Open Access Publication
Frazier, Thomas; Youngstrom, Eric A.; Hardan, Antonio Y.; Georgiades, Stelios; Constantino, John N.; and Eng, Charis, ,"Quantitative autism symptom patterns recapitulate differential mechanisms of genetic transmission in single and multiple incidence families." Molecular Autism.6,. 58. (2015).
Social Communication Questionnaire (SCQ) and Social Responsiveness Scale (SRS) item mapping to DSM-5 criteria.
s13229-015-0050-z-s2.docx (14 kB)
Main effect and interaction tests examining SRS total raw score by family incidence type and diagnostic status.
s13229-015-0050-z-s3.docx (298 kB)
Frequency distributions of SRS total raw scores in non-ASD and ASD-affected children from single and multiple incidence families, separately for female and male children.
s13229-015-0050-z-s4.docx (23 kB)
Autism symptom levels ( M + 95 % CI) in non-ASD siblings (male and female siblings combined) from female ASD-containing and male-only families, separately for single and multiple incidence families.
s13229-015-0050-z-s5.docx (14 kB)
Main effect and interaction tests examining SRS total raw score by family incidence type and family sex type in non-ASD siblings.
s13229-015-0050-z-s6.docx (13 kB)
Main effects examining SRS total raw score by family incidence type and family sex type in ASD-affected siblings.
s13229-015-0050-z-s7.docx (14 kB)
Recurrence risk of ASD in next-born siblings by sex of the sibling and family sex type.