Journal
Frontiers in Immunology
Publication Date
2017
Volume
8
Inclusive Pages
1793
Document Type
Open Access Publication
DOI
10.3389/fimmu.2017.01793
Rights and Permissions
Moon Y-M, Lee S-Y, Kwok S-K, Lee SH, Kim D, Kim WK, Her Y-M, Son H-J, Kim E-K, Ryu J-G, Seo H-B, Kwon J-E, Hwang S-Y, Youn J, Seong RH, Jue D-M, Park S-H, Kim H-Y, Ahn S-M and Cho M-L (2017) The Fos-Related Antigen 1–JUNB/Activator Protein 1 Transcription Complex, a Downstream Target of Signal Transducer and Activator of Transcription 3, Induces T Helper 17 Differentiation and Promotes Experimental Autoimmune Arthritis. Front. Immunol. 8:1793. doi: 10.3389/fimmu.2017.01793 © 2017 Moon, Lee, Kwok, Lee, Kim, Kim, Her, Son, Kim, Ryu, Seo, Kwon, Hwang, Youn, Seong, Jue, Park, Kim, Ahn and Cho. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
Recommended Citation
Kim, Woo Kyung and et al, "The Fos-related antigen 1–JUNB/activator protein 1 transcription complex, a downstream target of signal transducer and activator of transcription 3, induces T helper 17 differentiation and promotes experimental autoimmune arthritis." Frontiers in Immunology. 8, 1793. (2017).
https://digitalcommons.wustl.edu/open_access_pubs/6441
Table S1. Genes up-regulated by STAT3 in Th17 cells.
table 2.pdf (523 kB)
Table S2. Normalized expression of mRNA for the different AP-1 components, as assessed by RNA-seq.
table 3.pdf (230 kB)
Table S3. qPCR primers for ChIP-qPCR.
data sheet 1.pdf (279 kB)
AP-1 Subtype Switching to FRA1-JUNB, a Downstream Target of STAT3, Induces Th17 Cell Differentiation and Experimental Autoimmune Arthritis
image 1.tif (2478 kB)
Knockdown of FRA1/JUNB Decreases Th17 Cell Differentiation and Attenuates Rheumatoid Inflammation in Mice.
image 2.tif (57 kB)
T cell proportion of CD4+Tcells in Fra1/Junb Tg mice.
image 3.tif (3434 kB)
Overexpression of FRA1/JUNB Causes Th17 Cell Differentiation and Increases CIA Disease Severity.
