Journal
Nature Communications
Publication Date
2017
Volume
8
Document Type
Open Access Publication
DOI
10.1038/ncomms14977
Rights and Permissions
Justice, A. E. et al. Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. Nat. Commun. 8, 14977 doi: 10.1038/ncomms14977 (2017). This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ Copyright The Author(s) 2017
Recommended Citation
Sung, Yun Ju; Rao, D.C.; Rice, Treva; Heath, Andrew C.; Madden, Pamela A.F.; Feitosa, Mary F.; Barata, Llilda; Czajkowski, Jacek; Borecki, Ingrid B.; and et al, "Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits." Nature Communications. 8, (2017).
https://digitalcommons.wustl.edu/open_access_pubs/5802
Supplementary Figures, Supplementary Tables, Supplementary Notes and Supplementary References
Peer Review File.pdf (806 kB)
Supplementary Data 1.xlsx (68 kB)
BMI association results for all ancestries meta-analyses. Significant SNPs for BMI across all approaches (1-SNPadjSMK, 2-SNPjoint, 3-SNPint, 4-SNPscreen) and strata (C=Combined Men and Women, W=Women-only, M=Men-only) for combined ancestries meta-analyses. Summary statistics are presented from stage1 plus stage 2 results.
Supplementary Data 2.xlsx (73 kB)
WCadjBMI association results for all ancestries meta-analyses. Significant SNPs for WCadjBMI across all approaches (1-SNPadjSMK, 2-SNPjoint, 3-SNPint, 4-SNPscreen) and strata (C=Combined Men and Women, W=Women-only, M=Men-only) for combined ancestries meta-analyses. Summary statistics are presented from stage1 plus stage 2 results.
Supplementary Data 3.xlsx (49 kB)
WHRadjBMI association results for all ancestries meta-analyses. Significant SNPs for WHRadjBMI across all approaches (1-SNPadjSMK, 2-SNPjoint, 3-SNPint, 4-SNPscreen) and strata (C=Combined Men and Women, W=Women-only, M=Men-only) for combined ancestries meta-analyses. Summary statistics are presented from stage1 plus stage 2 results.
Supplementary Data 4.xlsx (58 kB)
BMI association results for European meta-analyses. Significant SNPs for BMI across all approaches (1-SNPadjSMK, 2-SNPjoint, 3-SNPint, 4-SNPscreen) and strata (C=Combined Men and Women, W=Women-only, M=Men-only) for European-only analyses. Summary statistics are presented from stage1 plus stage 2 results.
Supplementary Data 5.xlsx (67 kB)
WCadjBMI association results for European meta-analyses. Significant SNPs for WCadjBMI across all approaches (1-SNPadjSMK, 2-SNPjoint, 3-SNPint, 4-SNPscreen) and strata (C=Combined Men and Women, W=Women-only, M=Men-only) for European-only analyses. Summary statistics are presented from stage1 plus stage 2 results.
Supplementary Data 6.xlsx (53 kB)
WHRadjBMI association results for European meta-analyses. Significant SNPs for WHRadjBMI across all approaches (1-SNPadjSMK, 2-SNPjoint, 3-SNPint, 4-SNPscreen) and strata (C=Combined Men and Women, W=Women-only, M=Men-only) for European-only analyses. Summary statistics are presented from stage1 plus stage 2 results.
Supplementary Data 7.xlsx (124 kB)
Lookup of known main effects SNPS. Lookups of previously identified main effects loci in the current combined ancestries meta-analyses results for BMI, WCadjBMI, and WHRadjBMI.
Supplementary Data 8.xlsx (20 kB)
Look up of novel loci from the current analyses in previous GWAS of BMI, WC, WCadjBMI, WHR, WHRadjBMI, height and three smoking behavior traits (Ever/Never smoker, Current/Not Current Smoker, and Smoking Qantity).
