IL-1β-dependent extravasation of preexisting lung-restricted autoantibodies during lung transplantation activates complement and mediates primary graft dysfunction

Authors

Wenbin Yang, Northwestern University
Daniel Kreisel, Washington University School of Medicine in St. Louis
et al.

Journal

Journal of Clinical Investigation

Publication Date

10-17-2022

Volume

132

Issue

20

First Page

e157975

Document Type

Open Access Publication

DOI

10.1172/JCI157975

Rights and Permissions

Yang W, Cerier EJ, Núñez-Santana FL, Wu Q, Yan Y, Kurihara C, Liu X, Yeldandi A, Khurram N, Avella-Patino D, Sun H, Budinger GRS, Kreisel D, Mohanakumar T, Lecuona E, Bharat A. IL-1β-dependent extravasation of preexisting lung-restricted autoantibodies during lung transplantation activates complement and mediates primary graft dysfunction. J Clin Invest. 2022 Oct 17;132(20):e157975. doi: 10.1172/JCI157975. © 2022, Yang et al. This is an open access article published under the terms of the Creative Commons Attribution 4.0 International License.

Recommended Citation

Yang, Wenbin; Kreisel, Daniel; and et al., "IL-1β-dependent extravasation of preexisting lung-restricted autoantibodies during lung transplantation activates complement and mediates primary graft dysfunction." Journal of Clinical Investigation. 132, 20. e157975 (2022).
https://digitalcommons.wustl.edu/oa_4/593