Inhibiting Mycobacterium abscessus cell wall synthesis: Using a novel diazabicyclooctane β-lactamase inhibitor to augment β-lactam action

Authors

Khalid M Dousa, Case Western Reserve University
David C Nguyen, University Hospitals Cleveland Medical Center
Sebastian G Kurz, Mount Sinai National Jewish Health Respiratory Institute
Magdalena A Taracila, Case Western Reserve University School of Medicine
Christopher R Bethel, Louis Stokes Veterans Affairs Medical Center
William Schinabeck, Bates College
Barry N Kreiswirth, Hackensack Meridian Health
Sheldon T Brown, Icahn School of Medicine at Mount Sinai
W Henry Boom, University Hospitals Cleveland Medical Center
Richard S Hotchkiss, Washington University School of Medicine in St. Louis
Kenneth E Remy, UH Rainbow Babies & Children’s Hospital
Frank J Jacono, Case Western Reserve University
Charles L Daley, National Jewish Health
Steven M Holland, National Institute of Allergy and Infectious Diseases
Alita A Miller, Entasis Therapeutics
Robert A Bonomo, Case Western Reserve University School of Medicine

Journal

mBio

Publication Date

1-25-2022

Volume

13

Issue

1

First Page

e0352921

Document Type

Open Access Publication

DOI

10.1128/MBIO.03529-21

Rights and Permissions

Dousa KM, Nguyen DC, Kurz SG, Taracila MA, Bethel CR, Schinabeck W, Kreiswirth BN, Brown ST, Boom WH, Hotchkiss RS, Remy KE, Jacono FJ, Daley CL, Holland SM, Miller AA, Bonomo RA. Inhibiting Mycobacterium abscessus Cell Wall Synthesis: Using a Novel Diazabicyclooctane β-Lactamase Inhibitor To Augment β-Lactam Action. mBio. 2022 Jan 25;13(1):e0352921. doi.org/10.1128/MBIO.03529-21 This is a work of the U.S. Government and is not subject to copyright protection in the United States. Foreign copyrights may apply.

Recommended Citation

Dousa, Khalid M; Nguyen, David C; Kurz, Sebastian G; Taracila, Magdalena A; Bethel, Christopher R; Schinabeck, William; Kreiswirth, Barry N; Brown, Sheldon T; Boom, W Henry; Hotchkiss, Richard S; Remy, Kenneth E; Jacono, Frank J; Daley, Charles L; Holland, Steven M; Miller, Alita A; and Bonomo, Robert A, "Inhibiting Mycobacterium abscessus cell wall synthesis: Using a novel diazabicyclooctane β-lactamase inhibitor to augment β-lactam action." mBio. 13, 1. e0352921 (2022).
https://digitalcommons.wustl.edu/open_access_pubs/11884