The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.

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Submissions from 2004

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Use of an intramedullary rod for treatment of congenital pseudarthrosis of the tibia: A long-term follow-up study, Matthew B. Dobbs, Margaret M. Rich, J. Eric Gordon, Deborah A. Szymanski, and Perry L. Schoenecker

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Factors Predictive of Outcome after Use of the Ponseti Method for the Treatment of Idiopathic Clubfeet, Matthew B. Dobbs, J. R. Rudzki, Derek B. Purcell, Tim Walton, Kristina R. Porter, and Christina A. Gurnett

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Evaluation of several lightweight stochastic context-free grammars for RNA secondary structure prediction, Robin D. Dowell and Sean R. Eddy

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Protective role of interleukin-6 during Yersinia enterocolitica infection is mediated through the modulation of inflammatory cytokines, Peter H. Dube, Scott A. Handley, James Lewis, and Virginia L. Miller

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Accurate Identification of adverse outcomes after cervical spine surgery, Charles C. Edwards II, Yekaterina Karpitskaya, Chuck Cha, John G. Heller, Carl Lauryssen, S. Timothy Yoon, and K. Daniel Riew

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RNAi-mediated Hip1R silencing results in stable association between the endocytic machinery and the actin assembly machinery, Åsa E.Y. Engqvist-Goldstein, Claire X. Zhang, Sebastien Carreno, Consuelo Barroso, John E. Heuser, and David G. Drubin

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Population genetic variation in gene expression is associated with phenotypic variation in Saccharomyces cerevisiae, Justin C. Fay, Heather L. McCullough, Paul D. Sniegowski, and Michael B. Eisen

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Analysis of Human mRNAs With the Reference Genome Sequence Reveals Potential Errors, Polymorphisms, and RNA Editing, Terrence S. Furey, Mark Diekhans, Yontao Lu, Tina A. Graves, Lachlan Oddy, Jennifer Randall-Maher, LaDeana W. Hillier, Richard K. Wilson, and David Haussler

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Langerhans cell histiocytosis of the spine in children: Long-term follow-up, Sumeet Garg, Samir Mehta, and John P. Dormans

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Novel transcription regulatory elements in Caenorhabditis elegans muscle genes, Debraj GuhaThakurta, Lawrence A. Schriefer, Robert H. Waterston, and Gary D. Stormo

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Dynamics of the IRE RNA hairpin loop probed by 2-aminopurine fluorescence and stochastic dynamics simulations, Kathleen B. Hall and Jeremy Williams

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Population genetic analysis of Bartonella bacilliformis isolates from areas of Peru where Carrion's disease is endemic and epidemic, Tina M. Hambuch, Scott A. Handley, Barbara Ellis, Judith Chamberlin, Sofia Romero, and Russell Regnery

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Pancreas and kidney transplantation using embryonic donor organs, Marc R. Hammerman

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Characterization of Oral Yersinia enterocolitica infection in three different strains of inbred mice, Scott A. Handley, Peter H. Dube, Paula A. Revell, and Virginia L. Miller

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Human intraocular penetration pharmacokinetics of moxifloxacin 0.5% via topical and collagen shield routes of administration, Seenu M. Hariprasad, William F. Mieler, Gaurav K. Shah, Kevin J. Blinder, Rajendra S. Apte, Nancy M. Holekamp, Matthew A. Thomas, Jingduan Chi, and Randall A. Prince

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SH2D1A regulates T-dependent humoral autoimmunity, Jonathan D. Hron, Liron Caplan, Andrea J. Gerth, Pamela L. Schwartzberg, and Stanford L. Peng

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Genomic instability and enhanced radiosensitivity in Hsp70.1- and Hsp70.3-deficient mice, Clayton R. Hunt, David J. Dix, Girdhar G. Sharma, Raj K. Pandita, Arun Gupta, Margo Funk, and Tej K. Pandita

