Neurodegenerative disease mutations in TREM2 reveal a functional surface and distinct loss-of-function mechanisms

Authors

Daniel L. Kober, Washington University School of Medicine
Jennifer M. Alexander-Brett, Washington University School of Medicine
Celeste M. Karch, Washington University School of Medicine
Carlos Cruchaga, Washington University School of Medicine
Marco Colonna, Washington University School of Medicine
Michael J. Holtzman, Washington University School of Medicine
Thomas J. Brett, Washington University School of Medicine

Journal

Elife

Publication Date

2016

Volume

5

Issue

e20391

Inclusive Pages

1-24

Document Type

Open Access Publication

DOI

10.7554/eLife.20391.001

Rights and Permissions

Kober, D. L., Alexander-Brett, J. M., Karch, C. M., Cruchaga, C., Colonna, M., Holtzman, M. J., and Brett, T. J. 2016. Neurodegenerative disease mutations in TREM2 reveal a functional surface and distinct loss-of-function mechanisms. eLife 2016;5:e20391. DOI: http://dx.doi.org/10.7554/eLife.20391.001.

Recommended Citation

Kober, Daniel L.; Alexander-Brett, Jennifer M.; Karch, Celeste M.; Cruchaga, Carlos; Colonna, Marco; Holtzman, Michael J.; and Brett, Thomas J., "Neurodegenerative disease mutations in TREM2 reveal a functional surface and distinct loss-of-function mechanisms." Elife. 5, e20391. 1-24. (2016).
https://digitalcommons.wustl.edu/open_access_pubs/5455