Journal
Nature Communications
Publication Date
2015
Volume
3
Inclusive Pages
719
Document Type
Open Access Publication
DOI
10.1038/ncomms1711
Rights and Permissions
S.I. Fraley, et al. 05 March 2012. Dimensional and temporal controls of three-dimensional cell migration by zyxin and binding partners. Nature communications. Art. No. 719. DOI: 10.1038/ncomms1711. http://www.nature.com/ncomms/journal/v3/n3/full/ncomms1711.html
Recommended Citation
Fraley, Stephanie I.; Feng, Yunfeng; Giri, Anjil; Longmore, Gregory D.; and Wirtz, Denis, "Dimensional and temporal controls of three-dimensional cell migration by zyxin and binding partners." Nature Communications. 3, 719. (2015).
https://digitalcommons.wustl.edu/open_access_pubs/4340
ncomms1711-s1.pdf (3521 kB)
Supplementary Figures S1–S4
ncomms1711-s2.wmv (3216 kB)
Zyxin-depleted cell moving in a 3D matrix. An example of a HT1080 cells (human fibrosarcoma) depleted of zyxin undergoing highly regular periodic oscillatory migration inside a 3D collagen I matrix.
ncomms1711-s3.wmv (4583 kB)
Zyxin-depleted cell moving in a 3D matrix- second example. Another example of a HT1080 cells (human fibrosarcoma) depleted of zyxin undergoing highly regular periodic oscillatory migration inside a 3D collagen I matrix.
ncomms1711-s4.wmv (5159 kB)
Wild-type cell moving on a 2D substrate. A wild-type HT1080 cell undergoes conventional random migration on a 2D collagen-coated substrate.
ncomms1711-s5.wmv (5641 kB)
Zyxin-depleted cell moving on a 2D substrate. A HT1080 cell depleted of zyxin undergoes conventional random migration on a 2D collagen-coated substrate.
ncomms1711-s6.wmv (2136 kB)
Wild-type cell moving in a 3D matrix. An example of a wild-type HT1080 cells undergoing conventional random migration inside a 3D collagen I matrix.
ncomms1711-s7.wmv (1910 kB)
Wild-type cell moving in a 3D matrix - second example. Another example of a wild-type HT1080 cells undergoing conventional random migration inside a 3D collagen I matrix.
ncomms1711-s8.wmv (3004 kB)
Wild-type cell moving along a 1D stripe. A wild-type HT1080 cell undergoes 1D temporarily random migration along a 1D collagen-coated stripe flanked with PEG stripes.
ncomms1711-s9.wmv (3060 kB)
Supplementary Figures S1–S4
ncomms1711-s2.wmv (3216 kB)
Zyxin-depleted cell moving in a 3D matrix. An example of a HT1080 cells (human fibrosarcoma) depleted of zyxin undergoing highly regular periodic oscillatory migration inside a 3D collagen I matrix.
ncomms1711-s3.wmv (4583 kB)
Zyxin-depleted cell moving in a 3D matrix- second example. Another example of a HT1080 cells (human fibrosarcoma) depleted of zyxin undergoing highly regular periodic oscillatory migration inside a 3D collagen I matrix.
ncomms1711-s4.wmv (5159 kB)
Wild-type cell moving on a 2D substrate. A wild-type HT1080 cell undergoes conventional random migration on a 2D collagen-coated substrate.
ncomms1711-s5.wmv (5641 kB)
Zyxin-depleted cell moving on a 2D substrate. A HT1080 cell depleted of zyxin undergoes conventional random migration on a 2D collagen-coated substrate.
ncomms1711-s6.wmv (2136 kB)
Wild-type cell moving in a 3D matrix. An example of a wild-type HT1080 cells undergoing conventional random migration inside a 3D collagen I matrix.
ncomms1711-s7.wmv (1910 kB)
Wild-type cell moving in a 3D matrix - second example. Another example of a wild-type HT1080 cells undergoing conventional random migration inside a 3D collagen I matrix.
ncomms1711-s8.wmv (3004 kB)
Wild-type cell moving along a 1D stripe. A wild-type HT1080 cell undergoes 1D temporarily random migration along a 1D collagen-coated stripe flanked with PEG stripes.
ncomms1711-s9.wmv (3060 kB)
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