Open Access Publication
Haspel, Jeffrey A. and et al, ,"Circadian rhythm reprogramming during lung inflammation." Nature Communications.5,. 4753. (2014).
Supplementary Figures 1-12, Supplementary Tables 1-4 and Supplementary References
ncomms5753-s2.xlsx (532 kB)
The normal lung circadian trancriptome.
ncomms5753-s3.xlsx (16 kB)
KEGG functional annotation enrichment analysis of the basal lung circadian transcriptome.
ncomms5753-s4.xlsx (12 kB)
KEGG functional annotation enrichment analysis of the basal lung circadian transcriptome excluding leukocyte associated genes.
ncomms5753-s5.xlsx (13 kB)
Rhythm analysis of clock pathway gene expression in the basal state and during endotoxemia.
ncomms5753-s6.xlsx (1957 kB)
The LPS-specific lung circadian trancriptom
ncomms5753-s7.xlsx (15 kB)
Functional annotation analysis of genes that are rhythmic solely during endotoxemia (Period 15-36 hrs only).
ncomms5753-s8.xlsx (13 kB)
Functional annotation analysis of uniquely rhythmically expressed genes during endotoxemia with leukocyte associated genes excluded (period 15-36 hrs only).
ncomms5753-s9.xlsx (13 kB)
Summary of rhythm analysis for immunohistochemical data presented in Fig. 5.
ncomms5753-s10.xlsx (30 kB)
Metabolites exhibiting rhythmic variation in the basal lung.
ncomms5753-s11.xlsx (47 kB)
Lung metabolites exhibiting rhythmic variation during endotoxemia.
ncomms5753-s12.xlsx (10 kB)
COSOPT rhythm analysis of data depicted graphically in Fig. 8.
ncomms5753-s13.xlsx (12 kB)
IMPaLA functional annotation analysis for terms that are jointly enriched among rhythmic genes and metabolites.
ncomms5753-s14.xlsx (15 kB)
Rhythm analysis of MPO morphometry presented in Fig. 10e.
ncomms5753-s15.xlsx (11 kB)
Normalized microarray Log2MFI expression data obtained from Microarray Experiment #1.
ncomms5753-s16.xlsx (26732 kB)
Normalized microarray Log2MFI expression data obtained from Microarray Experiment #2 (basal state).
ncomms5753-s17.xlsx (21561 kB)
Normalized microarray Log2MFI expression data obtained from Microarray Experiment #2 (endotoxemia).
ncomms5753-s18.xlsx (16372 kB)
List of Leukocyte Associated Genes Used for Informatic Analysis.
ncomms5753-s19.xlsx (48 kB)