A long-acting interleukin-7, rhIL-7-hyFc, enhances CAR T cell expansion, persistence, and anti-tumor activity

Authors

Miriam Y Kim, Washington University School of Medicine in St. Louis
Reyka Jayasinghe, Washington University School of Medicine in St. Louis
Jessica M Devenport, Washington University School of Medicine in St. Louis
Julie K Ritchey, Washington University School of Medicine in St. Louis
Michael P Rettig, Washington University School of Medicine in St. Louis
Julie O'Neal, Washington University School of Medicine in St. Louis
Karl W Staser, Washington University School of Medicine in St. Louis
Krista M Kennerly, Washington University School of Medicine in St. Louis
Alun J Carter, Washington University School of Medicine in St. Louis
Feng Gao, Washington University School of Medicine in St. Louis
Byung Ha Lee, NeoImmuneTech, Inc.
Matthew L Cooper, Washington University School of Medicine in St. Louis
John F DiPersio, Washington University School of Medicine in St. Louis

Journal

Nature Communications

Publication Date

6-13-2022

Volume

13

Issue

1

First Page

3296

Document Type

Open Access Publication

DOI

10.1038/s41467-022-30860-0

Rights and Permissions

Kim, M.Y., Jayasinghe, R., Devenport, J.M. et al. A long-acting interleukin-7, rhIL-7-hyFc, enhances CAR T cell expansion, persistence, and anti-tumor activity. Nat Commun 13, 3296 (2022). https://doi.org/10.1038/s41467-022-30860-0 This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

Recommended Citation

Kim, Miriam Y; Jayasinghe, Reyka; Devenport, Jessica M; Ritchey, Julie K; Rettig, Michael P; O'Neal, Julie; Staser, Karl W; Kennerly, Krista M; Carter, Alun J; Gao, Feng; Lee, Byung Ha; Cooper, Matthew L; and DiPersio, John F, "A long-acting interleukin-7, rhIL-7-hyFc, enhances CAR T cell expansion, persistence, and anti-tumor activity." Nature Communications. 13, 1. 3296 (2022).
https://digitalcommons.wustl.edu/open_access_pubs/12055