, G. Alexander Patterson, Mario Castro, Melanie S. Spoor, Yingjian You, Steven L. Brody, and Michael Holtzman

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Alpha-gliadin genes from the A, B, and D genomes of wheat contain different sets of celiac disease epitopes, Teun WJM van Herpen, Svetlana V. Goryunova, Johanna van der Schoot, Makedonka Mitreva, Elma Salentijn, Oscar Vorst, Martijn F. Schenk, Peter A. van Veelen, Frits Koning, Loek JM van Soest, Ben Vosman, Dirk Bosch, Rob J. Hamer, Luud JWJ Gilissen, and Marinus JM Smulders

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Validation of string test for diagnosis of Helicobacter pylon infections, Billie Velapatino, Jacqueline Balqui, Robert H. Gilman, Alejandro Bussalleu, Willi Quino, S. Alison Finger, Livia Santivanez, Phabiola Herrera, Alejandro Piscoya, Jose Valdiva, Jaime Cok, and Douglas E. Berg

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Identification of non-dot/icm suppressors of the Legionella pneumophila △dotL lethality phenotype, Carr D. Vincent, Benjamin A. Buscher, Jonathan R. Friedman, Lee Anne Williams, Patrick Bardill, and Joseph P. Vogel

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Genetic influences on free and cued recall in long-term memory tasks, Heather E. Volk, Kathleen B. McDermott, Henry L. Roediger III, and Richard D. Todd

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Las noticias de Madrid (News from Madrid), Suzanne Elizabeth Wahrle

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A steganalysis-based approach to comprehensive identification and characterization of functional regulatory elements, Guandong Wang and Weixiong Zhang

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Epimorphin-/- mice have increased intestinal growth, decreased susceptibility to dextran sodium sulfate colitis, and impaired spermatogenesis, Yuan Wang, Lihua Wang, Hristo Iordanov, Elzbieta A. Sweitlicki, Qun Zheng, Shujun Jiang, Yuzhu Tang, Marc S. Levin, and Deborah C. Rubin

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A multicenter intervention to prevent catheter-associate bloodstream infections, David K. Warren, Sara E. Cosgrove, Daniel J. Diekema, Gianna Zuccotti, Michael W. Climo, Maureen K. Bolon, Jerome I. Tokars, Gary A. Noskin, Edward S. Wong, Kent A. Sepkowitz, Loreen A. Herwaldt, Trish M. Perl, Steven L. Solomon, and Victoria J. Fraser

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Epidemiology of methicillin-resistant Staphylococcus aureus colonization in a surgical intensive care unit, David K. Warren, Rebecca M. Guth, Craig M. Coopersmith, Liana R. Merz, Jeanne E. Zack, and Victoria J. Fraser

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Preventing catheter-associated bloodstream infections: A survey of policies for insertion and care of central venous catheters from hospitals in the prevention epicenter program, David K. Warren, Deborah S. Yokoe, Michael W. Climo, Loreen A. Herwaldt, Gary A. Noskin, Gianna Zuccotti, Jermone I. Tokars, Trish M. Perl, and Victoria J. Fraser

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A general coverage theory for shotgun DNA sequencing, Michael C. Wendl

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The demographic and morphological features of rotator cuff disease: A comparison of asymptomatic and symptomatic shoulders, Ken Yamaguchi, Konstantinos Ditsios, William D. Middleton, Charles F. Hildebolt, Leesa M. Galatz, and Sharlene A. Teefey

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Harpin mediates cell aggregation in Erwinia chrysanthemi 3937, Mee-Ngan Yap, Clemencia M. Rojas, Ching-Hong Yang, and Amy O. Charkowski

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A eukaryotic capsular polysaccharide is synthesized intracellularly and secreted via exocytosis, Aki Yoneda and Tamara L. Doering

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Nucleophosmin is essential for ribosomal protein L5 nuclear export, Yue Yu, Leonard B. Maggi Jr., Suzanne N. Brady, Anthony J. Apicelli, Mu-Shui Dai, Hua Lu, and Jason D. Weber

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Slo3 K+ channels: Voltage and pH dependence of macroscopic currents, Xue Zhang, Xuhui Zeng, and Christopher J. Lingle

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pH-regulated Slo3 K+ channels: Properties of unitary currents, Xue Zhang, Xuhui Zeng, Xiao-Ming Xia, and Christopher J. Lingle

