Mechanistic characterization of the 5′-triphosphate-dependent activation of PKR: Lack of 5′-end nucleobase specificity, evidence for a distinct triphosphate binding site, and a critical role for the dsRBD

Authors

Rebecca Toroney, Pennsylvania State University
Chelsea M. Hull, Pennsylvania State University
Joshua E. Sokoloski, Washington University School of Medicine in St. Louis
Philip C. Bevilacqua, Pennsylvania State University

Journal

RNA

Publication Date

2012

Volume

18

Issue

10

Inclusive Pages

1862-1874

Document Type

Open Access Publication

DOI

10.1261/rna.034520.112

Rights and Permissions

Mechanistic characterization of the 5′-triphosphate-dependent activation of PKR: Lack of 5′-end nucleobase specificity, evidence for a distinct triphosphate binding site, and a critical role for the dsRBD Rebecca Toroney, Chelsea M. Hull, Joshua E. Sokoloski, and Philip C. Bevilacqua RNA October 2012 18: 1862-1874; Published in Advance August 21, 2012, doi:10.1261/rna.034520.112

Recommended Citation

Toroney, Rebecca; Hull, Chelsea M.; Sokoloski, Joshua E.; and Bevilacqua, Philip C., "Mechanistic characterization of the 5′-triphosphate-dependent activation of PKR: Lack of 5′-end nucleobase specificity, evidence for a distinct triphosphate binding site, and a critical role for the dsRBD." RNA. 18, 10. 1862-1874. (2012).
https://digitalcommons.wustl.edu/open_access_pubs/4167