Remethylation of Dnmt3a−/− hematopoietic cells is associated with partial correction of gene dysregulation and reduced myeloid skewing

Authors

Shamika Ketkar, Washington University School of Medicine in St. Louis
Angela M. Verdoni, Washington University School of Medicine in St. Louis
Amanda M. Smith, Washington University School of Medicine in St. Louis
Celia V. Bangert, Washington University School of Medicine in St. Louis
Elizabeth R. Leight, Washington University School of Medicine in St. Louis
David Y. Chen, Washington University School of Medicine in St. Louis
Meryl K. Brune, Washington University School of Medicine in St. Louis
Nichole M. Helton, Washington University School of Medicine in St. Louis
Mieke Hoock, Washington University School of Medicine in St. Louis
Daniel R. George, Washington University School of Medicine in St. Louis
Catrina Fronick, Washington University School of Medicine in St. Louis
Robert S. Fulton, Washington University School of Medicine in St. Louis
Sai Mukund Ramakrishnan, Washington University School of Medicine in St. Louis
Gue Su Chang, Washington University School of Medicine in St. Louis
Allegra A. Petti, Washington University School of Medicine in St. Louis
David H. Spencer, Washington University School of Medicine in St. Louis
Christopher A. Miller, Washington University School of Medicine in St. Louis
Timothy J. Ley, Washington University School of Medicine in St. Louis

Journal

Proceedings of the National Academy of Sciences of the United States of America

Publication Date

2020

Volume

117

Issue

6

First Page

3123

Last Page

3134

Document Type

Open Access Publication

DOI

10.1073/pnas.1918611117

Rights and Permissions

Ketkar, S., Verdoni, A. M., Smith, A. M., Bangert, C. V., Leight, E. R., Chen, D. Y., . . . Ley, T. J. (2020). Remethylation of Dnmt3a−/− hematopoietic cells is associated with partial correction of gene dysregulation and reduced myeloid skewing. Proceedings of the National Academy of Sciences of the United States of America, 117(6), 3123-3134. doi:10.1073/pnas.1918611117 This open access article is distributed under Creative Commons Attribution-NonCommercialNoDerivatives License 4.0 (CC BY-NC-ND).

Recommended Citation

Ketkar, Shamika; Verdoni, Angela M.; Smith, Amanda M.; Bangert, Celia V.; Leight, Elizabeth R.; Chen, David Y.; Brune, Meryl K.; Helton, Nichole M.; Hoock, Mieke; George, Daniel R.; Fronick, Catrina; Fulton, Robert S.; Ramakrishnan, Sai Mukund; Chang, Gue Su; Petti, Allegra A.; Spencer, David H.; Miller, Christopher A.; and Ley, Timothy J., "Remethylation of Dnmt3a−/− hematopoietic cells is associated with partial correction of gene dysregulation and reduced myeloid skewing." Proceedings of the National Academy of Sciences of the United States of America. 117, 6. 3123 - 3134. (2020).
https://digitalcommons.wustl.edu/open_access_pubs/8869