6-Thioguanine blocks SARS-CoV-2 replication by inhibition of PLpro

Authors

Caleb D Swaim, University of Texas at Austin
Varun Dwivedi, Texas Biomedical Research Institute
Yi-Chieh Perng, Washington University School of Medicine in St. Louis
Xu Zhao, University of Texas at Austin
Larissa A Canadeo, University of Texas at Austin
Houda H Harastani, Washington University School of Medicine in St. Louis
Tamarand L Darling, Washington University School of Medicine in St. Louis
Adrianus C M Boon, Washington University School of Medicine in St. Louis
Deborah J Lenschow, Washington University School of Medicine in St. Louis
Viraj Kulkarni, Texas Biomedical Research Institute
Jon M Huibregtse, University of Texas at Austin

Journal

iScience

Publication Date

10-22-2021

Volume

24

Issue

10

First Page

103213

Document Type

Open Access Publication

DOI

10.1016/j.isci.2021.103213

Rights and Permissions

Swaim CD, Dwivedi V, Perng YC, Zhao X, Canadeo LA, Harastani HH, Darling TL, Boon ACM, Lenschow DJ, Kulkarni V, Huibregtse JM. 6-Thioguanine blocks SARS-CoV-2 replication by inhibition of PLpro. iScience. 2021 Oct 22;24(10):103213. doi: 10.1016/j.isci.2021.103213. Copyright 2021 The Author(s). This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

Recommended Citation

Swaim, Caleb D; Dwivedi, Varun; Perng, Yi-Chieh; Zhao, Xu; Canadeo, Larissa A; Harastani, Houda H; Darling, Tamarand L; Boon, Adrianus C M; Lenschow, Deborah J; Kulkarni, Viraj; and Huibregtse, Jon M, "6-Thioguanine blocks SARS-CoV-2 replication by inhibition of PLpro." iScience. 24, 10. 103213 (2021).
https://digitalcommons.wustl.edu/open_access_pubs/11428