Journal

Elife

Publication Date

2021

Volume

10

First Page

e68457

Document Type

Open Access Publication

DOI

10.7554/eLife.68457

elife-68457-fig1-data1-v1.xlsx (10 kB)
Figure 1—source data 1 Source files for scRNAseq analysis; top DEG for cell clustering and cluster counts.

elife-68457-fig1-data2-v1.xlsx (929 kB)
Figure 1—source data 2 Significant ligand-receptor interactions (p-value < 0.05).

elife-68457-fig2-data1-v1.xlsx (88658 kB)
Figure 2—source data 1 Source files for scRNAseq analysis; DEG in endothelial cells, pericytes and Schwann cells in response to peripheral and central injuries (FDR ≤ 0.05, fold-change ≥ 2), repair Schwann cell genes expression across injuries.

elife-68457-fig3-data1-v1.xlsx (50222 kB)
Figure 3—source data 1 Source files for scRNAseq analysis; Macrophage markers in the macrophage cluster, DEG in macrophages (FDR ≤ 0.05, fold-change ≥ 2) and MkKi67 expression.

elife-68457-fig4-data1-v1.xlsx (588 kB)
Figure 4—source data 1 Source files for scRNAseq analysis, flow cytometry additional experiments.

elife-68457-fig5-data1-v1.xlsx (35 kB)
Figure 5—source data 1 Source files for scRNAseq analysis; SGC marker genes expression, DEG in SGC subclusters (FDR ≤ 0.05, fold-change ≥2), Astrocytes and Schwann cells.

elife-68457-fig6-data1-v1.xlsx (794 kB)
Figure 6—source data 1 Source files for scRNAseq analysis; SGC subtypes injury marker genes, DEG in SGC subclusters in all injuries (FDR ≤ 0.05, fold-change ≥2), cluster distribution.

elife-68457-fig7-data1-v1.xlsx (50742 kB)
Figure 7—source data 1 Source files for scRNAseq analysis; DEG in SGC (FDR ≤ 0.05, fold-change ≥ 2), PPARαexpression in all cell types. Image analysis for axon regeneration.

elife-68457-sa2-fig1-v1.jpg (55 kB)
Enriched pathway (KEGG 2019) in SGC 3 days after SNC in our previous data set (2020) and new data set (2021).

elife-68457-video1.mp4 (9607 kB)
3D video of Imoonglia Glia.

elife-68457-transrepform1-v1.docx (246 kB)
Transparent reporting form

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