CRISPR-Cas9 knock-in of T513M and G41S mutations in the murine β-galactosyl-ceramidase gene re-capitulates early-onset and adult-onset forms of Krabbe Disease
Frontiers in Molecular Neuroscience
Open Access Publication
Rights and Permissions
Rebiai R, Rue E, Zaldua S, Nguyen D, Scesa G, Jastrzebski M, Foster R, Wang B, Jiang X, Tai L, Brady ST, van Breemen R, Givogri MI, Sands MS and Bongarzone ER (2022) CRISPR-Cas9 Knock-In of T513M and G41S Mutations in the Murine β–Galactosyl-Ceramidase Gene Re-capitulates Early-Onset and Adult-Onset Forms of Krabbe Disease. Front. Mol. Neurosci. 15:896314. doi: 10.3389/fnmol.2022.896314 © 2022 Rebiai, Rue, Zaldua, Nguyen, Scesa, Jastrzebski, Foster, Wang, Jiang, Tai, Brady, van Breemen, Givogri, Sands and Bongarzone. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
Rebiai, Rima; Rue, Emily; Zaldua, Steve; Nguyen, Duc; Scesa, Giuseppe; Jastrzebski, Martin; Foster, Robert; Wang, Bin; Jiang, Xuntian; Tai, Leon; Brady, Scott T; van Breemen, Richard; Givogri, Maria I; Sands, Mark S; and Bongarzone, Ernesto R, "CRISPR-Cas9 knock-in of T513M and G41S mutations in the murine β-galactosyl-ceramidase gene re-capitulates early-onset and adult-onset forms of Krabbe Disease." Frontiers in Molecular Neuroscience. 15, 896314 (2022).