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Duplex doppler sonographic assessment of the effects of diethylcarbamazine and albendazole therapy on adult filarial worms and adjacent host tissues in bancroftian filariasis, Omar Hussein, Maged El Setouhy, Ehab S. Ahmed, Amr M. Kandil, Reda M.R. Ramzy, Hanan Helmy, and Gary J. Weil

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Estrogen-related receptor α directs peroxisome proliferator-activated receptor α signaling in the transcriptional control of energy metabolism in cardiac and skeletal muscle, Janice M. Huss, Ines Pineda Torra, Bart Staels, Vincent Giguere, and Daniel P. Kelly

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The association of radial deficiency with thumb hypoplasia, Michelle A. James, Hillary D. Green, H. Relton McCarroll Jr., and Paul R. Manske

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Residents should not independently perform focused abdominal sonography for trauma after 10 training examinations, Timothy Jang, Sanford Sineff, Rosanne Naunheim, and Chandra Aubin

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Evolutionary dynamics of insertion sequences in Helicobacter pylori, Awdhesh Kalia, Asish K. Mukhopadhyay, Giedrius Dailide, Yoshiyki Ito, Takeshi Azuma, Benjamin C. Y. Wong, and Douglas E. Berg

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Regulatory network connecting two glucose signal transduction pathways in saccharomyces cerevisiae, Aneta Kaniak, Zhixiong Xue, Daniel Macool, Jeong-Ho Kim, and Mark Johnston

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Thermodynamic phase plane analysis of ventricular contraction and relaxation, Mustafa Karamanoglu and Sándor J. Kovács

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A mutation in a functional Sp1 binding site of the telomerase RNA gene (hTERC) promoter in a patient with Paroxysmal Nocturnal Haemoglobinuria, W Nicol Keith, Tom Vulliamy, Jiangqin Zhao, Cem Ar, Can Erzik, Alan Bilsland, Birsen Ulku, Anna Marrone, Philip J. Mason, Monica Bessler, Nedime Serakinci, and Inderjeet Dokal

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Survey of knowledge, beliefs, and practices of neonatal intensive care unit healthcare workers regarding nosocomial infections, central venous catheter care, and hand hygiene, Allison M. Kennedy, Alexis M. Elward, and Victoria J. Fraser

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Sequence organization and insertion specificity of the novel chimeric ISHp609 transposable element of Helicobacter pylori, Dangeruta Kersulyte, Awdesh Kalia, MaoJun Zhang, Hae-Kyung Lee, Dharmalingam Subramaniam, Levute Kiuduliene, and Henrika Chalkauskas

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Interferon-inducible ubiquitin E2, Ubc8, is a conjugating enzyme for protein ISGylation, Keun Il Kim, Nadia V. Giannakopoulos, Herbert W. Virgin, and Dong-Er Zhang

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Capping protein binding to actin in yeast: biochemical mechanism and physiological relevance, Kyoungtae Kim, Atsuko Yamashita, Martin A. Wear, Yuichiro Maéda, and John A. Cooper

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Trafficking of plasmepsin II to the food vacuole of the malaria parasite Plasmodium falciparum, Michael Klemba, Wandy Beatty, Ilya Gluzman, and Daniel E. Goldberg

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Evaluation of a multiplexed bead assay for assessment of Epstein-Barr virus immunologic status, J. S. Klutts, R. S. Liao, W. M. Dunne Jr., and A. M. Gronowski

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Genetic effects on alcohol dependence risk : Re-evaluating the importance of psychiatric and other heritable risk factors, Valerie S. Knopik, Andrew C. Heath, Pamela A F Madden, Kathleen K. Bucholz, Wendy S. Slutske, Elliot C. Nelson, Dixie Statham, John B. Whitfield, and Nicholas G. Martin

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Nerve-independent formation of a topologically complex postsynaptic apparatus, Terrance T. Kummer, Thomas Misgeld, Jeff W. Lichtman, and Joshua R. Sanes

