Breast cancer derived GM-CSF regulates arginase 1 in myeloid cells to promote an immunosuppressive microenvironment

Authors

• Xinming Su, Washington University School of Medicine in St. Louis
• Yalin Xu, Washington University School of Medicine in St. Louis
• Gregory C Fox, Washington University School of Medicine in St. Louis
• Jingyu Xiang, Washington University School of Medicine in St. Louis
• Kristin A Kwakwa, Washington University School of Medicine in St. Louis
• Jennifer L Davis, Washington University School of Medicine in St. Louis
• Jad I Belle, Washington University School of Medicine in St. Louis
• Wen-Chih Lee, Washington University School of Medicine in St. Louis
• Wing H Wong, Washington University School of Medicine in St. Louis
• Francesca Fontana, Washington University School of Medicine in St. Louis
• Leonel Hernandez-Aya, Washington University School of Medicine in St. Louis
• Takayuki Kobayashi, Washington University School of Medicine in St. Louis
• Helen M Tomasson, Washington University School of Medicine in St. Louis
• Junyi Su, Washington University School of Medicine in St. Louis
• Suzanne J Bakewell, Washington University School of Medicine in St. Louis
• Sheila A Stewart, Washington University School of Medicine in St. Louis
• Christopher Egbulefu, Washington University School of Medicine in St. Louis
• Partha Karmakar, Washington University School of Medicine in St. Louis
• Melissa A Meyer, Washington University School of Medicine in St. Louis
• Deborah J Veis, Washington University School of Medicine in St. Louis
• David G DeNardo, Washington University School of Medicine in St. Louis
• Gregory M Lanza, Washington University School of Medicine in St. Louis
• Samuel Achilefu, Washington University School of Medicine in St. Louis
• Katherine N Weilbaecher, Washington University School of Medicine in St. Louis

Journal

The Journal of Clinical Investigation

Publication Date

2021

Document Type

Open Access Publication

DOI

10.1172/JCI145296

Rights and Permissions

Su X, Xu Y, Fox GC, et al. Breast cancer derived GM-CSF regulates arginase 1 in myeloid cells to promote an immunosuppressive microenvironment [published online ahead of print, 2021 Sep 14]. J Clin Invest. 2021;145296. doi:10.1172/JCI145296.

Recommended Citation

Su, Xinming; Xu, Yalin; Fox, Gregory C; Xiang, Jingyu; Kwakwa, Kristin A; Davis, Jennifer L; Belle, Jad I; Lee, Wen-Chih; Wong, Wing H; Fontana, Francesca; Hernandez-Aya, Leonel; Kobayashi, Takayuki; Tomasson, Helen M; Su, Junyi; Bakewell, Suzanne J; Stewart, Sheila A; Egbulefu, Christopher; Karmakar, Partha; Meyer, Melissa A; Veis, Deborah J; DeNardo, David G; Lanza, Gregory M; Achilefu, Samuel; and Weilbaecher, Katherine N, "Breast cancer derived GM-CSF regulates arginase 1 in myeloid cells to promote an immunosuppressive microenvironment." The Journal of Clinical Investigation. (2021).
https://digitalcommons.wustl.edu/open_access_pubs/10918