Searching the druggable genome using large language models

Authors

• Lars Schimmelpfennig, Washington University School of Medicine in St. Louis
• Matthew Cannon, Nationwide Children's Hospital
• Quentin Cody, Independent Researcher
• Joshua McMichael, Washington University School of Medicine in St. Louis
• Adam C Coffman, Washington University School of Medicine in St. Louis
• Susanna Kiwala, Washington University School of Medicine in St. Louis
• Kilannin Krysiak, Washington University School of Medicine in St. Louis
• Alex H Wagner, The Ohio State University
• Malachi Griffith, Washington University School of Medicine in St. Louis
• Obi L Griffith, Washington University School of Medicine in St. Louis

Journal

Bioinformatics

Publication Date

8-31-2026

Volume

42

Issue

9

First Page

btag632

Document Type

Open Access Publication

DOI

10.1093/bioinformatics/btag632

Rights and Permissions

Lars Schimmelpfennig, Matthew Cannon, Quentin Cody, Joshua McMichael, Adam C Coffman, Susanna Kiwala, Kilannin Krysiak, Alex H Wagner, Malachi Griffith, Obi L Griffith, Searching the druggable genome using large language models, Bioinformatics, Volume 42, Issue 9, September 2026, btag632, https://doi.org/10.1093/bioinformatics/btag632. https://academic.oup.com/bioinformatics/article/42/9/btag632/8768654?login=true. © The Author(s) 2026. Published by Oxford University Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

Recommended Citation

Schimmelpfennig, Lars; Cannon, Matthew; Cody, Quentin; McMichael, Joshua; Coffman, Adam C; Kiwala, Susanna; Krysiak, Kilannin; Wagner, Alex H; Griffith, Malachi; and Griffith, Obi L, "Searching the druggable genome using large language models." Bioinformatics. 42, 9. btag632 (2026).
https://digitalcommons.wustl.edu/oa_4/7426

Department

ICTS (Institute of Clinical and Translational Sciences)

Additional Links

Supplemental material is available for this article at publisher site.