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Molecular basis of inward rectification: Polyamine interaction sites located by combined channel and ligand mutagenesis, Harley T. Kurata, L. Revell Phillips, Thierry Rose, Gildas Loussouarn, Stefan Herlitze, Hariolf Fritzenschaft, Decha Enkvetchakul, Colin G. Nichols, and Thomas Baukrowitz

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Recombinant antigen-based antibody assays for the diagnosis and surveillance of lymphatic filariasis – a multicenter trial, Patrick J. Lammie, Gary Weil, Rahman Noordin, Perumal Kaliraj, Cathy Steel, David Goodman, Vijaya B. Lakshmikanthan, and Eric Ottesen

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Potentiation of C1 esterase inhibitor by StcE, a metalloprotease secreted by escherichia coli O157:H7, Wyndham W. Lathem, Tessa Bergsbaken, and Rodney A. Welch

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Early growth response gene 1–mediated apoptosis Is essential for transforming growth factor β1–induced pulmonary fibrosis, Chun Geun Lee, Soo Jung Cho, Min Jong Kang, Svetlana P. Chapoval, Patty J. Lee, Paul W. Noble, Teshome Yehualaeshet, Binfeng Lu, Richard A. Flavell, Jeffrey Milbrandt, Robert J. Homer, and Jack A. Elias

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The PmrA-regulated pmrC gene mediates phosphoethanolamine modification of lipid A and polymyxin resistance in Salmonella enterica, Hyunwoo Lee, Fong-Fu Hsu, John Turk, and Eduardo A. Groisman

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Amyloid-beta peptide induces oligodendrocyte death by activating the neutral sphingomyelinase-ceramide pathway, Jiunn-Tay Lee, Jan Xu, Jin-Moo Lee, Grace Ku, Xianlin Han, Ding-I Yang, Shawei Chen, and Chung Y. Hsu

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P Pilus assembly motif necessary for activation of the CpxRA pathway by PapE in Escherichia coli, Yvonne M. Lee, Patricia A. DiGiuseppe, Thomas J. Silhavy, and Scott J. Hultgren

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Defining nicotine dependence for genetic research: Evidence from Australian twins, Christina N. Lessov, Nicholas G. Martin, Dixie J. Statham, Alexandre A. Todorov, Wendy S. Slutske, Kathleen K. Bucholz, Andrew C. Heath, and Pamela A F Madden

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Antibody responses to Brugia malayi antigens induced by DNA vaccination, Ben-Wen Li, Amy Rush, Shaorong R. Zhang, Kurt C. Curtis, and Gary J. Weil

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Active inhibition of plasma cell development in resting B cells by microphthalmia-associated transcription factor, Ling Lin, Andrea J. Gerth, and Stanford L. Peng

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Information assessment on predicting protein-protein interactions, Nan Lin, Baolin Wu, Ronald Jansen, Mark Gerstein, and Hongyu Zhao

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The C-terminal fragment of the internal 110-kilodalton passenger domain of the Hap protein of nontypeable Haemophilus influenzae is a potential vaccine candidate, Dai-Fang Liu, Kathryn W. Mason, Maria Mastri, Mehran Pazirandeh, David Cutter, Doran L. Fink, Joseph W. St. Geme III, Duzhang Zhu, and Bruce A. Green

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Basic helix-loop-helix proteins bind to TrkB and p21(Cip1) promoters linking differentiation and cell cycle arrest in neuroblastoma cells, Yuhui Liu, Mario Encinas, Joan X. Comella, Marti Aldea, and Carme Gallego

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MITF links differentiation with cell cycle arrest in melanocytes by transcriptional activation of INK4A, Amy E. Loercher, Elizabeth M.H. Tank, Rachel B. Delston, and J. William Harbour

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Differentiation between septic arthritis and transient synovitis of the hip in children with clinical prediction algorithms, Scott J. Luhmann, Angela Jones, Mario Schootman, J. Eric Gordon, Perry L. Schoenecker, and Jan D. Luhmann

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Neuropsychological consequences of regular marijuana use: A twin study, M. J. Lyons, J. L. Bar, M. S. Panizzon, R. Toomey, S. Eisen, H. Xian, and M. T. Tsuang

