Directed mutational scanning reveals a balance between acidic and hydrophobic residues in strong human activation domains

Authors

Max V Staller, Washington University School of Medicine in St. Louis
Eddie Ramirez, Washington University School of Medicine in St. Louis
Sanjana R Kotha, University of California - Berkeley
Alex S Holehouse, Washington University School of Medicine in St. Louis
Rohit V Pappu, Washington University School of Medicine in St. Louis
Barak A Cohen, Washington University School of Medicine in St. Louis

Journal

Cell Systems

Publication Date

4-20-2022

Volume

13

Issue

4

First Page

334

Last Page

345.e5

Document Type

Open Access Publication

DOI

10.1016/j.cels.2022.01.002

Rights and Permissions

Staller MV, Ramirez E, Kotha SR, Holehouse AS, Pappu RV, Cohen BA. Directed mutational scanning reveals a balance between acidic and hydrophobic residues in strong human activation domains. Cell Syst. 2022 Apr 20;13(4):334-345.e5. doi: 10.1016/j.cels.2022.01.002. Copyright 2022 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)

Recommended Citation

Staller, Max V; Ramirez, Eddie; Kotha, Sanjana R; Holehouse, Alex S; Pappu, Rohit V; and Cohen, Barak A, "Directed mutational scanning reveals a balance between acidic and hydrophobic residues in strong human activation domains." Cell Systems. 13, 4. 334 - 345.e5. (2022).
https://digitalcommons.wustl.edu/oa_4/1401

Department

ICTS (Institute of Clinical and Translational Sciences)

Additional Links

Supplemental material is available for this article at publisher site.