PGC-1alpha deficiency causes multi-system energy metabolic derangements: Muscle dysfunction, abnormal weight control and hepatic steatosis

Authors

Teresa C. Leone, Washington University School of Medicine in St. LouisFollow
John J. Lehman, Washington University School of Medicine in St. Louis
Brian N. Finck, Washington University School of Medicine in St. LouisFollow
Paul J. Schaeffer, Washington University School of Medicine in St. Louis
Adam R. Wende, Washington University School of Medicine in St. Louis
Sihem Boudina, University of Utah
Michael Courtois, Washington University School of Medicine in St. Louis
David F. Wozniak, Washington University School of Medicine in St. Louis
Nandakumar Sambandam, Washington University School of Medicine in St. Louis
Carlos Bernal-Mizrachi, Washington University School of Medicine in St. LouisFollow
Zhouji Chen, Washington University School of Medicine in St. Louis
John O. Holloszy, Washington University School of Medicine in St. LouisFollow
Denis M. Medeiros, Kansas State University
Robert E. Schmidt, Washington University School of Medicine in St. Louis
Jeffrey E. Saffitz, Washington University School of Medicine in St. Louis
E. D. Abel, University of Utah
Clay F. Semenkovich, Washington University School of Medicine in St. Louis
Daniel P. Kelly, Washington University School of Medicine in St. LouisFollow

Journal

PLoS Biology

Publication Date

2005

Volume

3

Issue

4

Inclusive Pages

672-687

Document Type

Open Access Publication

DOI

10.1371/journal.pbio.0030101

Rights and Permissions

Leone TC, Lehman JJ, Finck BN, Schaeffer PJ, Wende AR, et al. 2005 PGC-1α Deficiency Causes Multi-System Energy Metabolic Derangements: Muscle Dysfunction, Abnormal Weight Control and Hepatic Steatosis. PLoS Biol 3(4): e101. doi:10.1371/journal.pbio.0030101

Recommended Citation

Leone, Teresa C.; Lehman, John J.; Finck, Brian N.; Schaeffer, Paul J.; Wende, Adam R.; Boudina, Sihem; Courtois, Michael; Wozniak, David F.; Sambandam, Nandakumar; Bernal-Mizrachi, Carlos; Chen, Zhouji; Holloszy, John O.; Medeiros, Denis M.; Schmidt, Robert E.; Saffitz, Jeffrey E.; Abel, E. D.; Semenkovich, Clay F.; and Kelly, Daniel P., "PGC-1alpha deficiency causes multi-system energy metabolic derangements: Muscle dysfunction, abnormal weight control and hepatic steatosis." PLoS Biology. 3, 4. 672-687. (2005).
https://digitalcommons.wustl.edu/open_access_pubs/379