A synthetic mechanogenetic gene circuit for autonomous drug delivery in engineered tissues

Authors

Robert J Nims, Washington University School of Medicine in St. Louis
Lara Pferdehirt, Washington University School of Medicine in St. Louis
Noelani B Ho, Duke University
Alireza Savadipour, Washington University School of Medicine in St. Louis
Jeremiah Lorentz, Washington University School of Medicine in St. Louis
Sima Sohi, Washington University in St. Louis
Jordan Kassab, Washington University in St. Louis
Alison K Ross, Washington University School of Medicine in St. Louis
Christopher J O'Conor, Washington University School of Medicine in St. Louis
Wolfgang B Liedtke, Duke University
Bo Zhang, Washington University School of Medicine in St. Louis
Amy L McNulty, Duke University
Farshid Guilak, Washington University School of Medicine in St. Louis

Journal

Science Advances

Publication Date

2021

Volume

7

Issue

5

Document Type

Open Access Publication

DOI

10.1126/sciadv.abd9858

Rights and Permissions

Nims RJ, Pferdehirt L, Ho NB, et al. A synthetic mechanogenetic gene circuit for autonomous drug delivery in engineered tissues. Sci Adv. 2021;7(5):eabd9858. Published 2021 Jan 27. doi:10.1126/sciadv.abd9858. Copyright © 2021 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).

Recommended Citation

Nims, Robert J; Pferdehirt, Lara; Ho, Noelani B; Savadipour, Alireza; Lorentz, Jeremiah; Sohi, Sima; Kassab, Jordan; Ross, Alison K; O'Conor, Christopher J; Liedtke, Wolfgang B; Zhang, Bo; McNulty, Amy L; and Guilak, Farshid, "A synthetic mechanogenetic gene circuit for autonomous drug delivery in engineered tissues." Science Advances. 7, 5. (2021).
https://digitalcommons.wustl.edu/open_access_pubs/10157