Open Access Publication
Jones, Lynne and et al, "Brain microvasculature defects and Glut1 deficiency syndrome averted by early repletion of the glucose transporter-1 protein." Nature Communications. 8, (2017).
Peer Review File.pdf (1386 kB)
Supplementary Movie 1.avi (6074 kB)
(WT) - Compilation of images, using 2-photon microscopy, of the cerebral capillaries in a WT mouse.
Supplementary Movie 2.avi (6390 kB)
(Mut + AAV-Glut1) - Compilation of images, using 2-photon microscopy, of cerebral capillaries in a Glut1 DS mouse restored for the Glut1 protein showing normalization of the extent of the microvasculature.
Supplementary Movie 3.avi (3604 kB)
(Mut + Vehicle) - Compilation of images, using 2-phton microscopy, of the brain capillaries of a Glut1 DS mouse treated with vehicle showing diminution of the microvasculature.