7‑hydroxymitragynine is an active metabolite of mitragynine and a key mediator of its analgesic effects

Authors

Andrew C. Kruegel, Columbia University
Rajendra Uprety, Memorial Sloan Kettering Cancer Center
Steven G. Grinnell, Columbia University
Cory Langreck, Columbia University
Elizabeth A. Pekarskaya, Columbia University
Valerie Le Rouzic, Memorial Sloan Kettering Cancer Center
Michael Ansonoff, Rutgers Robert Wood Johnson Medical School
Madalee M. Gassaway, Columbia University
John E. Pintar, Rutgers Robert Wood Johnson Medical School
Gavril W. Pasternak, Memorial Sloan Kettering Cancer Center
Jonathan A. Javitch, Columbia University
Susruta Majumdar, Washington University School of Medicine in St. Louis
Dalibor Sames, Columbia University

Journal

ACS Central Science

Publication Date

2019

Volume

5

Issue

6

Inclusive Pages

992-1001

Document Type

Open Access Publication

DOI

10.1021/acscentsci.9b00141

Rights and Permissions

Kruegel, A. C., Uprety, R., Grinnell, S. G., Langreck, C., Pekarskaya, E. A., Le Rouzic, V., . . . Sames, D. (2019). 7-Hydroxymitragynine Is an Active Metabolite of Mitragynine and a Key Mediator of Its Analgesic Effects. Acs Central Science, 5(6), 992-1001. doi:10.1021/acscentsci.9b00141 This is an open access article published under an ACS AuthorChoice License, which permits copying and redistribution of the article or any adaptations for non-commercial purposes.

Recommended Citation

Kruegel, Andrew C.; Uprety, Rajendra; Grinnell, Steven G.; Langreck, Cory; Pekarskaya, Elizabeth A.; Le Rouzic, Valerie; Ansonoff, Michael; Gassaway, Madalee M.; Pintar, John E.; Pasternak, Gavril W.; Javitch, Jonathan A.; Majumdar, Susruta; and Sames, Dalibor, "7‑hydroxymitragynine is an active metabolite of mitragynine and a key mediator of its analgesic effects." ACS Central Science. 5, 6. 992-1001. (2019).
https://digitalcommons.wustl.edu/open_access_pubs/7953