Journal
Brain pathology
Publication Date
11-1-2018
Volume
28
Issue
6
First Page
806
Last Page
821
Document Type
Open Access Publication
DOI
10.1111/bpa.12626
Rights and Permissions
Kothari, P. H., Kolar, G. R., Jen, J. C., Hajj‐Ali, R. , Bertram, P. , Schmidt, R. E. and Atkinson, J. P. (2018), TREX1 is expressed by microglia in normal human brain and increases in regions affected by ischemia. Brain Pathology, 28: 806-821. doi:10.1111/bpa.12626 © 2018 The Authors Brain Pathology published by John Wiley & Sons Ltd on behalf of International Society of Neuropathology This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Recommended Citation
Kothari, Parul H; Kolar, Grant R; Jen, Joanna C; Hajj-Ali, Rula; Bertram, Paula; Schmidt, Robert E; and Atkinson, John P, "TREX1 is expressed by microglia in normal human brain and increases in regions affected by ischemia." Brain pathology. 28, 6. 806 - 821. (2018).
https://digitalcommons.wustl.edu/open_access_pubs/8192
Figure S1. Expression of TREX1 protein isoforms and transcript variants
bpa12626-sup-0002-figs2.tiff (783 kB)
Figure S2. TREX1 expressing cells are not astrocytes.
bpa12626-sup-0003-figs3.tif (933 kB)
Figure S3. Absolute cell counts for Iba1 and TREX1 by brain region in normal controls and cases of RVCL and ischemic stroke.
bpa12626-sup-0004-figs4.tiff (2034 kB)
Figure S4. Representative immunohistochemical staining for TREX1 (brown) in normal controls (left panel) and undamaged tissue in RVCL cases (right panel) in specified brain regions.
bpa12626-sup-0005-figs5.tif (1540 kB)
Figure S5. TREX1 cells are ameboid microglia or infiltrating peripheral macrophages along the edges of ischemic lesions.
bpa12626-sup-0006-tables1.docx (71 kB)
Table S1. Summary of the tissue sections analyzed.
