Targeting Chk1 in p53-deficient triple-negative breast cancer is therapeutically beneficial in human-in-mouse tumor models

Authors

Cynthia X. Ma, Washington University School of Medicine in St. LouisFollow
Shirong Cai, Washington University School of Medicine in St. Louis
Shunqiang Li, Washington University School of Medicine in St. Louis
Christine E. Ryan, Washington University School of Medicine in St. Louis
Zhangfang Guo, Washington University School of Medicine in St. Louis
W. Timothy Schaiff, Washington University School of Medicine in St. Louis
Li Lin, Washington University School of Medicine in St. Louis
Jeremy Hoog, Washington University School of Medicine in St. Louis
Reece J. Goiffon, Washington University School of Medicine in St. Louis
Aleix Prat, University of North Carolina at Chapel Hill
Rebecca L. Aft, Washington University School of Medicine in St. Louis
Matthew J. Ellis, Washington University School of Medicine in St. LouisFollow
Helen Piwnica-Worms, Washington University School of Medicine in St. Louis

Journal

The Journal of Clinical Investigation

Publication Date

2012

Volume

122

Issue

4

Inclusive Pages

1541-1552

Document Type

Open Access Publication

DOI

10.1172/JCI58765

Rights and Permissions

Targeting Chk1 in p53-deficient triple-negative breast cancer is therapeutically beneficial in human-in-mouse tumor models Cynthia X. Ma, Shirong Cai, Shunqiang Li, Christine E. Ryan, Zhanfang Guo, W. Timothy Schaiff, Li Lin, Jeremy Hoog, Reece J. Goiffon, Aleix Prat, Rebecca L. Aft, Matthew J. Ellis, Helen Piwnica-Worms Published in Volume 122, Issue 4 J Clin Invest. 2012; 122(4):1541–1552 doi:10.1172/JCI58765

Recommended Citation

Ma, Cynthia X.; Cai, Shirong; Li, Shunqiang; Ryan, Christine E.; Guo, Zhangfang; Schaiff, W. Timothy; Lin, Li; Hoog, Jeremy; Goiffon, Reece J.; Prat, Aleix; Aft, Rebecca L.; Ellis, Matthew J.; and Piwnica-Worms, Helen, "Targeting Chk1 in p53-deficient triple-negative breast cancer is therapeutically beneficial in human-in-mouse tumor models." The Journal of Clinical Investigation. 122, 4. 1541-1552. (2012).
https://digitalcommons.wustl.edu/open_access_pubs/1687