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The fidelity of DNA synthesis by yeast DNA polymerase zeta alone and with accessory proteins, Xuejun Zhong, Parie Garg, Stephanie A. Nick McElhinny, Carrie M. Stith, Grace E. Kissling, Peter M.J. Burgers, and Thomas A. Kunkel

Submissions from 2005

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CD36 may determine our desire for dietary fats, Nada A. Abumrad

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Low ambient O2 enhances ureteric bud branching in vitro, Tetsu Akimoto, Marc R. Hammerman, and Eiji Kusano

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Comparison of holding strength of suture anchors for hepatic and renal parenchyma, Caroline D. Ames, Juan M. Perrone, Alison J. Frisella, Kevin Morrissey, and Jaime Landman

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Preclinical and clinical performance of the Efoora test, a rapid test for detection of human immunodeficiency virus-specific antibodies, Max Q. Arens, Linda M. Mundy, and et al

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NF-κB-inducing kinase controls lymphocyte and osteoclast activities in inflammatory arthritis, Kunihiko Aya, Muhammad Alhawagri, Amanda Hagen-Stapleton, Hideki Kitaura, Osami Kanagawa, and Deborah Veis Novack

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Genetic Analysis Workshop 14: Microsatellite and single-nucleotide polymorphism marker loci for genome-wide scans, Joan E. Bailey-Wilson, Laura Almasy, Mariza de Andrade, Julia Bailey, Heike Bickeböller, Heather J. Cordell, E Warwick Daw, Lynn Goldin, Ellen L. Goode, Courtney Gray-McGuire, Wayne Hening, Gail Jarvik, Brion S. Maher, Nancy Mendell, Andrew D. Paterson, John Rice, Glen Satten, Brian Suarez, Veronica Vieland, Marsha Wilcox, Heping Zhang, Andreas Ziegler, and Jean W. MacCluer

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FHL2 inhibits the activated osteoclast in a TRAF6-dependent manner, Shuting Bai, Hideki Kitaura, Haibo Zhao, Ju Chen, Judith M. Muller, Roland Schule, Bryant Darnay, Deborah V. Novack, Patrick Ross, and Steven L. Teitelbaum

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Eukaryotic UDP-galactopyranose mutase (GLF Gene) in microbial and metazoal pathogens, Stephen M. Beverley, Katherine L. Owens, Melissa Showalter, Cara L. Griffith, Tamara L. Doering, Victoria C. Jones, and Michael R. McNeil

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Phenotypic and molecular analysis of tellurite resistance among enterohemorrhagic Escherichia coli O157:H7 and sorbitol-fermenting O157:NM clinical isolates, Martina Bielaszewska, Phillip I. Tarr, Helge Karch, Wenlan Zhang, and Werner Mathys

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Molecular profiling and phenotype analysis of Escherichia coli O26:H11 and O26:NM: Secular and geographic consistency of enterohemorrhagic and enteropathogenic isolates, Martina Bielaszewska, Wenlan Zhang, Phillip I. Tarr, Anne-Katharina Sonntag, and Helge Karch

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Targeted deletion of the murine apobec-1 complementation factor (acf) gene results in embryonic lethality, Valerie Blanc, Jeffrey O. Henderson, Elizabeth P. Newberry, Susan Kennedy, Jianyang Luo, and Nicholas O. Davidson

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The ethics and politics of stem cell research, James C. Bobrow

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An interstitial deletion-insertion involving chromosomes 2p25.3 and Xq27.1, near SOX3, causes X-linked recessive hypoparathyroidism, Michael R. Bowl, Andrew Nesbit, Brian Harding, Elaine Levy, Andrew Jefferson, Emanuela Volpi, Karine Rizzoti, Robin Lovell-Badge, David Schlessinger, Michael P. Whyte, and Rajesh V. Thakker

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Objectives of undergraduate medical education in musculoskeletal surgery and medicine, Martin I. Boyer

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Anti-Aβ antibody treatment promotes the rapid recovery of amyloid-associated neuritic dystrophy in PDAPP transgenic mice, Robert P. Brendza, Brain J. Bacskai, John R. Cirrito, Kelly A. Simmons, Jesse M. Skoch, William E. Klunk, Chester A. Mathis, Kelly R. Bales, Steven M. Paul, Bradley T. Hyman, and David M. Holtzman

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What's new in spine surgery, Keith H. Bridwell, Paul A. Anderson, Scott D. Boden, Alexander R. Vaccaro, and Jeffrey C. Wang

