Optimizing read mapping to reference genomes to determine composition and species prevalence in microbial communities

John Martin, Washington University School of Medicine in St. Louis
Sean Sykes, The Broad Institute of MIT and Harvard, Cambridge
Sarah Young, The Broad Institute of MIT and Harvard, Cambridge
Karthik Kota, Washington University School of Medicine in St. Louis
Ravi Sanka, J. Craig Venter Institute, Rockville
Nihar Sheth, Virginia Commonwealth University
Joshua Orvis, University of Maryland - Baltimore
Erica Sodergren, Washington University School of Medicine in St. Louis
Zhengyuan Wang, Washington University School of Medicine in St. Louis
George M. Weinstock, Washington University School of Medicine in St. Louis
Makedonka Mitreva, Washington University School of Medicine in St. Louis

Abstract