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Role for serine protease HtrA (DegP) of streptococcus pyogenes in the biogenesis of virulence factors SpeB and the hemolysin streptolysin S, William R. Lyon and Michael G. Caparon

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Evidence for neural effects of repetition that directly correlate with behavioral priming, Luigi Maccotta and Randy L. Buckner

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A missense mutation in the γD crystallin gene (CRYGD) associated with autosomal dominant "coral-like" cataract linked to chromosome 2q, Donna S. Mackay, Usha P. Andley, and Alan Shiels

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Fosmid-based physical mapping of the Histoplasma capsulatum genome, Vincent Magrini, Wesley C. Warren, John Wallis, William E. Goldman, Jian Xu, Elaine R. Mardis, and John D. McPherson

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Vav GEFs are required for beta2 integrin-dependent functions of neutrophils, M. Angelica Martinez Gakidis, Xavier Cullere, Timothy Olson, Julie L. Wilsbacher, Bin Zhang, Sheri L. Moores, Klaus Ley, Wojciech Swat, Tanya Mayadas, and Joan S. Brugge

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Multilocus sequence typing of Streptococcus pyogenes representing most known emm types and distinctions among subpopulation genetic structures, Karen McGregor, Brian G. Spratt, Awdhesh Kalia, Alicia Bennett, Nicole Bilek, Bernard Beall, and Debra E. Bessen

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Novel 180- and 480-base-pair insertions in African and African-American strains of Helicobacter pylori, Shannon L. McNulty, Beth M. Mole, Daiva Dailidiene, Issy Segal, Reid Ally, Rajesh Mistry, Ousman Secka, Richard A. Adegbola, Julian E. Thomas, Erik M. Lenarcic, Richard M. Peek Jr, Douglas E. Berg, and Mark H. Forsyth

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Effects of an antibiotic cycling program on antibiotic prescribing practices in an intensive care unit, Liana R. Merz, David K. Warren, Marin H. Kollef, and Victoria J. Fraser

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An ORFeome-based analysis of human transcription factor genes and the construction of a microarray to interrogate their expression, David N. Messina, Jarret Glasscock, Warren Gish, and Michael Lovett

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Structural basis for the restoration of TCR recognition of an MHC allelic variant by peptide secondary anchor substitution, Michael J. Miley, Ilhem Messaoudi, Beatrix M. Metzner, Yudong Wu, Janko Nikolich-Žugich, and Daved H. Fremont

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Comparative Genomics of Gene Expression in the Parasitic and Free-Living Nematodes Strongyloides stercoralis and Caenorhabditis elegans, Makedonka Mitreva, James P. McCarter, John Martin, Mike Dante, Todd Wylie, Brandi Chiapelli, Deana Pape, Sandra W. Clifton, Thomas B. Nutman, and Robert H. Waterston

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Dinitroanilines bind α-tubulin to disrupt microtubules, Naomi S. Morrissette, Arpita Mitra, David Sept, and L. David Sibley

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Correlation of cerebrospinal fluid (CSF) cell counts and elevated CSF protein levels with enterovirus reverse transcription-PCR results in pediatric and adult patients, William S. Mulford, Richard S. Buller, Max Q. Arens, and Gregory A. Storch

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Antimicrobial susceptibility of Helicobacter pylori strains isolated in Bangladesh, Shamsun Nahar, Asish K. Mukhopadhyay, Rasel Khan, Mian Mashhud Ahmad, Simanti Datta, Santanu Chattopadhyay, Swapan Chandra Dhar, Shafiqul Alam Sarker, Lars Engstrand, Douglas E. Berg, Balakrish Nair, and Motiur Rahman

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Fog-2 and the evolution of self-fertile hermaphroditism in caenorhabditis, Sudhir Nayak, Johnathan Goree, and Tim Schedl

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Electrohydraulic high-energy shock-wave treatment for chronic plantar fasciitis, John A. Ogden, Richard G. Alvarez, Richard L. Levitt, Jeffrey E. Johnson, and Marie E. Marlow

