Journal
Elife
Publication Date
2021
Volume
10
First Page
e67292
Document Type
Open Access Publication
DOI
10.7554/eLife.67292
Rights and Permissions
eLife 2021;10:e67292 DOI: 10.7554/eLife.67292. © 2021, Gustafsson et al. This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited.
Recommended Citation
Gustafsson, Jenny K.; Davis, Jazmyne E.; Rappai, Tracy; McDonald, Keely G.; Kulkarni, Devesha H.; Knoop, Kathryn A.; Hogan, Simon P.; Fitzpatrick, James A.J.; Lencer, Wayne I.; and Newberry, Rodney D., "Intestinal goblet cells sample and deliver lumenal antigens by regulated endocytic uptake and transcytosis." Elife. 10, e67292 (2021).
https://digitalcommons.wustl.edu/open_access_pubs/10967
elife-67292-video1.mp4 (7351 kB)
Animation of the 3D model of the focused ion beam scanning electron microscopy (FIB-SEM) data. Green: Mucin granules, light blue: nucleus, red: dextran in vesicular and endosomal structures, dark blue: dextran in lysosomes and multi-vesicular bodies (MVBs) and purple: dextran in the trans-Golgi network (TGN).
elife-67292-video2.mp4 (4527 kB)
Animation of the focused ion beam scanning electron microscopy (FIB-SEM) pictures and the corresponding segmentation that the model is based on. Upper left panel: FIB-SEM pictures, upper right panel: segmentation of the nucleus (blue), mucin granuels (green), dextran in endosomes/vesicles (red), dextran in MVBs and lysosomes (orange). Lower left panel: segmentation of dextran in the trans-Golgi network (TGN) (blue).
elife-67292-transrepform1-v2.docx (246 kB)
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