Journal
Alzheimer's and Dementia: Translational Research and Clinical Interventions
Publication Date
2017
Volume
3
Issue
4
Inclusive Pages
507-512
Document Type
Open Access Publication
DOI
10.1016/j.trci.2017.08.002
Rights and Permissions
Sha SJ, Miller ZA, Min S, et al (2017) An 8-week, open-label, dose-finding study of nimodipine for the treatment of progranulin insufficiency from GRN gene mutations. Alzheimer's & Dementia: Translational Research & Clinical Interventions, 3(4):507-512. https://doi.org/10.1016/j.trci.2017.08.002 Copyright 2017 The Authors. Published by Elsevier Inc. on behalf of the Alzheimer’s Association. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
Recommended Citation
Fagan, Anne M. and et al, "An 8-week, open-label, dose-finding study of nimodipine for the treatment of progranulin insufficiency from GRN gene mutations." Alzheimer's and Dementia: Translational Research and Clinical Interventions. 3, 4. 507-512. (2017).
https://digitalcommons.wustl.edu/open_access_pubs/6255
Treatment with ionomycin or thapsigargin lowered levels of secreted PGRN in microglial BV2 cells.
Figure2.jpg (159 kB)
CONSORT diagram of subject enrollment.
Figure3.jpg (122 kB)
Nimodipine dosing.
1-s2.0-S2352873717300483-mmc1.docx (45 kB)