Journal
Nature Communications
Publication Date
2016
Volume
7
Inclusive Pages
12498
Document Type
Open Access Publication
DOI
10.1038/ncomms12498
Rights and Permissions
C.A. Miller, et al. 09 August 2016. Aromatase inhibition remodels the clonal architecture of estrogen-receptor-positive breast cancers. Nature communications. Art. No. 12498. DOI: 10.1038/ncomms12498. http://www.nature.com/ncomms/2016/160809/ncomms12498/full/ncomms12498.html
Recommended Citation
Miller, Christopher A.; Gindin, Yevgeniy; Lu, Charles; Griffith, Obi L.; Griffith, Malachi; Shen, Dong; Hoog, Jeremy; Li, Tiandao; Larson, David E.; Watson, Mark; Davies, Sherri R.; Snider, Jacqueline; Walsh, Thomas; Colditz, Graham A.; DeSchryver, Katherine; Wilson, Richard K.; Mardis, Elaine R.; Ellis, Matthew J.; and et al, "Aromatase inhibition remodels the clonal architecture of estrogen-receptor-positive breast cancers." Nature Communications. 7, 12498. (2016).
https://digitalcommons.wustl.edu/open_access_pubs/5210
Supplementary Figures 1-8, Supplementary Notes 1-5, Supplementary Data 1-12, and Supplementary Software 1-2
ncomms12498-s16.pdf (258 kB)
Peer review file
ncomms12498-s2.xlsx (15 kB)
Clinical characteristics of cohort
ncomms12498-s3.xls (1260 kB)
Protein-coding (tier1) SNVs and Indels
ncomms12498-s4.xls (18271 kB)
Non-protein-coding (tier2-3) SNVs and Indels
ncomms12498-s5.xls (60 kB)
Sequencing Coverage and Purity
ncomms12498-s6.xls (288 kB)
Validated structural variants
ncomms12498-s7.xls (80 kB)
Gene fusions detected using INTEGRATE
ncomms12498-s8.xlsx (19543 kB)
Gene expression values (expressed in FPKM).
ncomms12498-s9.xlsx (12 kB)
Mutations detected in pre-malignant (DCIS) samples from BRC15
ncomms12498-s10.xls (32 kB)
Subclonal VAFs
ncomms12498-s11.xlsx (11 kB)
List of the 83 genes targeted by the breast cancer-related gene panel
ncomms12498-s12.xls (39 kB)
Mutations detected in targeted sequencing of extension cohort
ncomms12498-s13.xls (123 kB)
Differentially expressed genes between responders and non- responders
ncomms12498-s14.zip (6820 kB)
All data and scripts used for clonal clustering
ncomms12498-s15.zip (43 kB)
