Zika virus oncolytic activity requires CD8+ T cells and is boosted by immune checkpoint blockade

Authors

Sharmila Nair, Washington University School of Medicine in St. Louis
Luciano Mazzoccoli, Washington University School of Medicine in St. Louis
Arijita Jash, Washington University School of Medicine in St. Louis
Jennifer Govero, Washington University School of Medicine in St. Louis
Sachendra S Bais, Washington University School of Medicine in St. Louis
Tong Hu, Washington University School of Medicine in St. Louis
Camila R Fontes-Garfias, University of Texas Medical Branch
Chao Shan, University of Texas Medical Branch
Hideho Okada, University of California, San Francisco
Sujan Shresta, La Jolla Institute for Immunology
Jeremy N Rich, University of California - San Diego
Pei-Yong Shi, University of Texas Medical Branch
Michael S Diamond, Washington University School of Medicine in St. Louis
Milan G Chheda, Washington University School of Medicine in St. Louis

Journal

JCI Insight

Publication Date

1-11-2021

Volume

6

Issue

1

First Page

e144619

Document Type

Open Access Publication

DOI

10.1172/jci.insight.144619

Rights and Permissions

Nair S, Mazzoccoli L, Jash A, Govero J, Bais SS, Hu T, Fontes-Garfias CR, Shan C, Okada H, Shresta S, Rich JN, Shi PY, Diamond MS, Chheda MG. Zika virus oncolytic activity requires CD8+ T cells and is boosted by immune checkpoint blockade. JCI Insight. 2021 Jan 11;6(1):e144619. doi: 10.1172/jci.insight.144619. PMID: 33232299; PMCID: PMC7821591. © 2021, Nair et al. This is an open access article published under the terms of the Creative Commons Attribution 4.0 International License.

Recommended Citation

Nair, Sharmila; Mazzoccoli, Luciano; Jash, Arijita; Govero, Jennifer; Bais, Sachendra S; Hu, Tong; Fontes-Garfias, Camila R; Shan, Chao; Okada, Hideho; Shresta, Sujan; Rich, Jeremy N; Shi, Pei-Yong; Diamond, Michael S; and Chheda, Milan G, "Zika virus oncolytic activity requires CD8+ T cells and is boosted by immune checkpoint blockade." JCI Insight. 6, 1. e144619 (2021).
https://digitalcommons.wustl.edu/open_access_pubs/10069