Phase 1 dose escalation study of the allosteric AKT inhibitor BAY 1125976 in advanced solid cancer-Lack of association between activating AKT mutation and AKT inhibition-derived efficacy
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Schneeweiss A, Hess D, Joerger M, Varga A, Moulder S, Tsimberidou AM, Ma C, Hurvitz SA, Rentzsch C, Rudolph M, Thiele S, Boix O, Wilkinson G, Lagkadinou E, Ocker M. Phase 1 Dose Escalation Study of the Allosteric AKT Inhibitor BAY 1125976 in Advanced Solid Cancer—Lack of Association between Activating AKT Mutation and AKT Inhibition-Derived Efficacy. Cancers. 2019; 11(12):1987. doi: 10.3390/cancers11121987.
Schneeweiss, Andreas; Hess, Dagmar; Joerger, Markus; Varga, Andrea; Moulder, Stacy; Tsimberidou, Apostolia M; Ma, Cynthia; Hurvitz, Sara A; Rentzsch, Christine; Rudolph, Marion; Thiele, Silke; Boix, Oliver; Wilkinson, Gary; Lagkadinou, Eleni; and Ocker, Matthias, "Phase 1 dose escalation study of the allosteric AKT inhibitor BAY 1125976 in advanced solid cancer-Lack of association between activating AKT mutation and AKT inhibition-derived efficacy." Cancers (Basel). 11, 12. 1987 (2019).