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The DotL protein, a member of the TraG-coupling protein family, is essential for viability of Legionella pneumophila strain Lp02, Benjamin A. Buscher, Gloria M. Conover, Jennifer L. Miller, Sinae A. Vogel, Stacey N. Meyers, Ralph R. Isberg, and Joseph P. Vogel

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Replication protein A-directed unloading of PCNA by the Ctf18 cohesion establishment complex, Goran O. Bylund and Peter M. J. Burgers

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The pleckstrin homology domain-containing protein CKIP-1 is involved in regulation of cell morphology and the actin cytoskeleton and interaction with actin capping protein, David A. Canton, Mary Ellen K. Olsten, Kyoungtae Kim, Amanda Doherty-Kirby, Gilles Lajoie, John A. Cooper, and David W. Litchfield

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Antioxidant supplementation for the prevention of kwashiorkor in Malawian children: Randomised, double blind, placebo controlled trial, Heather Ciliberto, Michael Ciliberto, Andree Briend, Per Ashorn, Dennis Bier, and Mark Manary

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P-glycoprotein deficiency at the blood-brain barrier increases amyloid-β deposition in an Alzheimer disease mouse model, John R. Cirrito, Rashid Deane, Anne M. Fagan, Michael L. Spinner, Maia Parsadanian, Mary Beth Finn, Hong Jiang, Julie L. Prior, Abhay Sagare, Kelly R. Bales, Steven M. Paul, Berislav V. Zlokovic, David Piwinca-Worms, and David M. Holtzman

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Periacetabular osteotomy for the treatment of severe acetabular dysplasia, John C. Clohisy, Susan E. Barrett, J. Eric Gordon, Eliana D. Delgado, and Perry L. Schoenecker

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Architecture and adhesive activity of the Haemophilus influenzae Hsf adhesin, Shane E. Cotter, Hye-Jeong Yeo, Twyla Juehne, and Joseph W. St. Geme III

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Identification of functional transcription factor binding sites using closely related Saccharomyces species, Scott W. Doniger, Juyoung Huh, and Justin C. Fay

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CD36 deficiency impairs intestinal lipid secretion and clearance of chylomicrons from the blood, Victor A. Drover, Mohammad Ajmal, Fatiha Nassir, Nicholas O. Davidson, Andromeda M. Nauli, Daisy Sahoo, Patrick Tso, and Nada A. Abumrad

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Use of several inducer and substrate antibiotic combinations in a disk approximation assay format to screen for AmpC induction in patient isolates of Pseudomonas aeruginosa, Enterobacter spp., Citrobacter spp., and Serratia spp., W. Michael Dunne Jr. and Daniel J. Hardin

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Microsatellites versus single-nucleotide polymorphisms in linkage analysis for quantitative and qualitative measures, Gerald Dunn, Anthony L. Hinrichs, Sarah Bertelsen, Carol H. Jin, John SK Kauwe, Brian K. Suarez, and Laura J. Bierut

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A model of the statistical power of comparative genome sequence analysis, Sean R. Eddy

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‘‘Antedisciplinary’’ science, Sean R. Eddy

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Gene finding in the chicken genome, Eduardo Eyras, Alexandre Reymond, Robert Castelo, Jacqueline M. Bye, Francisco Camara, Paul Flicek, Elizabeth J. Huckle, Genis Parra, David D. Shteynberg, Carine Wyss, Jane Rogers, Stylianos E. Antonarakis, Ewan Birney, Roderic Guigo, and Michael R. Brent

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Effects of combined diethylcarbamazine and albendazole treatment of bancroftian filariasis on parasite uptake and development in Culex pipiens L., Hoda A. Farid; Ragaa E. Hammad; Marah M. Hassan; Reda M.R, Ramzy; Maged El Setouhy; and Gary J. Weil

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Evidence for domesticated and wild populations of saccharomyces cerevisiae, Justin C. Fay and Joseph A. Benavides

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The LIM protein Ajuba influences interleukin-1-induced NF-κB activation by affecting the assembly and activity of the protein kinase Cζ/p62/TRAF6 signaling complex, Yungfeng Feng and Gregory D. Longmore

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Dominant negative effects of the AML1/ETO fusion oncoprotein, Timothy S. Fenske, Gina Pengue, and Timothy A. Graubert

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Normal cell cycle and checkpoint responses in mice and cells lacking Cdc25B and Cdc25C protein phosphatases, Angela M. Ferguson, Lynn S. White, Peter J. Donovan, and Helen Piwnica-Worms