Cholesterol activates the G-protein coupled receptor Smoothened to promote Hedgehog signaling

Authors

Giovanni Luchetti, Stanford University School of Medicine
Ria Sircar, Stanford University School of Medicine
Jennifer H. Kong, Stanford University School of Medicine
Sigrid Nachtergaele, Stanford University School of Medicine
Andreas Sagner, The Francis Crick Institute
Eamon FX Byrne, University of Oxford
Douglas F. Covey, Washington University School of Medicine in St. Louis
Christian Siebold, University of Oxford
Rajat Rohatgi, Stanford University School of Medicine

Journal

Elife

Publication Date

2016

Volume

5

Inclusive Pages

e20304

Document Type

Open Access Publication

DOI

10.7554/eLife.20304

Rights and Permissions

Luchetti, G., Sircar, R., Kong, J. H., Nachtergaele, S., Sagner, A., Byrne, E. F. X., . . . Rohatgi, R. (2016). Cholesterol activates the G-protein coupled receptor smoothened to promote hedgehog signaling. ELife, 5(OCTOBER2016) doi:10.7554/eLife.20304.

Recommended Citation

Luchetti, Giovanni; Sircar, Ria; Kong, Jennifer H.; Nachtergaele, Sigrid; Sagner, Andreas; Byrne, Eamon FX; Covey, Douglas F.; Siebold, Christian; and Rohatgi, Rajat, "Cholesterol activates the G-protein coupled receptor Smoothened to promote Hedgehog signaling." Elife. 5, e20304. (2016).
https://digitalcommons.wustl.edu/open_access_pubs/6326