The autism-linked UBE3A T485A mutant E3 ubiquitin ligase activates the Wnt/β-catenin pathway by inhibiting the proteasome

Authors

Jason J. Yi, Washington University School of Medicine in St. Louis
Smita R. Paranjape, Washington University School of Medicine in St. Louis
Matthew P. Walker, Washington University School of Medicine in St. Louis
Rajarshi Choudhury, University of North Carolina at Chapel Hill
Justin M. Wolter, Washington University School of Medicine in St. Louis
Giulia Fragola, Washington University School of Medicine in St. Louis
Michael J. Emanuele, University of North Carolina at Chapel Hill
Michael B. Major, Washington University School of Medicine in St. Louis
Mark J. Zylka, Washington University School of Medicine in St. Louis

Journal

Journal of Biological Chemistry

Publication Date

2017

Volume

292

Issue

30

Inclusive Pages

12503-12515

Document Type

Open Access Publication

DOI

10.1074/jbc.M117.788448

Rights and Permissions

This research was originally published in the Journal of Biological Chemistry. Yi JJ, Paranjape SR, Walker MP, Choudhury R, Wolter JM, Fragola G, Emanuele MJ, Major MB, Zylka MJ. The autism-linked UBE3A T485A mutant E3 ubiquitin ligase activates the Wnt/β-catenin pathway by inhibiting the proteasome. J Biol Chem. 2017 Jul 28;292(30):12503-12515. doi: 10.1074/jbc.M117.788448 © 2017 by The American Society for Biochemistry and Molecular Biology, Inc.

Recommended Citation

Yi, Jason J.; Paranjape, Smita R.; Walker, Matthew P.; Choudhury, Rajarshi; Wolter, Justin M.; Fragola, Giulia; Emanuele, Michael J.; Major, Michael B.; and Zylka, Mark J., "The autism-linked UBE3A T485A mutant E3 ubiquitin ligase activates the Wnt/β-catenin pathway by inhibiting the proteasome." Journal of Biological Chemistry. 292, 30. 12503-12515. (2017).
https://digitalcommons.wustl.edu/open_access_pubs/6256