Title

Tumor-derived Interleukin-1α and Leukemia Inhibitory Factor promote extramedullary hematopoiesis

Author(s)

Derek A.G. Barisas, Washington University School of Medicine in St. Louis
Seonyoung Kim, Washington University School of Medicine in St. Louis
Ashraf Ul Kabir, Washington University School of Medicine in St. Louis
Jun Wu, Washington University School of Medicine in St. Louis
Karen Krchma, Washington University School of Medicine in St. Louis
Minseo Kim, Washington University School of Medicine in St. Louis
Madhav Subramanian, Washington University School of Medicine in St. Louis
Bernd H. Zinselmeyer, Washington University School of Medicine in St. Louis
Colin L. Stewart, A*STAR Skin Research Laboratories (Singapore)
Kyunghee Choi, Washington University School of Medicine in St. Louis

Orcid ID

Derek Barisas (0000-0003-0707-2659) (orcid.org)

Seonyoung Kim (0000-0002-8854-287X) (orcid.org)

Ashraf Kabir (0000-0002-9449-8238) (orcid.org)

Jun Wu (0000-0002-1891-368X) (orcid.org)

Karen Krchma (0000-0003-0800-8456) (orcid.org)

Minseo Kim (0000-0003-0253-0921) (orcid.org)

Madhav Subramanian (0000-0002-1957-4982) (orcid.org)

Bernd Zinselmeyer (0000-0003-4172-6767) (orcid.org)

Colin L Stewart (0000-0002-4988-536X) (orcid.org)

Kyunghee Choi (0000-0002-9634-9375) (orcid.org) corresponding author

Resource Type

Dataset

DOI

https://doi.org/10.48765/8qwk-k125

Funding

NIH T32 AI007163 (to D.A.G.B), N.I.H. R37AI049653 (to B.H.Z.), N.I.H. R01HL149954 (to K.C.), N.I.H. R01HL55337(to K.C.), and by the Foundation for Barnes-Jewish Hospital, Grant Number: 5130 (Siteman Investment Program Research Development Awards to K.C.)

Description

This dataset contains raw data supporting all figures and supplemental figures, except for single cell RNA sequencing data and serum cytokine profiling data, used in PLOS Biology paper, Tumor-derived interleukin-1α and leukemia inhibitory factor promote extramedullary hematopoiesis (DOI: https://doi.org/10.1371/journal.pbio.3001746). This dataset includes 31 folders organized by Figure number and description of data type (flow cytometry, RT qPCR, ELISA, Immunofluorescence) and each folder contains a data dictionary file to describe variables.

Keywords

Extramedullary Hematopoiesis, Spleen, Hematopoietic Stem Cells, Hematopoiesis, Hematopoietic System, Interleukin-1alpha, OSM-LIF Receptors, Leukemia Inhibitory Factor, Breast Neoplasms, Carcinoma

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Publication Date

6-12-2023

Related Content

Flow Repository accession numbers FR-FCM-Z626, FR-FCM-Z627, and FR-FCM-Z628, GEO accession number GSE207940

Associated Publication

• https://doi.org/10.1371/journal.pbio.3001746

Recommended Citation

Barisas, Derek A.G.; Kim, Seonyoung; Kabir, Ashraf Ul; Wu, Jun; Krchma, Karen; Kim, Minseo; Subramanian, Madhav; Zinselmeyer, Bernd H.; Stewart, Colin L.; and Choi, Kyunghee, "Tumor-derived Interleukin-1α and Leukemia Inhibitory Factor promote extramedullary hematopoiesis" (2023). Data and Supporting Files. Paper 8.
https://digitalcommons.wustl.edu/data/8