Spatial origins of compound action potential responses to varying stimulation rates, frequencies, and levels were investigated. A technique to measure the regions in the cochlea generating each response in which a neurotoxic drug (kainic acid) is slowly injected into the cochlear apex was used. This induces a progressive ablation of responses from apex (low frequency) to base (high frequency), allowing the spatial origins of cochlear responses to be quantified.
Program in Audiology and Communication Sciences, Washington University School of Medicine
Action Potentials; Cochlea; Ear, Inner
Donovan, Kathryn Marie, "Changes of cochlear function during cochlear fluids manipulations" (2015). Independent Studies and Capstones. Paper 716. Program in Audiology and Communication Sciences, Washington University School of Medicine.