A pharmacokinetic analysis of tobramycin in patients less than five years of age with cystic fibrosis: Assessment of target attainment with extended-interval dosing through simulation

Authors

Kevin J Downes, Children's Hospital of Philadelphia
Austyn Grim, Texas Children's Hospital
Laura Shanley, Children's Hospital of Philadelphia
Ronald C Rubenstein, Washington University School of Medicine in St. Louis
Athena F Zuppa, Children's Hospital of Philadelphia
Marc R Gastonguay, Metrum Research Group

Journal

Antimicrobial agents and chemotherapy

Publication Date

5-17-2022

Volume

66

Issue

5

First Page

e0237721

Document Type

Open Access Publication

DOI

10.1128/aac.02377-21

Rights and Permissions

Downes KJ, Grim A, Shanley L, Rubenstein RC, Zuppa AF, Gastonguay MR. A Pharmacokinetic Analysis of Tobramycin in Patients Less than Five Years of Age with Cystic Fibrosis: Assessment of Target Attainment with Extended-Interval Dosing through Simulation. Antimicrob Agents Chemother. 2022 May 17;66(5):e0237721. doi.org/10.1128/aac.02377-21

Recommended Citation

Downes, Kevin J; Grim, Austyn; Shanley, Laura; Rubenstein, Ronald C; Zuppa, Athena F; and Gastonguay, Marc R, "A pharmacokinetic analysis of tobramycin in patients less than five years of age with cystic fibrosis: Assessment of target attainment with extended-interval dosing through simulation." Antimicrobial agents and chemotherapy. 66, 5. e0237721 (2022).
https://digitalcommons.wustl.edu/open_access_pubs/11926