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Role of the hydrophobic domain in targeting caveolin-1 to lipid droplets, Anne G. Ostermeyer, Lynne T. Ramcharan, Youchun Zeng, Douglas M. Lublin, and Deborah A. Brown

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Prevention and management of iatrogenic flatback deformity, Benjamin K. Potter and Lawrence G. Lenke

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Propagation of diffuse light in a turbid medium with multiple spherical inhomogeneities, Vitaliy N. Pustovit and Vadim A. Markel

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A cost-benefit analysis of gown use in controlling vancomycin-resistant Enterococcus transmission: Is it worth the price?, Laura A. Puzniak, Kathleen N. Gillespie, Terry Leet, Marin Kollef, and Linda M. Mundy

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Has the epidemiology of nosocomial candidemia changed?, Laura Puzniak, Steven Teutsch, William Powderly, and Louis Polish

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Drosophila C-terminal Src kinase negatively regulates organ growth and cell proliferation through inhibition of the Src, Jun N-terminal kinase, and STAT pathways, Renee D. Read, Erika A. Bach, and Ross L. Cagan

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Needle-based ablation of renal parenchyma using microwave, cryoablation, impedance- and temperature-based monopolar and bipolar radiofrequency, and liquid and gel chemoablation: Laboratory studies and review of the literature, Jamil Rehman, Jaime Landman, David Lee, Ramakrishna Venkatesh, David G. Bostwick, Chandru Sundaram, and Ralph V. Clayman

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Laparoscopic radical prostatectomy: Washington University initial experience and prospective evaluation of quality of life, Jamil Rehman, Maged M. Ragab, Ramakrishna Venkatesh, Jaime Landman, David Lee, Cathy Chen, Yan Yan, and Chandru P. Sundaram

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Smooth-muscle regeneration after electrosurgical endopyelotomy in a porcine model as confirmed by electron microscopy, Jamil Rehman, Maged M. Ragab, Ramakrishna Venkatesh, Chandru P. Sundaram, S. Ali Khan, Troy Sukkarieh, David Samadi, Bilal Chughtai, Francis White, David Bostwick, and Wayne Waltzer

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The ETT2 gene cluster, encoding a second type III secretion system from Escherichia coli, is present in the majority of strains but has undergone widespread mutational attrition, Chuan-Peng Ren, Roy R. Chaudhuri, Amanda Fivian, Christopher M. Bailey, Martin Antonio, Wayne M. Barnes, and Mark J. Pallen

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Conformational defects slow Golgi exit, block oligomerization, and reduce raft affinity of caveolin-1 mutant proteins, Xiaoyan Ren, Anne G. Ostermeyer, Lynne T. Ramcharan, Youchun Zeng, Douglas M. Lublin, and Deborah A. Brown

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In vitro and in vivo evaluation of a 64Cu-labeled polyethylene glycol-bombesin conjugate, Buck E. Rogers, Debbie Della Manna, and Ahmad Safavy

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Prolongation of life in anephric rats following de novo renal organogenesis, Sharon A. Rogers and Marc R. Hammerman

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Pseudarthrosis of a thirty-nine-year-old dens fracture causing myelopathy, Jonas R. Rudzki, Lawrence G. Lenke, and K. Daniel Riew

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Follow-up results of a phase II study of ibritumomab tiuxetan radioimmunotherapy in patients with relapsed or refractory low-grade, follicular, or transformed B-cell non-Hodgkin's lymphoma and mild thrombocytopenia, Russell Schilder, Arturo Molina, Nancy Bartlett, Thomas Witzig, Leo Gordon, James Murray, Stewart Spies, Hua Wang, Gregory Wiseman, and Christine White

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Clinical and laboratory features of Mycobacterium porcinum, Mark F. Schinsky and et al

