P-glycoprotein deficiency at the blood-brain barrier increases amyloid-β deposition in an Alzheimer disease mouse model

Authors

John R. Cirrito, Washington University School of Medicine in St. Louis
Rashid Deane, University of RochesterFollow
Anne M. Fagan, Washington University School of Medicine in St. LouisFollow
Michael L. Spinner, Washington University School of Medicine in St. Louis
Maia Parsadanian, Washington University School of Medicine in St. Louis
Mary Beth Finn, Washington University School of Medicine in St. LouisFollow
Hong Jiang, Washington University School of Medicine in St. LouisFollow
Julie L. Prior, Washington University School of Medicine in St. Louis
Abhay Sagare, University of Rochester
Kelly R. Bales, Lilly Research LaboratoriesFollow
Steven M. Paul, Lilly Research Laboratories
Berislav V. Zlokovic, University of Rochester
David Piwinca-Worms, Washington University School of Medicine in St. Louis
David M. Holtzman, Washington University School of Medicine in St. LouisFollow

Journal

The Journal of Clinical Investigation

Publication Date

2005

Volume

115

Issue

11

Inclusive Pages

3285-3290

Document Type

Open Access Publication

DOI

10.1172/JCI25247

Rights and Permissions

Published in Volume 115, Issue 11 (November 1, 2005) J Clin Invest. 2005;115(11):3285–3290. doi:10.1172/JCI25247. Copyright © 2005, American Society for Clinical

Recommended Citation

Cirrito, John R.; Deane, Rashid; Fagan, Anne M.; Spinner, Michael L.; Parsadanian, Maia; Finn, Mary Beth; Jiang, Hong; Prior, Julie L.; Sagare, Abhay; Bales, Kelly R.; Paul, Steven M.; Zlokovic, Berislav V.; Piwinca-Worms, David; and Holtzman, David M., "P-glycoprotein deficiency at the blood-brain barrier increases amyloid-β deposition in an Alzheimer disease mouse model." The Journal of Clinical Investigation. 115, 11. 3285-3290. (2005).
https://digitalcommons.wustl.edu/open_access_pubs/1522