Hair cell death and regeneration on the three distal-most neuromasts in the posterior lateral line of zebrafish larvae were investigated after neomycin treatment. Treatment with ibuprofen, dexamethasone and salicylate examined the role of a normal inflammatory response on hair cell regeneration. Regeneration was observed 48 hours post-treatment indicating these reagents have no effect on the regeneration process.
Program in Audiology and Communication Sciences, Washington University School of Medicine
Anti-Inflammatory Agents; Regeneration
Garbo, Sarah C., "The effect of anti-inflammatory drugs on hair cell regeneration in the zebrafish lateral line" (2014). Independent Studies and Capstones. Paper 694. Program in Audiology and Communication Sciences, Washington University School of Medicine.