Phytic acid (InsP6) activates HDAC3 epigenetic axis to maintain intestinal barrier function

Authors

• Sujan Chatterjee, University of Nevada, Las Vegas
• Katherine Huang, Washington University School of Medicine in St. Louis
• Kayci Huff-Hardy, Washington University School of Medicine in St. Louis
• Richard Rood, Washington University School of Medicine in St. Louis
• Anas Gremida, Washington University School of Medicine in St. Louis
• Martin Gregory, Washington University School of Medicine in St. Louis
• Chien-Huan Chen, Washington University School of Medicine in St. Louis
• Parakkal Deepak, Washington University School of Medicine in St. Louis
• et al.

Journal

Nature Communications

Publication Date

2-9-2026

Volume

17

Issue

1

First Page

4770

Document Type

Open Access Publication

DOI

10.1038/s41467-026-68994-0

Rights and Permissions

Chatterjee, S., Sin, Z., Tran, N. et al. Phytic acid (InsP6) activates HDAC3 epigenetic axis to maintain intestinal barrier function. Nat Commun 17, 4770 (2026). https://doi.org/10.1038/s41467-026-68994-0 This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.

Recommended Citation

Chatterjee, Sujan; Huang, Katherine; Huff-Hardy, Kayci; Rood, Richard; Gremida, Anas; Gregory, Martin; Chen, Chien-Huan; Deepak, Parakkal; and et al., "Phytic acid (InsP6) activates HDAC3 epigenetic axis to maintain intestinal barrier function." Nature Communications. 17, 1. 4770 (2026).
https://digitalcommons.wustl.edu/oa_4/7510

Department

ICTS (Institute of Clinical and Translational Sciences)

Additional Links

Supplemental material is available for this article at publisher site.