The Journal of Experimental Medicine
Open Access Publication
Barthélemy, Nicolas R.; Horie, Kanta; Sato, Chihiro; and Bateman, Randall J., ,"Blood plasma phosphorylated-tau isoforms track CNS change in Alzheimer's disease." The Journal of Experimental Medicine.,. . (2020).
shows replication in non-spiked plasma pool from healthy volunteers and method performance measured in the spike and recovery experiment.
jem_20200861_tables2.docx (27 kB)
shows peptides sequences and corresponding MS/MS transitions used for the quantitation of plasma tau peptides.
jem_20200861_tables3.docx (25 kB)
shows AUC comparison by DeLong test on p-tau217 and p-tau181 performance in separating amyloid positive from amyloid negative.
Available for download on Saturday, March 13, 2021