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A randomized clinical trial comparing single- and multi-dose combination therapy with diethylcarbamazine and albendazole for treatment of bancroftian filariasis, Maged El Setouhy, Reda M.R. Ramzy, Ehab S. Ahmed, Amr M. Kandil, Omar Hussain, Hoda A. Farid, Hanan Helmy, and Gary J. Weil

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Legionella pneumophila dotU and icmF are required for stability of the Dot/Icm complex, Jessica A. Sexton, Jennifer L. Miller, Aki Yoneda, Thomas E. Kehl-Fie, and Joseph P. Vogel

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The legionella pneumophila PilT homologue DotB exhibits ATPase activity that is critical for intracellular growth, Jessica A. Sexton, Jerome S. Pinkner, Robyn Roth, John E. Heuser, Scott J. Hultgren, and Joseph P. Vogel

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Regulation of hypercompetence in Legionella pneumophila, Jessica A. Sexton and Joseph P. Vogel

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Massive thymic deletion results in systemic autoimmunity through elimination of CD4+ CD25+ T regulatory cells, Fei F. Shih, Laura Mandik-Nayak, Brian T. Wipke, and Paul M. Allen

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Ulnar-sided wrist pain: Diagnosis and treatment, Alexander Y. Shin, Mark A. Deitch, Kavi Sachar, and Martin I. Boyer

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NKG2D recognition and perforin effector function mediate effective cytokine immunotherapy of cancer, Mark J. Smyth, Jeremy Swann, Janice M. Kelly, Erika Cretney, Wayne M. Yokoyama, Andreas Diefenbach, Thomas J. Sayers, and Yoshihiro Hayakawa

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Treatment of terminal peritoneal carcinomatosis by a transducible p53-activating peptide, Eric L. Snyder, Bryan R. Meade, Cheryl C. Saenz, and Steven F. Dowdy

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Identification of a compensatory mutant (lpg2-REV) of Leishmania major able to survive as amastigotes within macrophages without LPG2-dependent glycoconjugates and its significance to virulence and immunization strategies, Gerald F. Spath, Lon-Fye Lye, Hiroaki Segawa, Salvatore J. Turco, and Stephen M. Beverley

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pVHL modification by NEDD8 is required for fibronectin matrix assembly and suppression of tumor development, Natalie H. Stickle, Jacky Chung, Jeffery M. Klco, Richard P. Hill, William G. Kaelin Jr., and Michael Ohh

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Laparoscopic sacrocolpopexy for the correction of vaginal vault prolapse, Chandru P. Sundaram, Ramakrishna Venkatesh, Jaime Landman, and Carl G. Klutke

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Inhibition of aldose reductase by tannoid principles of Emblica officinalis: Implications for the prevention of sugar cataract, P. Suryanarayana, P. Anil Kumar, Megha Saraswat, J. Mark Petrash, and G. Bhanuprakash Reddy

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Motility of urease-deficient derivatives of Helicobacter pylori, Shumin Tan and Douglas E. Berg

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Evaluation of the virological and metabolic effects of switching protease inhibitor combination antiretroviral therapy to nevirapine-based therapy for the treatment of HIV infection, Pablo Tebas, Kevin Yarasheski, Keith Henry, Sherri Claxton, E. Kane, B. Bordenave Regions Hospital, Michael Klebert, and William G. Powderly

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RANKing c-Jun in osteoclast development, Steven L. Teitelbaum

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Gene prediction and verification in a compact genome with numerous small introns, Aaron E. Tenney, Randall H. Brown, Charles Vaske, Jennifer K. Lodge, Tamara L. Doering, and Michael R. Brent

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Substitution of HIV type 1 Nef with HTLV-1 p12, Tomonori Tsukahara and Lee Ratner

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Involvement of salmonella pathogenicity island 2 in the up-regulation of interleukin-10 expression in macrophages: role of protein kinase a signal pathway, Kei-ichi Uchiya, Eduardo A. Groisman, and Toshiaki Nikai

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Regulation of the Ysa type III secretion system of Yersinia enterocolitica by YsaE/SycB and YsrS/YsrR, Kimberly A. Walker and Virginia L. Miller