Journal
Breast Cancer Research
Publication Date
2016
Volume
18
Issue
1
Inclusive Pages
13
Document Type
Open Access Publication
DOI
10.1186/s13058-016-0673-9
Rights and Permissions
Powell et al. Breast Cancer Research (2016) 18:13 DOI 10.1186/s13058-016-0673-9
Recommended Citation
Powell, Emily; Shao, Jiansu; Yuan, Yuan; Chen, Hsiang-Chun; Cai, Shirong; Echeverria, Gloria V.; Mistry, Nipun; Decker, Keith F.; Schlosberg, Christopher; Do, Kim-Anh; Edwards, John R.; Liang, Han; Piwnica-Worms, David; and Piwnica-Worms, Helen, "p53 deficiency linked to B cell translocation gene 2 (BTG2) loss enhances metastatic potential by promoting tumor growth in primary and metastatic sites in patient-derived xenograft (PDX) models of triple-negative breast cancer." Breast Cancer Research. 18, 1. 13. (2016).
https://digitalcommons.wustl.edu/open_access_pubs/4532
Mini-signature of genes that interact with the p53 pathway and associated p values
s13058-016-0673-9-s2.pdf (977 kB)
Silencing of p53 increased cell proliferation in vitro
s13058-016-0673-9-s3.pdf (134 kB)
p53 silencing does not increase number of tumor-initiating cells
s13058-016-0673-9-s4.pdf (73 kB)
p53 silencing increases growth at metastatic sites
s13058-016-0673-9-s5.pdf (2462 kB)
CTC number correlates with mammary tumor size
s13058-016-0673-9-s6.pdf (123 kB)
RNA-Seq signature of genes that are deregulated upon p53 loss in BC3 mammary tumors
s13058-016-0673-9-s7.pdf (63 kB)
Pathway analysis of RNA-Seq expression signature consisting of genes deregulated upon p53 knockdown
s13058-016-0673-9-s8.pdf (1964 kB)
Ectopic expression of BTG2 in BC3-p53KD cells reduces cell proliferation in vitro