Diurnal rhythm in chimeric antigen receptor T cell effectiveness in an observational study of 715 patients

Authors

• Patrick G. Lyons, Oregon Health & Science University
• Emily Gill, Washington University School of Medicine in St. Louis
• Prisha Kumar, Washington University School of Medicine in St. Louis
• Melissa Beasley, Washington University School of Medicine in St. Louis
• Brenna Park-Egan, Oregon Health & Science University
• Zulfiqar A. Lokhandwala, Oregon Health & Science University
• Katie M. Lebold, Oregon Health & Science University
• Brandon Hayes-Lattin, Oregon Health & Science University
• Catherine L. Hough, Oregon Health & Science University
• Nathan Singh, Washington University School of Medicine in St. Louis
• Guy Hazan, Ben Gurion University
• Huram Mok, Washington University School of Medicine in St. Louis
• Janice M. Huss, Washington University School of Medicine in St. Louis
• Colleen A. McEvoy, Washington University School of Medicine in St. Louis
• Jeffrey A. Haspel, Washington University School of Medicine in St. Louis

Journal

JCI Insight

Publication Date

2-9-2026

Volume

11

Issue

3

First Page

e201159

Document Type

Open Access Publication

DOI

10.1172/jci.insight.201159

Rights and Permissions

Lyons PG, Gill E, Kumar P, Beasley M, Park-Egan B, Lokhandwala ZA, Lebold KM, Hayes-Lattin B, Hough CL, Singh N, Hazan G, Mok H, Huss JM, McEvoy CA, Haspel JA. Diurnal rhythm in chimeric antigen receptor T cell effectiveness in an observational study of 715 patients. JCI Insight. 2025 Dec 18;11(3):e201159. doi: 10.1172/jci.insight.201159. © 2025, Lyons et al. This is an open access article published under the terms of the Creative Commons Attribution 4.0 International License.

Recommended Citation

Lyons, Patrick G.; Gill, Emily; Kumar, Prisha; Beasley, Melissa; Park-Egan, Brenna; Lokhandwala, Zulfiqar A.; Lebold, Katie M.; Hayes-Lattin, Brandon; Hough, Catherine L.; Singh, Nathan; Hazan, Guy; Mok, Huram; Huss, Janice M.; McEvoy, Colleen A.; and Haspel, Jeffrey A., "Diurnal rhythm in chimeric antigen receptor T cell effectiveness in an observational study of 715 patients." JCI Insight. 11, 3. e201159 (2026).
https://digitalcommons.wustl.edu/oa_4/7690

Department

ICTS (Institute of Clinical and Translational Sciences)

Additional Links

Supplemental material is available for this article at publisher site.