DOI

10.1038/ncomms11853

Document Type

Open Access Publication

Journal

Nature Communications

Volume

7

Inclusive Pages

11853

Publication Date

2016

ncomms11853-s3.pdf (3853 kB)
Supplementary Figures 1-21, Supplementary Tables 1-6 and Supplementary References

ncomms11853-s1.avi (61442 kB)
Endothelial lineage-derived Yfp+ cells undergo EndMT and give rise to Fap+ fibroblast-like cells within intimal plaques. Immunofluorescence confocal microscopy with z-stack acquisition of a thoracic aortic section from a tamoxifen-induced end. SclCreERT;R26RstopYfp;ApoE-/- mice fed with 30 weeks of HFD revealed intimal plaque Yfp+ cells co-expressing the fibroblast marker Fap. Movie corresponds to the same section as displayed in Fig. 2c.

ncomms11853-s2.avi (61442 kB)

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