Small molecule SARM1 inhibitors recapitulate the SARM1 -/- phenotype and allow recovery of a metastable pool of axons fated to degenerate

Authors

Robert O Hughes, Disarm Therapeutics
Todd Bosanac, Disarm Therapeutics
Xianrong Mao, Washington University School of Medicine in St. Louis
Thomas M Engber, Disarm Therapeutics
Aaron DiAntonio, Washington University School of Medicine in St. Louis
Jeffrey Milbrandt, Washington University School of Medicine in St. Louis
Rajesh Devraj, Disarm Therapeutics
Raul Krauss, Disarm Therapeutics

Journal

Cell Reports

Publication Date

1-5-2021

Volume

34

Issue

1

First Page

108588

Document Type

Open Access Publication

DOI

10.1016/j.celrep.2020.108588

Rights and Permissions

Hughes RO, Bosanac T, Mao X, Engber TM, DiAntonio A, Milbrandt J, Devraj R, Krauss R. Small Molecule SARM1 Inhibitors Recapitulate the SARM1-/- Phenotype and Allow Recovery of a Metastable Pool of Axons Fated to Degenerate. Cell Rep. 2021 Jan 5;34(1):108588. doi: 10.1016/j.celrep.2020.108588. Copyright 2020 The Author(s). This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

Recommended Citation

Hughes, Robert O; Bosanac, Todd; Mao, Xianrong; Engber, Thomas M; DiAntonio, Aaron; Milbrandt, Jeffrey; Devraj, Rajesh; and Krauss, Raul, "Small molecule SARM1 inhibitors recapitulate the SARM1 -/- phenotype and allow recovery of a metastable pool of axons fated to degenerate." Cell Reports. 34, 1. 108588 (2021).
https://digitalcommons.wustl.edu/open_access_pubs/11202